PTC THERAPEUTICS, INC. - Common Stock (PTCT) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2014 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
PTCT on Nasdaq
Shares outstanding
80,855,533
Price per share
$76.43
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
91,733,987
Total reported value
$6,968,391,159
% of total 13F portfolios
0%
Share change
+8,475,521
Value change
+$673,643,502
Number of holders
342
Price from insider filings
$76.43
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of PTC THERAPEUTICS, INC. - Common Stock (PTCT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BlackRock, Inc. 15% +85% $892,256,965 +$421,991,884 11,904,696 +90% BlackRock, Inc. 30 Nov 2025
VANGUARD GROUP INC 10% $508,695,869 8,288,999 The Vanguard Group 30 Sep 2025
ARMISTICE CAPITAL, LLC 6.9% -18% $269,133,425 -$46,705,135 5,434,843 -15% Armistice Capital, LLC 31 Mar 2025
JANUS HENDERSON GROUP PLC 6% $376,123,770 4,851,332 JANUS HENDERSON GROUP PLC 31 Dec 2025
STATE STREET CORP 5.2% $326,100,949 4,206,126 STATE STREET CORPORATION 31 Dec 2025
TORONTO DOMINION BANK 5.2% $320,835,809 4,138,215 The Toronto-Dominion Bank 31 Dec 2025
WELLINGTON MANAGEMENT GROUP LLP 4.8% -23% $299,837,971 -$71,307,675 3,867,380 -19% Wellington Management Group LLP 31 Dec 2025
Camber Capital Management LP 4.2% $158,464,000 3,200,000 Camber Capital Management LP 31 Dec 2024

As of 31 Dec 2025, 342 institutional investors reported holding 91,733,987 shares of PTC THERAPEUTICS, INC. - Common Stock (PTCT). This represents 113% of the company’s total 80,855,533 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of PTC THERAPEUTICS, INC. - Common Stock (PTCT) together control 87% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 16% 12,779,065 +79% 0.02% $970,697,777
VANGUARD GROUP INC 11% 8,803,203 +6.2% 0.01% $668,691,300
RTW INVESTMENTS, LP 9.6% 7,746,415 0% 5.9% $588,417,683
JANUS HENDERSON GROUP PLC 6% 4,851,332 +29% 0.17% $368,586,978
STATE STREET CORP 5.2% 4,206,126 +34% 0.01% $319,497,331
TORONTO DOMINION BANK 5.1% 4,138,215 +27% 0.55% $314,338,811
WELLINGTON MANAGEMENT GROUP LLP 4.8% 3,867,380 -21% 0.05% $293,766,184
ARMISTICE CAPITAL, LLC 3.5% 2,801,869 -15% 5.2% $212,829,969
GEODE CAPITAL MANAGEMENT, LLC 2.5% 2,016,062 +3.3% 0.01% $153,164,342
D. E. Shaw & Co., Inc. 2.2% 1,744,991 -20% 0.1% $132,549,516
FMR LLC 2.1% 1,681,216 +4.3% 0.01% $127,705,195
Jefferies Financial Group Inc. 2.1% 1,658,481 +4.7% 1% $125,978,217
TANG CAPITAL MANAGEMENT LLC 1.9% 1,500,000 0% 5.6% $113,940,000
BANK OF AMERICA CORP /DE/ 1.8% 1,431,557 -5.6% 0.01% $108,741,069
FRANKLIN RESOURCES INC 1.6% 1,286,685 +11% 0.02% $97,736,593
CITADEL ADVISORS LLC 1.4% 1,154,455 -33% 0.06% $87,692,401
Driehaus Capital Management LLC 1.4% 1,136,188 +0.39% 0.59% $86,304,840
Point72 Asset Management, L.P. 1.4% 1,128,551 -7.5% 0.13% $85,724,734
GOLDMAN SACHS GROUP INC 1.3% 1,023,091 +17% 0.01% $77,713,992
Hood River Capital Management LLC 1.2% 1,003,075 +0.73% 0.84% $76,193,577
Pictet Asset Management Holding SA 1.2% 978,957 -30% 0.07% $74,789,278
UBS Group AG 1.2% 964,658 +113% 0.01% $73,275,422
MORGAN STANLEY 1.1% 905,192 +116% 0% $68,758,446
Palo Alto Investors LP 1.1% 903,916 +4.8% 9.6% $68,661,459
SG Americas Securities, LLC 1.1% 894,461 +588% 0.09% $67,943,000

Institutional Holders of PTC THERAPEUTICS, INC. - Common Stock (PTCT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 91,733,987 $6,968,391,159 +$673,643,502 $75.96 342
2025 Q3 82,687,563 $5,074,316,541 +$181,658,820 $61.37 291
2025 Q2 79,911,059 $3,903,121,530 +$46,553,598 $48.84 281
2025 Q1 78,779,105 $4,025,030,193 +$67,568,904 $50.96 260
2024 Q4 77,719,633 $3,508,291,455 -$16,690,343 $45.14 237
2024 Q3 78,808,939 $2,925,502,301 -$38,880,960 $37.10 199
2024 Q2 79,829,985 $2,441,610,603 -$156,636,791 $30.58 196
2024 Q1 85,061,593 $2,474,579,740 +$22,339,643 $29.09 179
2023 Q4 84,601,340 $2,331,624,240 +$83,990,908 $27.56 169
2023 Q3 81,614,706 $1,828,981,040 -$51,055,249 $22.41 175
2023 Q2 81,025,132 $3,295,908,701 +$98,098,293 $40.67 201
2023 Q1 78,433,463 $3,798,260,033 +$90,684,481 $48.44 198
2022 Q4 76,981,862 $2,938,237,687 +$13,606,355 $38.17 196
2022 Q3 76,313,271 $3,830,944,634 +$86,495,993 $50.20 199
2022 Q2 74,083,474 $2,967,960,851 +$15,896,836 $40.06 171
2022 Q1 73,730,204 $2,750,879,876 -$34,162,193 $37.31 170
2021 Q4 75,095,879 $2,991,389,896 +$33,191,074 $39.83 166
2021 Q3 74,270,018 $2,763,598,375 +$31,311,987 $37.21 174
2021 Q2 73,830,496 $3,120,577,918 +$3,824,478 $42.27 174
2021 Q1 73,197,638 $3,466,689,095 +$45,849,603 $47.35 196
2020 Q4 72,827,805 $4,447,644,286 +$100,239,157 $61.03 205
2020 Q3 71,012,920 $3,320,619,406 +$114,326,210 $46.75 189
2020 Q2 68,359,820 $3,451,278,985 +$259,126,213 $50.74 198
2020 Q1 64,213,019 $2,865,901,646 +$125,294,621 $44.61 197
2019 Q4 61,124,372 $2,935,863,409 +$23,562,040 $48.03 203
2019 Q3 61,919,993 $2,094,320,996 +$114,605,453 $33.82 181
2019 Q2 58,378,537 $2,626,676,199 +$33,782,408 $45.00 173
2019 Q1 58,617,454 $2,206,343,369 +$373,569,818 $37.64 169
2018 Q4 48,764,141 $1,672,916,979 +$32,659,099 $34.32 160
2018 Q3 46,800,681 $2,199,661,172 +$196,122,715 $47.00 176
2018 Q2 42,887,283 $1,446,483,123 +$13,935,444 $33.73 164
2018 Q1 42,685,949 $1,154,889,575 +$143,231,958 $27.06 146
2017 Q4 38,109,969 $635,678,067 +$18,883,443 $16.68 119
2017 Q3 35,744,834 $715,228,449 +$44,754,005 $20.01 126
2017 Q2 33,526,261 $614,523,105 +$64,351,306 $18.33 111
2017 Q1 31,527,213 $310,226,812 +$57,103,339 $9.84 111
2016 Q4 28,676,672 $312,896,583 -$24,470,762 $10.91 117
2016 Q3 29,224,066 $409,245,732 +$31,590,430 $14.01 110
2016 Q2 28,567,042 $202,093,852 -$12,310,362 $7.02 113
2016 Q1 29,052,236 $187,275,624 -$209,529,061 $6.44 112
2015 Q4 36,309,263 $1,175,380,829 +$117,821,671 $32.40 141
2015 Q3 33,048,603 $881,940,071 -$17,562,428 $26.70 154
2015 Q2 32,610,815 $1,570,066,541 +$38,237,714 $48.13 152
2015 Q1 31,473,162 $1,915,082,191 +$210,644,324 $60.85 157
2014 Q4 28,362,106 $1,468,602,926 +$198,969,370 $51.77 131
2014 Q3 24,376,802 $1,072,967,175 +$75,631,280 $44.01 99
2014 Q2 22,967,349 $600,370,273 +$12,312 $26.14 83
2014 Q1 22,954,586 $600,024,825 +$219,416,366 $26.14 63