| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 9.6% | $9.2M | 5.86M | TANG CAPITAL MANAGEMENT, LLC | 03 Mar 2025 | |||
| Woodline Partners LP | 7.3% | $6.67M | 4.5M | Woodline Partners LP | 30 Sep 2025 | |||
| Point72 Asset Management, L.P. | 6.7% | $6.54M | 4.09M | Point72 Asset Management, L.P. | 27 Aug 2025 | |||
| MORGAN STANLEY | 6.1% | $5.27M | 3.74M | Morgan Stanley | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 4.89% | $3.48M | 3M | The Vanguard Group | 30 Jun 2025 | |||
| Redmile Group, LLC | 4.8% | $4.55M | 2.9M | Redmile Group, LLC | 31 Dec 2024 | |||
| BlackRock, Inc. | 3.4% | $2.44M | 2.1M | BlackRock, Inc. | 30 Jun 2025 | |||
| FMR LLC | 0.2% | $207K | 132K | FMR LLC | 28 Feb 2025 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 0.1% | $138K | 87.7K | T. Rowe Price Associates, Inc. | 31 Mar 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 50.4M | $74.6M | +$1.54M | $1.48 | 97 |
| 2025 Q2 | 51.5M | $59.7M | -$8.57M | $1.16 | 112 |
| 2025 Q1 | 57.9M | $78.1M | -$217M | $1.35 | 138 |
| 2024 Q4 | 64.8M | $853M | +$21.5M | $13.17 | 158 |
| 2024 Q3 | 63.5M | $714M | -$5.61M | $11.21 | 149 |
| 2024 Q2 | 63.9M | $687M | -$18.6M | $10.75 | 141 |
| 2024 Q1 | 65.2M | $971M | +$41.5M | $14.90 | 133 |
| 2023 Q4 | 62.7M | $1.14B | +$101M | $18.11 | 133 |
| 2023 Q3 | 60.2M | $1.04B | +$29.4M | $17.34 | 134 |
| 2023 Q2 | 58M | $1.05B | +$9.42M | $18.12 | 141 |
| 2023 Q1 | 56.2M | $1.5B | +$313M | $26.60 | 143 |
| 2022 Q4 | 44.7M | $864M | -$14.8M | $19.33 | 123 |
| 2022 Q3 | 45.4M | $948M | +$327M | $20.89 | 107 |
| 2022 Q2 | 30.1M | $241M | -$11.2M | $8.01 | 81 |
| 2022 Q1 | 31.4M | $220M | +$4.11M | $7.01 | 85 |
| 2021 Q4 | 30.9M | $416M | +$5.47M | $13.50 | 81 |
| 2021 Q3 | 30.4M | $513M | -$14.9M | $16.88 | 75 |
| 2021 Q2 | 30.7M | $893M | -$1.36M | $29.12 | 80 |
| 2021 Q1 | 30.7M | $1.21B | +$88.1M | $39.33 | 76 |
| 2020 Q4 | 28.5M | $648M | +$7.27M | $22.72 | 57 |
| 2020 Q3 | 28.2M | $636M | +$17M | $22.65 | 53 |
| 2020 Q2 | 26.9M | $868M | +$868M | $32.46 | 36 |