| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Merck & Co., Inc. | 16% | $53,792,132 | 14,044,943 | Merck & Co., Inc. | 19 Dec 2024 | |||
| Tempus AI, Inc. | 14% | $58,553,040 | 12,868,800 | Eric Lefkofsky | 11 Sep 2025 | |||
| KEYWELL BRADLEY A | 7.6% | $49,211,559 | 12,848,971 | Bradley A. Keywell | 17 Jan 2025 | |||
| T. Rowe Price Investment Management, Inc. | 12% | $85,806,796 | 10,780,290 | T. Rowe Price Investment Management, Inc. | 31 Dec 2025 | |||
| Red Sky Ventures LLC | 4.7% | -17% | $52,546,773 | -$9,366,221 | 8,059,321 | -15% | Red Sky Ventures LLC | 30 Sep 2025 |
| ARK Investment Management LLC | 8.1% | -14% | $27,530,795 | +$1,580,878 | 7,188,197 | +6.1% | ARK Investment Management LLC | 31 Mar 2025 |
| AMERIPRISE FINANCIAL INC | 7.1% | $53,880,884 | 6,287,151 | Ameriprise Financial, Inc. | 31 Dec 2025 | |||
| HIRSCHMAN ORIN | 3.8% | -38% | $27,205,633 | -$6,982,468 | 3,416,720 | -20% | Orin Hirschman | 31 Dec 2025 |
| BlackRock, Inc. | 3.5% | $11,318,301 | 2,955,170 | BlackRock, Inc. | 31 Dec 2024 |
As of 31 Dec 2025, 123 institutional investors reported holding 80,989,827 shares of Personalis, Inc. - Common Stock (PSNL). This represents 91% of the company’s total 88,551,423 outstanding shares.
The largest institutional shareholders of Personalis, Inc. - Common Stock (PSNL) together control 85% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Merck & Co., Inc. | 16% | 14,044,943 | 0% | 40% | $111,797,746 |
| T. Rowe Price Investment Management, Inc. | 12% | 10,780,290 | +274% | 0.05% | $85,812,000 |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. | 9.2% | 8,160,734 | 0% | 4.7% | $64,959,443 |
| ARK Investment Management LLC | 8.9% | 7,879,087 | -0.39% | 0.42% | $62,717,533 |
| AMERIPRISE FINANCIAL INC | 7.1% | 6,287,151 | +2003% | 0.01% | $50,045,728 |
| BlackRock, Inc. | 6% | 5,319,508 | -5.8% | 0% | $42,343,284 |
| VANGUARD GROUP INC | 3.7% | 3,253,797 | +8.2% | 0% | $25,900,225 |
| Aberdeen Group plc | 3.7% | 3,249,895 | +36% | 0.04% | $25,869,164 |
| AIGH Capital Management LLC | 3.3% | 2,900,000 | -25% | 6.8% | $23,084,000 |
| KENNEDY CAPITAL MANAGEMENT LLC | 1.9% | 1,712,652 | -11% | 0.29% | $13,632,710 |
| Blue Water Life Science Advisors, LP | 1.9% | 1,676,300 | 0% | 8.4% | $13,343,348 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.6% | 1,448,585 | +1332% | 0% | $11,531,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.5% | 1,297,807 | -2.7% | 0% | $10,333,039 |
| STATE STREET CORP | 1.2% | 1,050,590 | +13% | 0% | $8,362,696 |
| DIMENSIONAL FUND ADVISORS LP | 1.1% | 983,174 | +0.98% | 0% | $7,826,162 |
| PFM Health Sciences, LP | 0.91% | 805,817 | 0.65% | $6,414,303 | |
| NEXT CENTURY GROWTH INVESTORS LLC | 0.71% | 624,363 | 0.35% | $4,969,929 | |
| Howland Capital Management LLC | 0.62% | 547,115 | +65% | 0.17% | $4,355,036 |
| Sumitomo Mitsui Trust Group, Inc. | 0.59% | 518,441 | -12% | 0% | $4,126,790 |
| Amova Asset Management Americas, Inc. | 0.59% | 518,441 | -12% | 0.05% | $4,126,790 |
| STATE OF MICHIGAN RETIREMENT SYSTEM | 0.56% | 493,798 | 0% | 0.02% | $3,930,632 |
| Portolan Capital Management, LLC | 0.43% | 379,197 | 0.16% | $3,018,408 | |
| FIRST MANHATTAN CO. LLC. | 0.42% | 373,822 | 0.01% | $2,975,623 | |
| NORTHERN TRUST CORP | 0.4% | 354,918 | -9.9% | 0% | $2,825,147 |
| GOLDMAN SACHS GROUP INC | 0.39% | 342,475 | -40% | 0% | $2,726,101 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 80,989,827 | $644,683,644 | +$129,639,537 | $7.96 | 123 |
| 2025 Q3 | 64,702,482 | $421,838,154 | +$27,589,778 | $6.52 | 107 |
| 2025 Q2 | 60,456,657 | $396,611,525 | +$44,202,043 | $6.56 | 105 |
| 2025 Q1 | 54,828,320 | $192,441,316 | +$10,090,223 | $3.51 | 102 |
| 2024 Q4 | 51,601,342 | $298,243,551 | -$3,572,926 | $5.78 | 107 |
| 2024 Q3 | 29,319,270 | $161,516,207 | +$43,033,654 | $5.38 | 83 |
| 2024 Q2 | 21,956,574 | $25,689,907 | -$438,121 | $1.17 | 69 |
| 2024 Q1 | 22,271,019 | $33,182,519 | +$217,168 | $1.49 | 70 |
| 2023 Q4 | 21,963,535 | $46,098,090 | -$4,605,029 | $2.10 | 68 |
| 2023 Q3 | 24,787,157 | $29,989,246 | -$2,223,907 | $1.21 | 63 |
| 2023 Q2 | 26,077,892 | $48,999,684 | -$2,366,338 | $1.88 | 64 |
| 2023 Q1 | 27,192,343 | $74,996,760 | +$205,499 | $2.76 | 62 |
| 2022 Q4 | 27,801,895 | $55,045,447 | -$1,904,858 | $1.98 | 78 |
| 2022 Q3 | 28,367,717 | $83,900,229 | -$5,226,601 | $2.97 | 77 |
| 2022 Q2 | 29,874,257 | $105,564,934 | -$15,549,124 | $3.45 | 95 |
| 2022 Q1 | 32,474,275 | $265,328,914 | -$398,164 | $8.19 | 120 |
| 2021 Q4 | 32,151,998 | $456,199,133 | +$2,045,734 | $14.27 | 105 |
| 2021 Q3 | 31,406,739 | $604,224,567 | -$14,422,392 | $19.24 | 116 |
| 2021 Q2 | 31,940,492 | $807,886,761 | +$23,454,157 | $25.30 | 132 |
| 2021 Q1 | 30,722,882 | $755,704,555 | +$60,986,103 | $24.61 | 130 |
| 2020 Q4 | 26,591,341 | $973,697,818 | +$110,231,063 | $36.61 | 128 |
| 2020 Q3 | 25,391,300 | $552,000,648 | +$128,507,444 | $21.67 | 90 |
| 2020 Q2 | 18,853,701 | $244,721,982 | +$7,255,056 | $12.97 | 77 |
| 2020 Q1 | 19,072,243 | $153,524,384 | +$10,223,267 | $8.07 | 65 |
| 2019 Q4 | 17,416,312 | $189,722,226 | +$10,096,228 | $10.90 | 76 |
| 2019 Q3 | 15,759,296 | $231,238,606 | -$27,642,247 | $14.68 | 67 |
| 2019 Q2 | 14,833,656 | $403,226,244 | +$403,226,232 | $27.15 | 67 |