13F reference period
Q2 2026
CUSIP: 578784100
13F reference period
Q2 2026
Institutions Reporting
160
Shares (Excl. Options)
Price
$29.84
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 160 institutions filings for Q2 2026.
Security key
578784100
13F reference period
Q2 2026
13F holders
160
13D/G owners
9
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 578784100:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Third Rock Ventures IV, L.P. | 9.3% | -33% | $179,808,372 | -$64,304,000 | 4,473,958 | -26% | Third Rock Ventures IV, L.P. | 31 Dec 2025 |
| Frazier Life Sciences Public Fund, L.P. | 9% | +16% | $174,515,671 | +$39,762,017 | 4,342,266 | +30% | Frazier Life Sciences Public Fund, L.P. | 31 Dec 2025 |
| ARCH Venture Fund X, L.P. | 9.4% | $36,215,266 | 4,120,053 | ARCH Venture Fund X, L.P. | 31 Mar 2025 | |||
| Deep Track Capital, LP | 9% | +30% | $59,431,096 | +$13,927,661 | 3,948,910 | +31% | Deep Track Capital, LP | 30 Jun 2025 |
| BlackRock, Inc. | 5.4% | $88,865,731 | 2,978,114 | BlackRock, Inc. | 30 Jun 2026 | |||
| JANUS HENDERSON GROUP PLC | 5.8% | -21% | $78,390,380 | -$9,531,082 | 2,858,876 | -11% | JANUS HENDERSON GROUP PLC | 31 Mar 2026 |
| Matrix Capital Management Company, LP | 3.5% | -37% | $42,880,026 | -$21,586,725 | 1,653,684 | -33% | Matrix Capital Management Company, LP | 30 Sep 2025 |
| GV 2019, L.P. | 2.9% | -52% | $57,528,994 | -$42,419,680 | 1,388,583 | -42% | Alphabet Holdings LLC | 31 Dec 2025 |
| Foresite Capital Fund IV, L.P. | 1.4% | -70% | $15,790,022 | -$47,922,789 | 608,948 | -75% | James Tananbaum | 30 Sep 2025 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 9.1% | 5,032,915 | +10% | 3.3% | $150,182,184 |
| TRV GP IV, LLC | 8.1% | 4,473,958 | 0% | 53% | $133,502,907 |
| ARCH Venture Management, LLC | 7.5% | 4,120,053 | 0% | 11% | $122,983,582 |
| Deep Track Capital, LP | 6.8% | 3,732,569 | +7.3% | 1.6% | $111,379,859 |
| BlackRock, Inc. | 6.4% | 3,502,841 | +36% | 0% | $104,524,775 |
| Jupiter Topco LLC | 6.2% | 3,408,045 | 0% | 0.04% | $101,764,224 |
| T. Rowe Price Investment Management, Inc. | 4.7% | 2,603,682 | 0.05% | $77,694,000 | |
| Logos Global Management LP | 3.5% | 1,935,000 | +57% | 2.5% | $57,740,400 |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.2% | 1,778,222 | +24% | 0% | $53,062,144 |
| a16z Capital Management, L.L.C. | 3.1% | 1,702,225 | 0% | 0.36% | $50,794,394 |
| Venrock Adviser, LLC | 2.9% | 1,602,034 | 0% | 1.4% | $47,804,695 |
| Alphabet Inc. | 2.5% | 1,388,583 | 0% | 0.04% | $41,435,317 |
| BRAIDWELL LP | 2.1% | 1,140,040 | 1.3% | $34,018,794 | |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 2% | 1,107,814 | +197% | 0.19% | $33,057,170 |
| FMR LLC | 1.9% | 1,056,959 | +22% | 0% | $31,539,649 |
| General Catalyst Group Management, LLC | 1.9% | 1,035,910 | 0% | 16% | $30,911,554 |
| STATE STREET CORP | 1.8% | 997,533 | +57% | 0% | $29,766,385 |
| JPMORGAN CHASE & CO | 1.7% | 964,011 | +1549% | 0% | $27,995,382 |
| Driehaus Capital Management LLC | 1.7% | 954,886 | +50% | 0.17% | $28,493,798 |
| TRV GP V, LLC | 1.7% | 950,800 | 0% | 5.7% | $28,371,872 |
| MARSHALL WACE, LLP | 1.7% | 914,572 | +194% | 0.02% | $27,290,827 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 858,054 | +43% | 0% | $25,608,436 |
| CITADEL ADVISORS LLC | 1.5% | 852,676 | +9.9% | 0.01% | $25,443,852 |
| Casdin Capital, LLC | 1.5% | 843,857 | +11% | 1.3% | $25,180,693 |
| ArrowMark Colorado Holdings LLC | 1.4% | 767,383 | 0% | 0.95% | $22,898,709 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 133,791 | $3,634,243 | +$2,438,750 | $27.18 | 15 |
| 2026 Q2 | 58,534,404 | $1,745,780,907 | +$185,206,340 | $29.84 | 160 |
| 2026 Q1 | 51,677,471 | $1,543,189,088 | +$68,960,987 | $29.85 | 164 |
| 2025 Q4 | 48,370,369 | $2,003,833,642 | +$199,439,391 | $41.43 | 144 |
| 2025 Q3 | 42,970,633 | $1,114,223,528 | +$108,250,260 | $25.93 | 93 |
| 2025 Q2 | 38,836,437 | $476,719,891 | -$14,337,293 | $12.27 | 74 |
| 2025 Q1 | 40,038,674 | $441,393,439 | +$441,263,796 | $11.01 | 68 |