Security key
74168J101
- Type / Class
- Equity / COMMON STOCK
- Shares outstanding
- 181,672,212
- Total 13F shares
- 97,023,671
- Share change
- +4,676,226
- Total reported value
- $336,614,188
- Put/Call ratio
- 131%
- Price per share
- $3.47
- Number of holders
- 182
- Value change
- +$756,626
- Number of buys
- 108
- Number of sells
- 65
Report period
Q4 2025
Institutions
182
Top holders
10
PRME full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
Prime Medicine, Inc. SEC filings
Prime Medicine, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 74168J101
Recent filing periods:
Top shareholders of PRME - Prime Medicine, Inc. - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| GV 2019, L.P. |
13D/G
|
Alphabet Holdings LLC |
12%
|
16,562,498
|
$91,756,239 | $0 | 30 Sep 2025 | |
| ARCH Venture Fund XII, L.P. |
13D/G
|
Robert Nelsen |
10%
|
18,587,036
|
$80,853,607 | $0 | 07 Aug 2025 | |
| Newpath Partners, L.P. |
13D/G
|
— |
4.7%
|
6,105,679
|
$9,769,086 | $0 | 31 Dec 2024 | |
| FMR LLC |
3/4/5
13D/G
13F
|
Other* · Company |
3.8%
from 13D/G
|
8,462,946
|
$126,699,612 | — | 24 Oct 2022 | |
| T. Rowe Price Investment Management, Inc. |
13F
13D/G
|
Company |
3.3%
from 13D/G
|
9,217,097
|
$51,063,000 | — | 30 Sep 2025 | |
| David R. Liu |
3/4/5
|
10%+ Owner |
11%
|
20,240,945
|
$50,920,145 | +$163,017 | 30 Jun 2025 | |
| ARCH Venture Partners X, LLC |
3/4/5
|
10%+ Owner |
10%
|
18,486,894
|
$73,876,172 | +$9,999,990 | 01 Aug 2025 | |
| ARCH Venture Partners XII, LLC |
3/4/5
|
10%+ Owner |
10%
|
18,486,894
|
$73,876,172 | +$9,999,990 | 01 Aug 2025 | |
| GV 2021 GP, L.L.C. |
3/4/5
|
10%+ Owner |
1.8%
|
3,262,440
|
$10,766,052 | +$4,950,000 | 01 Aug 2025 | |
| Alphabet Inc. |
13F
|
Company |
9.1%
|
16,562,498
|
$91,756,239 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
3.1%
|
5,650,859
|
$31,305,758 | — | 30 Sep 2025 | |
| ARK Investment Management LLC |
13F
|
Company |
3%
|
5,477,851
|
$30,347,295 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
2.7%
|
4,921,865
|
$27,267,132 | — | 30 Sep 2025 | |
| FARALLON CAPITAL MANAGEMENT LLC |
13F
|
Company |
2.6%
|
4,750,000
|
$26,315,000 | — | 30 Sep 2025 | |
| Sumitomo Mitsui Trust Group, Inc. |
13F
|
Company |
2%
|
3,629,924
|
$20,109,779 | — | 30 Sep 2025 | |
| Amova Asset Management Americas, Inc. |
13F
|
Company |
2%
|
3,629,924
|
$20,037,180 | — | 30 Sep 2025 | |
| Casdin Capital, LLC |
13F
|
Company |
1.7%
|
3,167,175
|
$17,546,150 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
1.7%
|
3,002,482
|
$16,633,750 | — | 30 Sep 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
1.7%
|
3,000,000
|
$16,620,000 | — | 30 Sep 2025 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
1.2%
|
2,215,852
|
$12,275,820 | — | 30 Sep 2025 | |
| MWG Management Ltd. |
13F
|
Company |
0.99%
|
1,792,210
|
$9,928,843 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.97%
|
1,766,896
|
$9,790,782 | — | 30 Sep 2025 | |
| EcoR1 Capital, LLC |
13F
|
Company |
0.85%
|
1,543,326
|
$8,550,026 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.78%
|
1,418,463
|
$7,858,285 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
0.71%
|
1,296,626
|
$7,183,308 | — | 30 Sep 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.62%
|
1,134,670
|
$6,286,072 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.5%
|
900,142
|
$4,986,786 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.42%
|
771,361
|
$4,273,340 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.42%
|
762,078
|
$4,221,912 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.4%
|
731,004
|
$4,049,763 | — | 30 Sep 2025 | |
| Greenwich Wealth Management LLC |
13F
|
Company |
0.4%
|
720,001
|
$3,989,000 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.33%
|
607,989
|
$3,368,259 | — | 30 Sep 2025 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
0.33%
|
593,039
|
$3,285,433 | — | 30 Sep 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.32%
|
584,424
|
$3,237,709 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.32%
|
573,158
|
$3,175,295 | — | 30 Sep 2025 | |
| MOORE CAPITAL MANAGEMENT, LP |
13F
|
Company |
0.28%
|
500,000
|
$2,770,000 | — | 30 Sep 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.25%
|
447,667
|
$2,480,075 | — | 30 Sep 2025 | |
| AQR CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.23%
|
414,211
|
$2,294,729 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.23%
|
410,736
|
$2,275,477 | — | 30 Sep 2025 | |
| Bollard Group LLC |
13F
|
Company |
0.2%
|
361,136
|
$2,001,000 | — | 30 Sep 2025 | |
| HighTower Advisors, LLC |
13F
|
Company |
0.18%
|
333,755
|
$1,849,003 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.17%
|
304,773
|
$1,688,443 | — | 30 Sep 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.12%
|
225,843
|
$1,251,170 | — | 30 Sep 2025 | |
| HRT FINANCIAL LP |
13F
|
Company |
0.12%
|
221,464
|
$1,226,000 | — | 30 Sep 2025 | |
| CHELSEA COUNSEL CO |
13F
|
Company |
0.11%
|
208,210
|
$1,153,484 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.11%
|
205,325
|
$1,137,501 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.11%
|
197,729
|
$1,095,421 | — | 30 Sep 2025 | |
| WELLS FARGO & COMPANY/MN |
13F
|
Company |
0.11%
|
197,014
|
$1,091,458 | — | 30 Sep 2025 | |
| Green Alpha Advisors, LLC |
13F
|
Company |
0.1%
|
190,353
|
$1,054,556 | — | 30 Sep 2025 | |
| Man Group plc |
13F
|
Company |
0.1%
|
189,588
|
$1,050,318 | — | 30 Sep 2025 |
Institutional Holders of Prime Medicine, Inc. - COMMON STOCK (PRME) as of Q4 2025
As of 31 Dec 2025,
Prime Medicine, Inc. - COMMON STOCK (PRME) was held by
182 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
97,023,671 shares.
The largest 10 holders included
Alphabet Inc., BlackRock, Inc., VANGUARD GROUP INC, T. Rowe Price Investment Management, Inc., ARK Investment Management LLC, STATE STREET CORP, Sumitomo Mitsui Trust Group, Inc., Amova Asset Management Americas, Inc., Casdin Capital, LLC, and Balyasny Asset Management L.P..
This page lists
182
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
165
Q4 2025 holders
182
Holder diff
17
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.