Security Snapshot

Personalis, Inc. - COMMON STOCK (PSNL) Institutional Ownership

CUSIP: 71535D106

13F Institutional Holders and Ownership History from Q2 2019 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

125

Shares (Excl. Options)

81,001,611

Price

$7.96

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Type / Class
Equity / COMMON STOCK
Symbol
PSNL on Nasdaq
Shares outstanding
105,735,356
Price per share
$6.37
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
81,001,611
Total reported value
$644,778,177
% of total 13F portfolios
0%
Share change
+15,960,629
Value change
+$129,305,525
Number of holders
125
Price from insider filings
$6.37
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

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Quick Takeaways

  • PSNL - Personalis, Inc. - COMMON STOCK is tracked under CUSIP 71535D106.
  • 125 institutions reported positions in Q4 2025.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 125 to 6 between Q4 2025 and Q1 2026.
  • Reported value moved from $644,778,177 to $3,962,025.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 125 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 71535D106?
CUSIP 71535D106 identifies PSNL - Personalis, Inc. - COMMON STOCK in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of Personalis, Inc. - COMMON STOCK (PSNL) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Merck & Co., Inc. 16% $53,792,132 14,044,943 Merck & Co., Inc. 19 Dec 2024
Tempus AI, Inc. 14% $58,553,040 12,868,800 Eric Lefkofsky 11 Sep 2025
KEYWELL BRADLEY A 7.6% $49,211,559 12,848,971 Bradley A. Keywell 17 Jan 2025
Red Sky Ventures LLC 4.7% -17% $52,546,773 -$9,366,221 8,059,321 -15% Red Sky Ventures LLC 30 Sep 2025
ARK Investment Management LLC 8.1% -14% $27,530,795 +$1,580,878 7,188,197 +6.1% ARK Investment Management LLC 31 Mar 2025
AMERIPRISE FINANCIAL INC 7.1% $53,880,884 6,287,151 Ameriprise Financial, Inc. 31 Dec 2025
T. Rowe Price Investment Management, Inc. 4.5% -63% $30,312,846 -$38,366,225 4,758,091 -56% T. Rowe Price Investment Management, Inc. 31 Mar 2026
HIRSCHMAN ORIN 3.8% -38% $27,205,633 -$6,982,468 3,416,720 -20% Orin Hirschman 31 Dec 2025
BlackRock, Inc. 3.5% $11,318,301 2,955,170 BlackRock, Inc. 31 Dec 2024

As of 31 Dec 2025, 125 institutional investors reported holding 81,001,611 shares of Personalis, Inc. - COMMON STOCK (PSNL). This represents 77% of the company’s total 105,735,356 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Personalis, Inc. - COMMON STOCK (PSNL) together control 71% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Merck & Co., Inc. 13% 14,044,943 0% 40% $111,797,746
T. Rowe Price Investment Management, Inc. 10% 10,780,290 +274% 0.05% $85,812,000
LIGHTSPEED MANAGEMENT COMPANY, L.L.C. 7.7% 8,160,734 0% 4.7% $64,959,443
ARK Investment Management LLC 7.5% 7,879,087 -0.39% 0.42% $62,717,533
AMERIPRISE FINANCIAL INC 5.9% 6,287,151 +2003% 0.01% $50,045,728
BlackRock, Inc. 5% 5,319,508 -5.8% 0% $42,343,284
VANGUARD GROUP INC 3.1% 3,253,797 +8.2% 0% $25,900,225
Aberdeen Group plc 3.1% 3,249,895 +36% 0.04% $25,869,164
AIGH Capital Management LLC 2.7% 2,900,000 -25% 6.8% $23,084,000
KENNEDY CAPITAL MANAGEMENT LLC 1.6% 1,712,652 -11% 0.29% $13,632,710
Blue Water Life Science Advisors, LP 1.6% 1,676,300 0% 8.4% $13,343,348
PRICE T ROWE ASSOCIATES INC /MD/ 1.4% 1,448,585 +1332% 0% $11,531,000
GEODE CAPITAL MANAGEMENT, LLC 1.2% 1,297,807 -2.7% 0% $10,333,039
STATE STREET CORP 0.99% 1,050,590 +13% 0% $8,362,696
DIMENSIONAL FUND ADVISORS LP 0.93% 983,174 +0.98% 0% $7,826,162
PFM Health Sciences, LP 0.76% 805,817 0.65% $6,414,303
NEXT CENTURY GROWTH INVESTORS LLC 0.59% 624,363 0.35% $4,969,929
Howland Capital Management LLC 0.52% 547,115 +65% 0.17% $4,355,036
Sumitomo Mitsui Trust Group, Inc. 0.49% 518,441 -12% 0% $4,126,790
Amova Asset Management Americas, Inc. 0.49% 518,441 -12% 0.05% $4,126,790
STATE OF MICHIGAN RETIREMENT SYSTEM 0.47% 493,798 0% 0.02% $3,930,632
Portolan Capital Management, LLC 0.36% 379,197 0.16% $3,018,408
FIRST MANHATTAN CO. LLC. 0.35% 373,822 0.01% $2,975,623
NORTHERN TRUST CORP 0.34% 354,918 -9.9% 0% $2,825,147
GOLDMAN SACHS GROUP INC 0.32% 342,475 -40% 0% $2,726,101

Institutional Holders of Personalis, Inc. - COMMON STOCK (PSNL) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 621,913 $3,962,025 +$11,462 $6.37 6
2025 Q4 81,001,611 $644,778,177 +$129,305,525 $7.96 125
2025 Q3 64,702,482 $421,838,154 +$27,589,778 $6.52 107
2025 Q2 60,456,657 $396,611,525 +$44,202,043 $6.56 105
2025 Q1 54,828,320 $192,441,316 +$10,090,223 $3.51 102
2024 Q4 51,601,342 $298,243,551 -$3,572,926 $5.78 107
2024 Q3 29,319,270 $161,516,207 +$43,033,654 $5.38 83
2024 Q2 21,956,574 $25,689,907 -$438,121 $1.17 69
2024 Q1 22,271,019 $33,182,519 +$217,168 $1.49 70
2023 Q4 21,963,535 $46,098,090 -$4,605,029 $2.10 68
2023 Q3 24,787,157 $29,989,246 -$2,223,907 $1.21 63
2023 Q2 26,077,892 $48,999,684 -$2,366,338 $1.88 64
2023 Q1 27,192,343 $74,996,760 +$205,499 $2.76 62
2022 Q4 27,801,895 $55,045,447 -$1,904,858 $1.98 78
2022 Q3 28,367,717 $83,900,229 -$5,226,601 $2.97 77
2022 Q2 29,874,257 $105,564,934 -$15,549,124 $3.45 95
2022 Q1 32,474,275 $265,328,914 -$398,164 $8.19 120
2021 Q4 32,151,998 $456,199,133 +$2,045,734 $14.27 105
2021 Q3 31,406,739 $604,224,567 -$14,422,392 $19.24 116
2021 Q2 31,940,492 $807,886,761 +$23,454,157 $25.30 132
2021 Q1 30,722,882 $755,704,555 +$60,986,103 $24.61 130
2020 Q4 26,591,341 $973,697,818 +$110,231,063 $36.61 128
2020 Q3 25,391,300 $552,000,648 +$128,507,444 $21.67 90
2020 Q2 18,853,701 $244,721,982 +$7,255,056 $12.97 77
2020 Q1 19,072,243 $153,524,384 +$10,223,267 $8.07 65
2019 Q4 17,416,312 $189,722,226 +$10,096,228 $10.90 76
2019 Q3 15,759,296 $231,238,606 -$27,642,247 $14.68 67
2019 Q2 14,833,656 $403,226,244 +$403,226,232 $27.15 67

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