| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Redmile Group, LLC | 9.9% | $43.9M | 5.06M | Redmile Group, LLC | 30 Jun 2025 | |||
| JPMORGAN CHASE & CO | 7.4% | $34.8M | 3.7M | JPMORGAN CHASE & CO. | 31 Dec 2024 | |||
| BlackRock, Inc. | 7.3% | -33.6% | $34.6M | -$16.8M | 3.68M | -32.7% | BlackRock, Inc. | 31 Mar 2025 |
| BlackRock Portfolio Management LLC | 6.2% | $25.7M | 3.13M | BlackRock Portfolio Management LLC | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 6.02% | $28.1M | 2.99M | The Vanguard Group | 31 Dec 2024 | |||
| STATE STREET CORP | 4.4% | $20.6M | 2.19M | STATE STREET CORPORATION | 31 Dec 2024 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 41.4M | $399M | -$3.67M | $9.65 | 166 |
| 2025 Q2 | 42M | $345M | +$5.51M | $8.21 | 159 |
| 2025 Q1 | 41.7M | $298M | -$1.5M | $7.15 | 163 |
| 2024 Q4 | 42.1M | $325M | -$15.5M | $7.73 | 175 |
| 2024 Q3 | 43.7M | $458M | -$8.52M | $10.49 | 184 |
| 2024 Q2 | 43.8M | $512M | +$5.42M | $11.70 | 180 |
| 2024 Q1 | 42.5M | $896M | +$95.8M | $21.07 | 185 |
| 2023 Q4 | 38.1M | $684M | +$18.8M | $17.95 | 167 |
| 2023 Q3 | 37.1M | $610M | -$2.25M | $16.46 | 157 |
| 2023 Q2 | 37.1M | $742M | +$3.96M | $19.99 | 165 |
| 2023 Q1 | 37M | $700M | +$18.8M | $18.91 | 170 |
| 2022 Q4 | 35.7M | $810M | +$5.38M | $22.68 | 180 |
| 2022 Q3 | 35.1M | $927M | -$30.5M | $26.43 | 173 |
| 2022 Q2 | 36.2M | $893M | +$28.9M | $24.70 | 157 |
| 2022 Q1 | 34.9M | $1.16B | -$21M | $33.19 | 181 |
| 2021 Q4 | 35.5M | $1.16B | +$58.4M | $32.70 | 168 |
| 2021 Q3 | 33.4M | $1.4B | -$3.05M | $41.92 | 177 |
| 2021 Q2 | 33.5M | $1.3B | +$26.8M | $38.85 | 168 |
| 2021 Q1 | 32.9M | $1.12B | +$188M | $34.11 | 178 |
| 2020 Q4 | 27.3M | $1.24B | -$41.7M | $45.36 | 182 |
| 2020 Q3 | 28.5M | $785M | -$29.7M | $27.52 | 162 |
| 2020 Q2 | 29.4M | $1.08B | +$20M | $36.83 | 174 |
| 2020 Q1 | 28.9M | $937M | -$29.1M | $32.38 | 160 |
| 2019 Q4 | 29.6M | $1.21B | -$13.2M | $40.97 | 178 |
| 2019 Q3 | 29.2M | $1.04B | -$21.9M | $35.60 | 165 |
| 2019 Q2 | 29.4M | $1.51B | -$22.8M | $51.37 | 184 |
| 2019 Q1 | 30.1M | $1.73B | +$15.6M | $57.31 | 206 |
| 2018 Q4 | 29.9M | $1.26B | +$31.7M | $41.95 | 178 |
| 2018 Q3 | 28.5M | $2.15B | +$194M | $75.50 | 198 |
| 2018 Q2 | 26M | $1.87B | +$332M | $71.75 | 174 |
| 2018 Q1 | 22.4M | $668M | +$29.3M | $29.85 | 118 |
| 2017 Q4 | 21.6M | $718M | +$5.11M | $33.25 | 106 |
| 2017 Q3 | 21.4M | $704M | -$14.4M | $32.95 | 87 |
| 2017 Q2 | 22.7M | $448M | +$37.3M | $19.75 | 86 |
| 2017 Q1 | 20.8M | $401M | +$94.9M | $19.30 | 86 |
| 2016 Q4 | 18.3M | $339M | +$28.4M | $18.55 | 77 |
| 2016 Q3 | 16.9M | $237M | +$3.1M | $14.01 | 71 |
| 2016 Q2 | 17.9M | $144M | +$9.89M | $8.00 | 67 |
| 2016 Q1 | 16.6M | $180M | +$4.02M | $10.80 | 62 |
| 2015 Q4 | 15M | $247M | -$9.9M | $16.60 | 65 |
| 2015 Q3 | 14.3M | $310M | +$310M | $22.03 | 47 |