Security Snapshot

Mineralys Therapeutics, Inc. - COMMON STOCK (MLYS) Institutional Ownership

CUSIP: 603170101

13F Institutional Holders and Ownership History from Q1 2023 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

223

Shares (Excl. Options)

99,595,011

Price

$26.98

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
+9,333,306
Value change
+$251,180,033
Number of holders
223
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
87,484,107
SEC-reported price per share
$26.71
Insider filing price
$26.71
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • MLYS - Mineralys Therapeutics, Inc. - COMMON STOCK is tracked under CUSIP 603170101.
  • 223 institutions reported positions in Q2 2026.
  • 7 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 213 to 223 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $2,455,035,905 to $2,687,207,911.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 223 institutions filings for Q2 2026.

Open SEC evidence

Security key

603170101

Latest holder period

Q2 2026

13F holders

223

13D/G owners

7

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
7
Security
MLYS
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Catalys Pacific Fund, LP 10% -24% $267,051,367 -$32,576,328 8,002,738 -11% Catalys Pacific Fund, LP 31 Dec 2025
RA CAPITAL MANAGEMENT, L.P. 9.9% 0% $104,939,988 +$20,308,933 7,796,433 +24% RA Capital Management, L.P. 04 Sep 2025
Samsara BioCapital, L.P. 8.2% -10% $85,419,771 +$8,209,106 6,346,194 +11% Srinivas Akkaraju 04 Sep 2025
FMR LLC 5.1% -20% $123,544,181 -$15,390,656 4,461,689 -11% FMR LLC 30 Jun 2026
BlackRock, Inc. 5.2% $149,286,258 4,113,657 BlackRock, Inc. 31 Dec 2025
Andera Partners 4.2% $39,747,075 2,765,976 Andera Partners 30 Jun 2025
ADAMS STREET PARTNERS LLC 2.3% $15,320,183 1,129,807 Adams Street Partners, LLC 31 Dec 2024

As of 30 Jun 2026, 223 institutional investors reported holding 99,595,011 shares of Mineralys Therapeutics, Inc. - COMMON STOCK (MLYS). This represents 114% of the company’s total 87,484,107 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
81%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Catalys Pacific, LLC 9% 7,903,838 0% 93% $213,245,549
RA CAPITAL MANAGEMENT, L.P. 8.8% 7,692,750 0% 1.8% $207,550,395
BlackRock, Inc. 6.7% 5,887,038 +31% 0% $158,832,288
SAMSARA BIOCAPITAL, LLC 6.7% 5,871,018 0% 13% $158,400,066
FMR LLC 5.2% 4,511,689 -7.2% 0.01% $121,725,382
STATE STREET CORP 4.7% 4,141,636 +41% 0% $111,741,339
DEERFIELD MANAGEMENT COMPANY, L.P. 4.5% 3,958,000 1.1% $106,786,840
VANGUARD CAPITAL MANAGEMENT LLC 3.2% 2,756,770 +12% 0% $74,377,655
Laurion Capital Management LP 2.9% 2,506,152 +12% 4.9% $67,615,981
PRICE T ROWE ASSOCIATES INC /MD/ 2.6% 2,262,476 +68% 0.01% $61,042,000
ORBIMED ADVISORS LLC 2.4% 2,110,300 +2.8% 1.1% $56,935,894
Capital World Investors 2.3% 1,997,607 +402% 0.01% $53,895,437
ARMISTICE CAPITAL, LLC 2% 1,736,000 +48% 1.3% $46,837,280
Troluce Capital Advisors LLC 2% 1,728,753 +164% 17% $46,641,756
FRANKLIN RESOURCES INC 1.9% 1,635,520 -8.4% 0.01% $44,126,329
ANDERA PARTNERS 1.8% 1,591,917 0% 21% $42,949,921
GEODE CAPITAL MANAGEMENT, LLC 1.8% 1,584,326 +22% 0% $42,753,193
SR One Capital Management, LP 1.8% 1,563,966 0% 4.1% $42,195,803
BANK OF AMERICA CORP /DE/ 1.7% 1,505,547 +37% 0% $40,619,658
SPHERA FUNDS MANAGEMENT LTD. 1.7% 1,469,971 +9.7% 5.7% $39,659,818
GOLDMAN SACHS GROUP INC 1.7% 1,458,676 +86% 0% $39,355,079
Pictet Asset Management Holding SA 1.6% 1,430,649 +38% 0.04% $38,598,910
Polar Capital Holdings Plc 1.6% 1,420,854 -5.3% 0.11% $38,334,641
MILLENNIUM MANAGEMENT LLC 1.4% 1,221,758 +133% 0.02% $32,963,031
Ghisallo Capital Management LLC 1.3% 1,125,000 0.6% $30,352,500

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
14
Latest
Q2 2026
Rows shown
1-14 of 14
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 99,595,011 $2,687,207,911 +$251,180,033 $26.98 223
2026 Q1 90,325,196 $2,455,035,905 -$6,333,390 $27.09 213
2025 Q4 88,390,661 $3,207,524,350 +$270,032,812 $36.29 223
2025 Q3 79,306,949 $3,007,317,130 +$505,416,563 $37.92 191
2025 Q2 65,687,280 $888,767,559 +$52,640,107 $13.53 164
2025 Q1 61,178,854 $971,385,613 +$245,430,113 $15.88 148
2024 Q4 46,486,259 $572,248,542 +$24,847,746 $12.31 108
2024 Q3 44,382,325 $540,052,185 +$2,379,010 $12.11 105
2024 Q2 44,151,028 $516,569,023 +$24,151,320 $11.70 93
2024 Q1 41,871,642 $540,562,541 +$93,970,804 $12.91 91
2023 Q4 34,713,391 $298,534,855 -$5,432,193 $8.60 87
2023 Q3 26,512,068 $252,135,025 -$9,247,223 $9.51 77
2023 Q2 25,186,898 $429,224,695 +$10,759,767 $17.05 68
2023 Q1 24,614,198 $385,431,208 +$385,431,208 $15.66 66
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