PALVELLA THERAPEUTICS, INC. - Common Stock, $0.001 par value per share (PVLA) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2024 to Q4 2025

Type / Class
Equity / Common Stock, $0.001 par value per share
Symbol
PVLA on Nasdaq
Shares outstanding
11,772,667
Price per share
$100.49
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
4,609,067
Total reported value
$482,433,725
% of total 13F portfolios
0%
Share change
+745,007
Value change
+$93,113,354
Number of holders
94
Price from insider filings
$100.49
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of PALVELLA THERAPEUTICS, INC. - Common Stock, $0.001 par value per share (PVLA) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Kaupinen Wes 15% $38,555,729 1,644,869 Kaupinen Wes 13 Dec 2024
BIOTECHNOLOGY VALUE FUND L P 10% $74,049,052 1,181,194 BVF PARTNERS L P/IL 30 Sep 2025
SUVRETTA CAPITAL MANAGEMENT, LLC 7.4% -13% $51,556,256 +$6,766,571 822,400 +15% SUVRETTA CAPITAL MANAGEMENT, LLC 30 Sep 2025
Frazier Life Sciences Public Fund, L.P. 6% +22% $70,982,116 +$16,164,419 706,360 +29% Frazier Life Sciences Public Fund, L.P. 31 Dec 2025
Samsara BioCapital, L.P. 3.1% -50% $8,989,600 -$8,989,600 339,743 -50% Samsara BioCapital, L.P. 30 Jun 2025
Dellora Investments LP 1.3% $3,306,892 141,079 Dellora Investments LP 13 Dec 2024

As of 31 Dec 2025, 94 institutional investors reported holding 4,609,067 shares of PALVELLA THERAPEUTICS, INC. - Common Stock, $0.001 par value per share (PVLA). This represents 39% of the company’s total 11,772,667 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of PALVELLA THERAPEUTICS, INC. - Common Stock, $0.001 par value per share (PVLA) together control 37% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Frazier Life Sciences Management, L.P. 6.1% 722,400 0% 2% $75,613,608
VANGUARD GROUP INC 4.8% 560,616 +13% 0% $58,679,676
BlackRock, Inc. 4.7% 559,065 +15% 0% $58,517,334
STATE STREET CORP 3.6% 420,462 +206% 0% $44,009,758
JENNISON ASSOCIATES LLC 3.3% 387,483 +262% 0.02% $40,557,846
FEDERATED HERMES, INC. 3.1% 368,038 +8.6% 0.06% $38,522,537
MORGAN STANLEY 1.9% 220,662 +59% 0% $23,096,692
GEODE CAPITAL MANAGEMENT, LLC 1.5% 178,992 +6.5% 0% $18,739,109
EVENTIDE ASSET MANAGEMENT, LLC 0.86% 101,748 0.17% $10,649,963
GOLDMAN SACHS GROUP INC 0.84% 98,935 -58% 0% $10,355,526
Clio Asset Management LLC 0.78% 91,642 +0% 7.4% $9,592,168
NEXTBio Capital Management LP 0.7% 82,686 0% 5.1% $8,654,744
Siren, L.L.C. 0.64% 75,000 0.23% $7,850,250
AWM Investment Company, Inc. 0.59% 69,416 0% 0.7% $7,265,773
Clearbridge Investments, LLC 0.51% 60,628 0.01% $6,345,881
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.41% 47,681 0% $4,990,771
NEUBERGER BERMAN GROUP LLC 0.38% 44,901 0% $4,699,787
Lisanti Capital Growth, LLC 0.35% 41,470 1% $4,340,665
Blue Owl Capital Holdings LP 0.34% 40,259 -58% 0.32% $4,213,910
UBS Group AG 0.31% 36,505 +79% 0% $3,820,979
ROYCE & ASSOCIATES LP 0.25% 30,010 -39% 0.03% $3,141,147
BARCLAYS PLC 0.21% 25,136 +157% 0% $2,630,986
RENAISSANCE TECHNOLOGIES LLC 0.19% 22,530 -75% 0% $2,358,215
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.18% 21,633 +3% 0% $2,264,326
Nuveen, LLC 0.17% 19,576 +54% 0% $2,049,020

Institutional Holders of PALVELLA THERAPEUTICS, INC. - Common Stock, $0.001 par value per share (PVLA) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 4,609,067 $482,433,725 +$93,113,354 $104.67 94
2025 Q3 8,525,488 $534,466,075 +$183,107,977 $62.69 100
2025 Q2 5,909,706 $133,205,244 +$16,635,084 $22.54 64
2025 Q1 5,123,397 $143,404,590 +$33,701,617 $27.99 40
2024 Q4 4,033,052 $48,417,227 +$48,417,227 $12.00 32