- Type / Class
- Equity / COMMON STOCK
- Shares outstanding
- 181,672,212
- Total 13F shares
- 92,347,818
- Share change
- +33,667,998
- Total reported value
- $511,536,971
- Put/Call ratio
- 71%
- Price per share
- $5.54
- Number of holders
- 165
- Value change
- +$186,859,809
- Number of buys
- 115
- Number of sells
- 37
Quarterly Holders Quick Answers
What is CUSIP 74168J101?
CUSIP 74168J101 identifies PRME - Prime Medicine, Inc. - COMMON STOCK in SEC institutional holdings data.
Need full ownership history?
Open the full security ownership history page.
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- Latest 13F filings for newly reported positions across managers.
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Jump to adjacent filing periods for faster comparison and easier crawl discovery.
Recent filing periods for CUSIP 74168J101:
Top shareholders of PRME - Prime Medicine, Inc. - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| GV 2019 GP, L.L.C. |
3/4/5
|
10%+ Owner |
—
class O/S missing
|
11,862,498
|
$177,594,643 | — | 20 Jun 2023 | |
| FMR LLC |
3/4/5
13D/G
13F
|
Other* · Company |
3.8%
from 13D/G
|
8,462,946
|
$126,699,612 | — | 24 Oct 2022 | |
| GV 2019, L.P. |
13D/G
|
Alphabet Holdings LLC |
12%
|
16,562,498
|
$91,756,239 | $0 | 30 Sep 2025 | |
| ARCH Venture Fund XII, L.P. |
13D/G
|
Robert Nelsen |
10%
|
18,587,036
|
$80,853,607 | $0 | 07 Aug 2025 | |
| Robert Nelsen |
3/4/5
|
Director, 10%+ Owner |
—
mixed-class rows
|
18,547,974
mixed-class rows
|
$73,946,120 | +$9,999,990 | 01 Aug 2025 | |
| ARCH Venture Partners X, LLC |
3/4/5
|
10%+ Owner |
10%
|
18,486,894
|
$73,876,172 | +$9,999,990 | 01 Aug 2025 | |
| ARCH Venture Partners XII, LLC |
3/4/5
|
10%+ Owner |
10%
|
18,486,894
|
$73,876,172 | +$9,999,990 | 01 Aug 2025 | |
| David R. Liu |
3/4/5
|
10%+ Owner |
11%
|
20,240,945
|
$50,920,145 | +$163,017 | 30 Jun 2025 | |
| Alphabet Inc. |
13F
|
Company |
8.3%
|
15,062,498
|
$37,204,370 | — | 30 Jun 2025 | |
| GV 2023 GP, L.L.C. |
3/4/5
|
Member of 10% Group |
—
class O/S missing
|
3,200,000
|
$20,000,000 | — | 20 Feb 2024 | |
| Keith Michael Gottesdiener |
3/4/5
|
Exhibit 24 - Power of Attorney; Title: President and Chief Executive Officer, Director |
—
mixed-class rows
|
3,343,337
mixed-class rows
|
$19,020,856 | — | 08 May 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
3.6%
|
6,484,787
|
$16,018,000 | — | 30 Jun 2025 | |
| BlackRock, Inc. |
13F
|
Company |
2.5%
|
4,485,828
|
$11,079,995 | — | 30 Jun 2025 | |
| GV 2021 GP, L.L.C. |
3/4/5
|
10%+ Owner |
1.8%
|
3,262,440
|
$10,766,052 | +$4,950,000 | 01 Aug 2025 | |
| Newpath Partners, L.P. |
13D/G
|
— |
4.7%
|
6,105,679
|
$9,769,086 | $0 | 31 Dec 2024 | |
| VANGUARD GROUP INC |
13F
|
Company |
2%
|
3,627,510
|
$8,959,950 | — | 30 Jun 2025 | |
| ARK Investment Management LLC |
13F
|
Company |
1.3%
|
2,322,669
|
$5,736,992 | — | 30 Jun 2025 | |
| Redmile Group, LLC |
13F
|
Company |
1.1%
|
2,074,350
|
$5,123,645 | — | 30 Jun 2025 | |
| MWG Management Ltd. |
13F
|
Company |
0.99%
|
1,792,210
|
$4,426,759 | — | 30 Jun 2025 | |
| Sumitomo Mitsui Trust Group, Inc. |
13F
|
Company |
0.88%
|
1,594,518
|
$3,938,459 | — | 30 Jun 2025 | |
| Amova Asset Management Americas, Inc. |
13F
|
Company |
0.87%
|
1,589,117
|
$3,893,337 | — | 30 Jun 2025 | |
| Casdin Capital, LLC |
13F
|
Company |
0.86%
|
1,567,175
|
$3,870,922 | — | 30 Jun 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.83%
|
1,510,749
|
$3,732,447 | — | 30 Jun 2025 | |
| STATE STREET CORP |
13F
|
Company |
0.68%
|
1,239,337
|
$3,061,162 | — | 30 Jun 2025 | |
| Greenwich Wealth Management LLC |
13F
|
Company |
0.47%
|
846,201
|
$2,090,000 | — | 30 Jun 2025 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
0.45%
|
818,518
|
$2,021,736 | — | 30 Jun 2025 | |
| FARALLON CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.41%
|
750,000
|
$1,852,500 | — | 30 Jun 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.32%
|
587,676
|
$1,451,561 | — | 30 Jun 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.29%
|
521,508
|
$1,288,124 | — | 30 Jun 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.29%
|
518,628
|
$1,281,011 | — | 30 Jun 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.28%
|
512,234
|
$1,265,217 | — | 30 Jun 2025 | |
| MOORE CAPITAL MANAGEMENT, LP |
13F
|
Company |
0.28%
|
500,000
|
$1,235,000 | — | 30 Jun 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.27%
|
482,728
|
$1,192,338 | — | 30 Jun 2025 | |
| AQR CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.23%
|
424,355
|
$1,048,157 | — | 30 Jun 2025 | |
| FRED ALGER MANAGEMENT, LLC |
13F
|
Company |
0.21%
|
383,194
|
$946,489 | — | 30 Jun 2025 | |
| Bollard Group LLC |
13F
|
Company |
0.2%
|
361,136
|
$892,000 | — | 30 Jun 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.14%
|
258,423
|
$638,305 | — | 30 Jun 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.12%
|
223,400
|
$551,798 | — | 30 Jun 2025 | |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.12%
|
214,800
|
$530,556 | — | 30 Jun 2025 | |
| CHELSEA COUNSEL CO |
13F
|
Company |
0.11%
|
208,210
|
$514,279 | — | 30 Jun 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.11%
|
207,894
|
$513,498 | — | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.11%
|
207,008
|
$511,310 | — | 30 Jun 2025 | |
| UBS Group AG |
13F
|
Company |
0.11%
|
195,327
|
$482,458 | — | 30 Jun 2025 | |
| SIMPLEX TRADING, LLC |
13F
|
Company |
0.11%
|
193,615
|
$478,000 | — | 30 Jun 2025 | |
| Palumbo Wealth Management LLC |
13F
|
Company |
0.1%
|
183,358
|
$452,895 | — | 30 Jun 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
0.09%
|
167,420
|
$413,527 | — | 30 Jun 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.09%
|
162,052
|
$400,267 | — | 30 Jun 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.08%
|
147,996
|
$365,550 | — | 30 Jun 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.08%
|
144,511
|
$356,943 | — | 30 Jun 2025 | |
| LEVIN CAPITAL STRATEGIES, L.P. |
13F
|
Company |
0.08%
|
140,000
|
$345,800 | — | 30 Jun 2025 |
Institutional Holders of Prime Medicine, Inc. - COMMON STOCK (PRME) as of Q3 2025
As of 30 Sep 2025,
Prime Medicine, Inc. - COMMON STOCK (PRME) was held by
165 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
92,347,818 shares.
The largest 10 holders included
Alphabet Inc., T. Rowe Price Investment Management, Inc., BlackRock, Inc., ARK Investment Management LLC, VANGUARD GROUP INC, FARALLON CAPITAL MANAGEMENT LLC, Sumitomo Mitsui Trust Group, Inc., Amova Asset Management Americas, Inc., Casdin Capital, LLC, and Woodline Partners LP.
This page lists
165
institutional shareholders reporting positions in this security
for the Q3 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
118
Q3 2025 holders
165
Holder diff
47
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 Value $ | Q3 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.