Latest Period
Q1 2026
Security Snapshot
Prime Medicine, Inc. - COMMON STOCK (PRME) Institutional Ownership
CUSIP: 74168J101
13F Institutional Holders and Ownership History from Q4 2022 to Q1 2026
Institutions Reporting
189
Shares (Excl. Options)
98,288,858
Price
$3.48
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- Security type / class
- Equity / COMMON STOCK
- Symbol
- PRME on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 98,288,858
- Total 13F value
- $341,719,968
- Portfolio coverage rank
- 0%
- Share change
- +3,381,815
- Value change
- +$11,657,337
- Number of holders
- 189
- Shares outstanding
- 181,672,212
- SEC-reported price per share
- $3.30
- Insider filing price
- $3.30
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- PRME - Prime Medicine, Inc. - COMMON STOCK is tracked under CUSIP 74168J101.
- 189 institutions reported positions in Q1 2026.
- 5 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 182 to 189 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $336,614,188 to $341,719,968.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 189 institutions filings for Q1 2026.
Security key
74168J101
Latest holder period
Q1 2026
13F holders
189
13D/G owners
5
CIK / CUSIP context first
Open Q1 2026 holders
PRME full holder history
Prime Medicine, Inc. SEC filings
Prime Medicine, Inc. company facts
Prime Medicine, Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 74168J101:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
5
Security
PRME
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ARCH Venture Fund XII, L.P. | 10% | $80,853,607 | 18,587,036 | Robert Nelsen | 07 Aug 2025 | |||
| GV 2019, L.P. | 12% | $91,756,239 | 16,562,498 | Alphabet Holdings LLC | 30 Sep 2025 | |||
| FMR LLC | 3.8% | $37,294,150 | 6,731,796 | FMR LLC | 30 Sep 2025 | |||
| Newpath Partners, L.P. | 4.7% | $9,769,086 | 6,105,679 | Newpath Partners, L.P. | 31 Dec 2024 | |||
| T. Rowe Price Investment Management, Inc. | 3.3% | -40% | $25,659,383 | -$13,874,784 | 5,995,183 | -35% | T. Rowe Price Investment Management, Inc. | 31 Dec 2025 |
As of 31 Mar 2026, 189 institutional investors reported holding 98,288,858 shares of Prime Medicine, Inc. - COMMON STOCK (PRME). This represents 54% of the company’s total 181,672,212 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
46%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Alphabet Inc. | 9.1% | 16,562,498 | 0% | 1.4% | $57,637,493 |
| BlackRock, Inc. | 4.7% | 8,501,708 | +2.8% | 0% | $29,585,944 |
| STATE STREET CORP | 3.5% | 6,345,125 | +25% | 0% | $22,081,035 |
| ARK Investment Management LLC | 3.4% | 6,246,827 | +16% | 0.17% | $21,738,957 |
| T. Rowe Price Investment Management, Inc. | 3% | 5,481,893 | -8.6% | 0.01% | $19,077,000 |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.5% | 4,474,162 | 0% | 0% | $15,570,084 |
| Balyasny Asset Management L.P. | 2.3% | 4,123,365 | +32% | 0.03% | $14,349,310 |
| Casdin Capital, LLC | 1.7% | 3,167,175 | 0% | 0.83% | $11,021,769 |
| Woodline Partners LP | 1.7% | 3,003,313 | +0.02% | 0.04% | $10,451,529 |
| Amova Asset Management Americas, Inc. | 1.6% | 2,940,793 | -9.4% | 0.14% | $10,204,552 |
| Sumitomo Mitsui Trust Group, Inc. | 1.6% | 2,940,793 | -9.4% | 0.01% | $10,233,960 |
| UBS Group AG | 1.6% | 2,888,418 | +18% | 0% | $10,051,695 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.5% | 2,743,700 | +4.4% | 0% | $9,550,585 |
| ADAR1 Capital Management, LLC | 1.1% | 1,973,282 | 0.42% | $6,867,021 | |
| FMR LLC | 0.97% | 1,769,476 | -19% | 0% | $6,157,775 |
| Redmile Group, LLC | 0.88% | 1,590,832 | 0.37% | $5,536,095 | |
| TWO SIGMA INVESTMENTS, LP | 0.87% | 1,572,811 | -3.5% | 0% | $5,473,382 |
| D. E. Shaw & Co., Inc. | 0.77% | 1,393,621 | -10% | 0% | $4,849,802 |
| FARALLON CAPITAL MANAGEMENT LLC | 0.68% | 1,240,843 | 0% | 0.03% | $4,318,134 |
| GOLDMAN SACHS GROUP INC | 0.53% | 970,425 | -45% | 0% | $3,377,079 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.5% | 917,212 | -2.1% | 0% | $3,191,898 |
| NORTHERN TRUST CORP | 0.49% | 886,716 | +5.3% | 0% | $3,085,771 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 0.47% | 862,204 | 0% | 0% | $3,000,470 |
| JPMORGAN CHASE & CO | 0.46% | 844,154 | +94% | 0% | $2,659,085 |
| Greenwich Wealth Management LLC | 0.41% | 750,001 | +1.4% | 0.11% | $2,610,000 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
14
Latest
Q1 2026
Rows shown
1-14 of 14
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 98,288,858 | $341,719,968 | +$11,657,337 | $3.48 | 189 |
| 2025 Q4 | 97,023,671 | $336,614,188 | +$756,626 | $3.47 | 182 |
| 2025 Q3 | 92,347,818 | $511,536,971 | +$186,859,809 | $5.54 | 165 |
| 2025 Q2 | 58,654,950 | $144,864,309 | -$2,708,584 | $2.47 | 118 |
| 2025 Q1 | 60,327,480 | $120,048,763 | -$9,144,075 | $1.99 | 121 |
| 2024 Q4 | 64,302,617 | $187,767,212 | -$16,411,951 | $2.92 | 128 |
| 2024 Q3 | 68,711,037 | $265,862,243 | -$1,687,770 | $3.87 | 113 |
| 2024 Q2 | 68,888,470 | $353,995,003 | +$8,574,594 | $5.14 | 119 |
| 2024 Q1 | 66,659,039 | $466,578,147 | +$125,445,462 | $7.00 | 112 |
| 2023 Q4 | 48,691,116 | $431,437,073 | -$10,408,984 | $8.86 | 102 |
| 2023 Q3 | 49,517,421 | $472,282,828 | +$28,502,950 | $9.54 | 82 |
| 2023 Q2 | 46,131,758 | $675,732,293 | +$67,078,075 | $14.65 | 77 |
| 2023 Q1 | 41,738,575 | $512,085,492 | +$2,897,210 | $12.30 | 73 |
| 2022 Q4 | 41,322,385 | $767,784,036 | +$767,085,261 | $18.58 | 65 |