13F reference period
Q2 2026
CUSIP: 75383L102
13F reference period
Q2 2026
Institutions Reporting
160
Shares (Excl. Options)
Price
$41.67
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 160 institutions filings for Q2 2026.
Security key
75383L102
13F reference period
Q2 2026
13F holders
160
13D/G owners
6
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 75383L102:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Third Rock Ventures V, L.P. | 13% | -32% | $261,709,477 | -$35,615,682 | 6,280,525 | -12% | Third Rock Ventures V, L.P. | 30 Jun 2026 |
| Capital International Investors | 6.1% | $121,757,990 | 2,921,958 | Capital International Investors | 30 Jun 2026 | |||
| Cormorant Asset Management, LP | 5.6% | -10% | $110,738,900 | -$12,501,000 | 2,657,521 | -10% | Cormorant Asset Management, LP | 30 Jun 2026 |
| BlackRock, Inc. | 5% | $72,741,637 | 2,397,549 | BlackRock, Inc. | 31 Dec 2025 | |||
| Sofinnova Venture Partners XI, L.P. | 4.2% | $29,155,258 | 1,947,579 | Dr. James I. Healy ("Healy") | 11 Sep 2025 | |||
| JOHNSON & JOHNSON | 4.9% | $53,000,690 | 1,784,517 | JOHNSON & JOHNSON | 30 Sep 2025 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 15% | 7,172,894 | +0.06% | 0.01% | $298,894,493 |
| TRV GP V, LLC | 13% | 6,280,525 | -12% | 53% | $261,709,477 |
| ARCH Venture Management, LLC | 7.8% | 3,728,738 | 0% | 14% | $155,376,512 |
| Capital International Investors | 6.1% | 2,921,958 | -5.7% | 0.03% | $121,757,990 |
| GOLDMAN SACHS GROUP INC | 6.1% | 2,910,449 | -1.1% | 0.01% | $121,278,410 |
| BlackRock, Inc. | 5.6% | 2,699,786 | +7.7% | 0% | $112,500,083 |
| Cormorant Asset Management, LP | 5.5% | 2,657,521 | -10% | 5.7% | $110,738,900 |
| Sofinnova Investments, Inc. | 4% | 1,904,408 | 0% | 4.2% | $79,356,681 |
| JOHNSON & JOHNSON | 3.7% | 1,784,517 | 0% | 9.3% | $74,360,823 |
| Polar Capital Holdings Plc | 3.4% | 1,608,514 | -2.1% | 0.19% | $67,026,778 |
| BAKER BROS. ADVISORS LP | 3.2% | 1,547,090 | 0% | 0.32% | $64,467,240 |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.8% | 1,346,512 | +1.6% | 0% | $56,109,155 |
| TRV GP VI, LLC | 2% | 969,218 | 0% | 17% | $40,387,314 |
| STATE STREET CORP | 1.7% | 818,712 | +7.8% | 0% | $34,115,729 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.7% | 793,453 | +10% | 0% | $33,068,458 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.6% | 787,446 | -9.1% | 0% | $32,814,000 |
| PERCEPTIVE ADVISORS LLC | 1.6% | 773,342 | +15% | 0.5% | $32,225,161 |
| Vestal Point Capital, LP | 1.5% | 730,000 | -49% | 0.71% | $30,419,100 |
| ALLIANCEBERNSTEIN L.P. | 1.4% | 693,384 | -4.7% | 0.01% | $21,695,985 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1.3% | 644,082 | -30% | 0% | $26,838,898 |
| Siren, L.L.C. | 1.3% | 641,469 | 0% | 0.54% | $26,730,013 |
| Capital World Investors | 1.2% | 551,657 | +2.8% | 0% | $22,987,547 |
| T. Rowe Price Investment Management, Inc. | 0.82% | 393,200 | -37% | 0.01% | $16,385,000 |
| DIMENSIONAL FUND ADVISORS LP | 0.76% | 362,114 | +61% | 0% | $15,087,064 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 0.75% | 359,944 | +12% | 0% | $14,998,866 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 1,963,268 | $65,956,693 | -$1,183,931 | $33.60 | 22 |
| 2026 Q2 | 51,271,114 | $2,129,194,307 | -$48,032,179 | $41.67 | 160 |
| 2026 Q1 | 52,482,926 | $1,641,485,641 | +$41,369,429 | $31.29 | 146 |
| 2025 Q4 | 51,084,271 | $1,549,894,668 | +$54,540,100 | $30.34 | 144 |
| 2025 Q3 | 49,276,697 | $1,463,478,389 | +$335,895,056 | $29.70 | 123 |
| 2025 Q2 | 38,494,803 | $437,875,302 | +$4,896,059 | $11.37 | 81 |
| 2025 Q1 | 38,102,588 | $382,320,591 | +$11,241,443 | $10.03 | 77 |
| 2024 Q4 | 36,577,539 | $648,890,836 | -$29,671 | $17.74 | 69 |
| 2024 Q3 | 28,444,042 | $581,877,476 | +$37,552,009 | $20.48 | 55 |
| 2024 Q2 | 25,558,517 | $593,435,106 | +$593,435,106 | $23.26 | 35 |