| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11% | +6% | $388,340,181 | +$31,912,348 | 5,445,039 | +9% | JANUS HENDERSON GROUP PLC | 28 Nov 2025 |
| Frazier Life Sciences IX, L.P. | 7.4% | 0% | $273,828,978 | 3,735,220 | 0% | James N. Topper | 01 Nov 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC | 5.4% | $107,692,609 | 2,606,938 | Eventide Asset Management, LLC | 31 Dec 2024 | |||
| BIOTECHNOLOGY VALUE FUND L P | 3% | $109,619,710 | 1,495,290 | BVF PARTNERS L P/IL | 30 Sep 2025 |
As of 30 Sep 2025, 268 institutional investors reported holding 57,251,920 shares of Mirum Pharmaceuticals, Inc. - Common Stock (MIRM). This represents 111% of the company’s total 51,368,292 outstanding shares.
The largest institutional shareholders of Mirum Pharmaceuticals, Inc. - Common Stock (MIRM) together control 75% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 13% | 6,795,121 | 0% | 15% | $498,150,321 |
| JANUS HENDERSON GROUP PLC | 9.7% | 4,997,586 | -4.6% | 0.17% | $366,518,621 |
| BlackRock, Inc. | 7% | 3,602,434 | +0.71% | 0% | $264,094,437 |
| VANGUARD GROUP INC | 5% | 2,545,369 | -0.76% | 0% | $186,601,001 |
| EVENTIDE ASSET MANAGEMENT, LLC | 4.9% | 2,522,563 | -4.4% | 3% | $184,923,401 |
| BVF INC/IL | 2.9% | 1,495,290 | -46% | 4.4% | $109,619,710 |
| STATE STREET CORP | 2.6% | 1,346,904 | -2.1% | 0% | $98,741,532 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.5% | 1,283,288 | -9.5% | 0.01% | $94,079,000 |
| NOVO HOLDINGS A/S | 2.5% | 1,264,028 | -16% | 6% | $92,665,893 |
| TANG CAPITAL MANAGEMENT LLC | 2.4% | 1,236,027 | 0% | 3.5% | $90,613,139 |
| CITADEL ADVISORS LLC | 2% | 1,040,544 | -26% | 0.06% | $76,282,281 |
| GEODE CAPITAL MANAGEMENT, LLC | 2% | 1,010,022 | -1.9% | 0% | $74,056,868 |
| Clearbridge Investments, LLC | 2% | 1,003,803 | -2.3% | 0.06% | $73,588,785 |
| D. E. Shaw & Co., Inc. | 1.8% | 923,509 | +66% | 0.05% | $67,702,445 |
| Polar Capital Holdings Plc | 1.6% | 820,552 | -16% | 0.29% | $60,154,667 |
| WELLINGTON MANAGEMENT GROUP LLP | 1.5% | 790,689 | +567% | 0.01% | $57,965,410 |
| Point72 Asset Management, L.P. | 1.5% | 790,675 | +205% | 0.13% | $57,964,420 |
| Rock Springs Capital Management LP | 1.5% | 761,126 | -7% | 3.3% | $55,798,147 |
| MORGAN STANLEY | 1.3% | 670,149 | +18% | 0% | $49,128,631 |
| LORD, ABBETT & CO. LLC | 1.3% | 661,940 | -14% | 0.14% | $48,527,000 |
| FMR LLC | 1.2% | 640,218 | +977% | 0% | $46,934,414 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1.2% | 612,318 | +709% | 0.03% | $44,889,033 |
| Nuveen, LLC | 1.2% | 601,670 | +1.9% | 0.01% | $44,108,428 |
| FRANKLIN RESOURCES INC | 1.2% | 601,137 | +1.3% | 0.01% | $44,069,353 |
| BNP PARIBAS FINANCIAL MARKETS | 1.2% | 601,073 | 0% | 0.03% | $44,064,662 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 196,253 | $15,479,486 | -$222,499 | $78.99 | 19 |
| 2025 Q3 | 57,251,920 | $4,197,137,283 | +$132,882,990 | $73.31 | 268 |
| 2025 Q2 | 55,393,029 | $2,819,019,204 | +$70,434,976 | $50.89 | 211 |
| 2025 Q1 | 54,142,705 | $2,443,759,313 | +$49,081,267 | $45.05 | 213 |
| 2024 Q4 | 52,986,109 | $2,190,964,431 | -$26,045,809 | $41.35 | 204 |
| 2024 Q3 | 53,301,609 | $2,079,251,226 | -$2,890,149 | $39.00 | 176 |
| 2024 Q2 | 53,362,791 | $1,824,471,702 | +$17,964,526 | $34.19 | 157 |
| 2024 Q1 | 53,243,448 | $1,337,601,222 | +$70,337,692 | $25.12 | 167 |
| 2023 Q4 | 50,259,606 | $1,483,847,413 | +$1,676,068 | $29.52 | 184 |
| 2023 Q3 | 48,930,333 | $1,545,592,030 | +$398,674,334 | $31.60 | 156 |
| 2023 Q2 | 36,937,639 | $955,518,729 | +$63,103,719 | $25.87 | 143 |
| 2023 Q1 | 34,669,406 | $832,753,531 | +$33,992,984 | $24.02 | 114 |
| 2022 Q4 | 33,331,988 | $650,146,380 | -$12,725,497 | $19.50 | 101 |
| 2022 Q3 | 33,748,714 | $709,089,633 | +$93,197,315 | $21.01 | 107 |
| 2022 Q2 | 29,289,263 | $568,434,366 | +$47,575,699 | $19.46 | 104 |
| 2022 Q1 | 26,813,353 | $590,437,915 | -$6,195,298 | $22.02 | 99 |
| 2021 Q4 | 22,891,220 | $365,087,000 | +$18,990,411 | $15.95 | 81 |
| 2021 Q3 | 21,414,209 | $426,514,254 | +$2,080,056 | $19.92 | 69 |
| 2021 Q2 | 21,482,092 | $371,413,185 | +$642,669 | $17.29 | 66 |
| 2021 Q1 | 21,451,984 | $425,174,000 | -$8,433,468 | $19.82 | 60 |
| 2020 Q4 | 22,010,623 | $384,380,000 | +$52,268,047 | $17.46 | 71 |
| 2020 Q3 | 18,743,135 | $361,180,000 | -$1,290,295 | $19.27 | 50 |
| 2020 Q2 | 18,808,446 | $366,015,000 | +$8,936,163 | $19.46 | 57 |
| 2020 Q1 | 18,603,225 | $260,445,000 | +$32,083,278 | $14.00 | 43 |
| 2019 Q4 | 16,248,910 | $398,421,000 | +$12,819,124 | $24.52 | 39 |
| 2019 Q3 | 16,487,274 | $165,856,000 | +$165,755,000 | $10.06 | 38 |