| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 9.6% | $9,198,699 | 5,859,044 | TANG CAPITAL MANAGEMENT, LLC | 03 Mar 2025 | |||
| CITADEL ADVISORS LLC | 5% | +2% | $3,711,402 | +$5,414 | 3,042,133 | +0.15% | Kenneth Griffin | 02 Feb 2026 |
| VANGUARD GROUP INC | 4.9% | $3,482,724 | 3,002,348 | The Vanguard Group | 30 Jun 2025 | |||
| Redmile Group, LLC | 4.8% | $4,545,900 | 2,895,478 | Redmile Group, LLC | 31 Dec 2024 | |||
| BlackRock, Inc. | 3.4% | $2,440,674 | 2,104,574 | BlackRock, Inc. | 30 Jun 2025 | |||
| Woodline Partners LP | 3.3% | -57% | $2,471,953 | -$3,023,924 | 2,026,191 | -55% | Woodline Partners LP | 31 Dec 2025 |
| MORGAN STANLEY | 0.9% | -87% | $861,460 | -$5,043,529 | 545,228 | -85% | Morgan Stanley | 31 Dec 2025 |
| FMR LLC | 0.2% | $207,230 | 131,993 | FMR LLC | 28 Feb 2025 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 0.1% | $137,648 | 87,674 | T. Rowe Price Associates, Inc. | 31 Mar 2025 | |||
| Point72 Asset Management, L.P. | 0.1% | -94% | $56,775 | -$4,926,946 | 46,537 | -99% | Point72 Asset Management, L.P. | 31 Dec 2025 |
As of 31 Dec 2025, 92 institutional investors reported holding 46,413,510 shares of PLIANT THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (PLRX). This represents 76% of the company’s total 61,399,727 outstanding shares.
The largest institutional shareholders of PLIANT THERAPEUTICS, INC. - Common Stock, par value $0.0001 per share (PLRX) together control 64% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 10% | 6,143,132 | +2.3% | 0.37% | $7,494,621 |
| Blue Owl Capital Holdings LP | 4.8% | 2,969,199 | 0% | 1.1% | $3,622,423 |
| VANGUARD GROUP INC | 4.6% | 2,818,241 | +1.5% | 0% | $3,438,255 |
| CITADEL ADVISORS LLC | 4.2% | 2,583,332 | +10% | 0% | $3,151,665 |
| ACADIAN ASSET MANAGEMENT LLC | 3.9% | 2,364,669 | -0.21% | 0% | $2,879,000 |
| Woodline Partners LP | 3.3% | 2,026,191 | -55% | 0.01% | $2,471,953 |
| Monaco Asset Management SAM | 3.2% | 1,938,747 | +136% | 0.7% | $2,365,271 |
| Redmile Group, LLC | 2.6% | 1,616,228 | +1.5% | 0.15% | $1,971,798 |
| Prosight Management, LP | 2.5% | 1,555,744 | +7494% | 0.39% | $1,898,008 |
| BML Capital Management, LLC | 2.5% | 1,546,137 | 0% | 1.7% | $1,886,287 |
| TWO SIGMA ADVISERS, LP | 2% | 1,245,600 | +16% | 0% | $1,519,632 |
| JPMORGAN CHASE & CO | 2% | 1,212,875 | -43% | 0% | $1,479,707 |
| MARSHALL WACE, LLP | 1.8% | 1,080,128 | +261% | 0% | $1,317,756 |
| BlackRock, Inc. | 1.7% | 1,073,272 | -24% | 0% | $1,309,392 |
| UBS Group AG | 1.7% | 1,062,615 | -20% | 0% | $1,296,390 |
| RENAISSANCE TECHNOLOGIES LLC | 1.7% | 1,045,818 | +3.4% | 0% | $1,275,898 |
| Centiva Capital, LP | 1.6% | 1,000,000 | 0.07% | $1,220,000 | |
| TWO SIGMA INVESTMENTS, LP | 1.6% | 953,293 | +22% | 0% | $1,163,017 |
| Peapod Lane Capital LLC | 1.4% | 886,374 | -19% | 0.92% | $1,081,376 |
| Eversept Partners, LP | 1.4% | 842,023 | +2.1% | 0.06% | $1,027,268 |
| BANK OF AMERICA CORP /DE/ | 1.2% | 711,777 | +0.53% | 0% | $868,368 |
| JANE STREET GROUP, LLC | 1.1% | 653,774 | +72% | 0% | $797,605 |
| GSA CAPITAL PARTNERS LLP | 1% | 623,698 | +288% | 0.07% | $761,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.97% | 592,696 | +0.9% | 0% | $723,448 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0.91% | 556,938 | +52% | 0% | $679,464 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 46,413,510 | $57,202,773 | -$7,124,088 | $1.22 | 92 |
| 2025 Q3 | 50,406,732 | $74,592,710 | +$1,536,230 | $1.48 | 97 |
| 2025 Q2 | 51,491,424 | $59,725,484 | -$8,565,167 | $1.16 | 112 |
| 2025 Q1 | 57,869,854 | $78,126,006 | -$216,549,992 | $1.35 | 138 |
| 2024 Q4 | 64,754,179 | $852,599,671 | +$21,507,892 | $13.17 | 158 |
| 2024 Q3 | 63,483,171 | $714,277,363 | -$5,607,911 | $11.21 | 149 |
| 2024 Q2 | 63,896,951 | $686,885,070 | -$18,557,994 | $10.75 | 141 |
| 2024 Q1 | 65,187,064 | $971,256,923 | +$41,504,855 | $14.90 | 133 |
| 2023 Q4 | 62,712,668 | $1,135,768,923 | +$100,850,737 | $18.11 | 133 |
| 2023 Q3 | 60,161,028 | $1,043,150,835 | +$29,447,949 | $17.34 | 134 |
| 2023 Q2 | 58,042,121 | $1,051,734,729 | +$9,423,269 | $18.12 | 141 |
| 2023 Q1 | 56,237,135 | $1,495,380,265 | +$312,862,520 | $26.60 | 143 |
| 2022 Q4 | 44,702,851 | $864,087,630 | -$14,811,927 | $19.33 | 123 |
| 2022 Q3 | 45,386,319 | $948,113,021 | +$327,405,105 | $20.89 | 107 |
| 2022 Q2 | 30,133,558 | $241,439,678 | -$11,245,591 | $8.01 | 81 |
| 2022 Q1 | 31,426,255 | $220,339,413 | +$4,111,275 | $7.01 | 85 |
| 2021 Q4 | 30,850,148 | $416,473,043 | +$5,468,177 | $13.50 | 81 |
| 2021 Q3 | 30,380,086 | $512,798,759 | -$14,863,235 | $16.88 | 75 |
| 2021 Q2 | 30,676,131 | $893,270,740 | -$1,364,693 | $29.12 | 80 |
| 2021 Q1 | 30,719,770 | $1,208,139,215 | +$88,069,181 | $39.33 | 76 |
| 2020 Q4 | 28,511,470 | $647,801,804 | +$7,265,154 | $22.72 | 57 |
| 2020 Q3 | 28,195,401 | $635,735,229 | +$17,040,139 | $22.65 | 53 |
| 2020 Q2 | 26,908,341 | $868,442,000 | +$868,442,000 | $32.46 | 36 |