Prime Medicine, Inc. - COMMON STOCK (PRME)

Historical Holders from Q4 2022 to Q4 2025

Symbol
PRME on Nasdaq
Type / Class
Equity / COMMON STOCK
Shares outstanding
174,282,170
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares, excl. options
92,347,242
Holdings value
$511,533,781
% of all portfolios
0%
Number of holders
163
Number of buys
114
Number of sells
37
Average buys %
+0%
Average sells %
-0%
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Prime Medicine, Inc. - COMMON STOCK (PRME) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ARCH Venture Fund XII, L.P. 10% $80,853,607 18,587,036 Robert Nelsen 07 Aug 2025
GV 2019, L.P. 12% $91,756,239 16,562,498 Alphabet Holdings LLC 30 Sep 2025
T. Rowe Price Investment Management, Inc. 5.3% $51,172,731 9,236,955 T. Rowe Price Investment Management, Inc. 30 Sep 2025
FMR LLC 3.8% $37,294,150 6,731,796 FMR LLC 30 Sep 2025
Newpath Partners, L.P. 4.7% $9,769,086 6,105,679 Newpath Partners, L.P. 31 Dec 2024
As of 30 Sep 2025 Prime Medicine, Inc. - COMMON STOCK (PRME) has 163 institutional shareholders that have filed 13F forms with the Securities Exchange Commission (SEC). These institutions hold a total of 92,347,242 shares of 174,282,170 outstanding shares and own 53% of the company stock as of 30 Sep 2025.

Top 25 institutional shareholders of Prime Medicine, Inc. - COMMON STOCK (PRME) own 47% of the company based on 13F filings as of 30 Sep 2025

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
Alphabet Inc. 9.5% 16,562,498 +10% 3.8% $91,756,239
T. Rowe Price Investment Management, Inc. 5.3% 9,217,097 +42% 0.03% $51,063,000
BlackRock, Inc. 3.2% 5,650,859 +26% 0% $31,305,758
ARK Investment Management LLC 3.1% 5,477,851 +136% 0.18% $30,347,295
VANGUARD GROUP INC 2.8% 4,921,865 +36% 0% $27,267,132
FARALLON CAPITAL MANAGEMENT LLC 2.7% 4,750,000 +533% 0.15% $26,315,000
Amova Asset Management Americas, Inc. 2.1% 3,629,924 +128% 0.19% $20,037,180
Sumitomo Mitsui Trust Group, Inc. 2.1% 3,629,924 +128% 0.01% $20,109,779
Casdin Capital, LLC 1.8% 3,167,175 +102% 1.5% $17,546,150
Woodline Partners LP 1.7% 3,002,482 0.08% $16,633,750
RA CAPITAL MANAGEMENT, L.P. 1.7% 3,000,000 0.2% $16,620,000
FMR LLC 1.6% 2,813,075 -25% 0% $15,584,435
D. E. Shaw & Co., Inc. 1.3% 2,215,852 0.01% $12,275,820
MWG Management Ltd. 1% 1,792,210 0% 12% $9,928,843
GEODE CAPITAL MANAGEMENT, LLC 1% 1,766,896 +17% 0% $9,790,782
EcoR1 Capital, LLC 0.89% 1,543,326 0.41% $8,550,026
MILLENNIUM MANAGEMENT LLC 0.81% 1,418,463 +858% 0.01% $7,858,285
STATE STREET CORP 0.74% 1,296,626 +4.6% 0% $7,183,308
RENAISSANCE TECHNOLOGIES LLC 0.65% 1,134,670 +408% 0.01% $6,286,072
CITADEL ADVISORS LLC 0.52% 900,142 +73% 0% $4,986,786
ADAGE CAPITAL PARTNERS GP, L.L.C. 0.44% 771,361 0.01% $4,273,340
Invesco Ltd. 0.44% 762,078 +5478% 0% $4,221,912
MORGAN STANLEY 0.42% 731,004 +24% 0% $4,049,763
Greenwich Wealth Management LLC 0.41% 720,001 -15% 0.2% $3,989,000
NORTHERN TRUST CORP 0.35% 607,989 +19% 0% $3,368,259

Institutional Holders of Prime Medicine, Inc. - COMMON STOCK (PRME) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price Investors
2025 Q4 1,111 $3,855 +$385 $3.47 2
2025 Q3 92,347,242 $511,533,781 +$186,777,668 $5.54 163
2025 Q2 58,654,950 $144,864,309 -$2,708,584 $2.47 118
2025 Q1 60,327,480 $120,048,763 -$9,144,075 $1.99 121
2024 Q4 64,302,617 $187,767,212 -$16,411,951 $2.92 128
2024 Q3 68,711,037 $265,862,243 -$1,687,770 $3.87 113
2024 Q2 68,888,470 $353,995,003 +$8,574,594 $5.14 119
2024 Q1 66,659,039 $466,578,147 +$125,445,462 $7.00 112
2023 Q4 48,691,116 $431,437,073 -$10,408,984 $8.86 102
2023 Q3 49,517,421 $472,282,828 +$28,502,950 $9.54 82
2023 Q2 46,131,758 $675,732,293 +$67,078,075 $14.65 77
2023 Q1 41,738,575 $512,085,492 +$2,897,210 $12.30 73
2022 Q4 41,322,385 $767,784,036 +$767,085,261 $18.58 65