Security Snapshot

Maze Therapeutics, Inc. - Common Stock (MAZE) Institutional Ownership

CUSIP: 578784100

13F Institutional Holders and Ownership History from Q1 2025 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

164

Shares (Excl. Options)

51,677,471

Price

$29.85

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Type / Class
Equity / Common Stock
Symbol
MAZE on Nasdaq
Shares outstanding
49,290,966
Price per share
$26.47
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
51,677,471
Total reported value
$1,543,189,088
% of total 13F portfolios
0%
Share change
+3,214,670
Value change
+$68,963,225
Number of holders
164
Price from insider filings
$26.47
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • MAZE - Maze Therapeutics, Inc. - Common Stock is tracked under CUSIP 578784100.
  • 164 institutions reported positions in Q1 2026.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 144 to 164 between Q4 2025 and Q1 2026.
  • Reported value moved from $2,003,833,642 to $1,543,189,088.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 164 institutions filings for Q1 2026.

Open SEC Evidence

Security key

578784100

Latest holder period

Q1 2026

13F holders

164

13D/G owners

9

CIK / CUSIP context first

Significant Owners of Maze Therapeutics, Inc. - Common Stock (MAZE) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Third Rock Ventures IV, L.P. 9.3% -33% $179,808,372 -$64,304,000 4,473,958 -26% Third Rock Ventures IV, L.P. 31 Dec 2025
Frazier Life Sciences Public Fund, L.P. 9% +16% $174,515,671 +$39,762,017 4,342,266 +30% Frazier Life Sciences Public Fund, L.P. 31 Dec 2025
ARCH Venture Fund X, L.P. 9.4% $36,215,266 4,120,053 ARCH Venture Fund X, L.P. 31 Mar 2025
Deep Track Capital, LP 9% +30% $59,431,096 +$13,927,661 3,948,910 +31% Deep Track Capital, LP 30 Jun 2025
Paradigm Biocapital Advisors LP 6.1% $155,788,502 3,051,087 Paradigm BioCapital Advisors LP 25 Mar 2026
JANUS HENDERSON GROUP PLC 5.8% -21% $78,390,380 -$9,531,082 2,858,876 -11% JANUS HENDERSON GROUP PLC 31 Mar 2026
Matrix Capital Management Company, LP 3.5% -37% $42,880,026 -$21,586,725 1,653,684 -33% Matrix Capital Management Company, LP 30 Sep 2025
GV 2019, L.P. 2.9% -52% $57,528,994 -$42,419,680 1,388,583 -42% Alphabet Holdings LLC 31 Dec 2025
Foresite Capital Fund IV, L.P. 1.4% -70% $15,790,022 -$47,922,789 608,948 -75% James Tananbaum 30 Sep 2025

As of 31 Mar 2026, 164 institutional investors reported holding 51,677,471 shares of Maze Therapeutics, Inc. - Common Stock (MAZE). This represents 105% of the company’s total 49,290,966 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Maze Therapeutics, Inc. - Common Stock (MAZE) together control 86% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Frazier Life Sciences Management, L.P. 9.3% 4,567,274 0% 3.5% $136,333,129
TRV GP IV, LLC 9.1% 4,473,958 0% 50% $133,547,646
ARCH Venture Management, LLC 8.4% 4,120,053 0% 18% $122,983,582
Deep Track Capital, LP 7.1% 3,477,562 -18% 2.1% $103,805,226
JANUS HENDERSON GROUP PLC 5.8% 2,858,876 -9% 0.04% $85,280,271
Paradigm Biocapital Advisors LP 5.6% 2,744,399 1.7% $81,920,310
BlackRock, Inc. 5.2% 2,570,425 +12% 0% $76,727,187
a16z Capital Management, L.L.C. 3.5% 1,702,225 0% 3.9% $50,811,416
Venrock Adviser, LLC 3.3% 1,602,034 +3.5% 1.8% $47,820,715
VANGUARD CAPITAL MANAGEMENT LLC 2.9% 1,435,656 0% 0% $42,854,332
Alphabet Inc. 2.8% 1,388,583 0% 1% $41,449,203
Logos Global Management LP 2.5% 1,235,000 +30% 1.9% $36,864,750
ADAGE CAPITAL PARTNERS GP, L.L.C. 2.4% 1,178,000 0.05% $35,163,300
General Catalyst Group Management, LLC 2.1% 1,035,910 0% 17% $30,921,914
TRV GP V, LLC 1.9% 950,800 0% 7.1% $28,381,380
FMR LLC 1.8% 864,214 +19% 0% $25,796,788
CITADEL ADVISORS LLC 1.6% 775,714 +73% 0.02% $23,155,063
ArrowMark Colorado Holdings LLC 1.6% 767,383 0% 0.61% $22,906,383
Casdin Capital, LLC 1.5% 758,857 0% 1.7% $22,651,881
Cormorant Asset Management, LP 1.5% 750,000 1.1% $22,387,500
Woodline Partners LP 1.3% 650,229 -37% 0.07% $19,409,336
STATE STREET CORP 1.3% 636,722 +19% 0% $19,006,152
Driehaus Capital Management LLC 1.3% 636,162 +68% 0.14% $18,989,436
Caligan Partners LP 1.2% 614,962 +12% 1.3% $18,356,616
GEODE CAPITAL MANAGEMENT, LLC 1.2% 599,967 +14% 0% $17,912,855

Institutional Holders of Maze Therapeutics, Inc. - Common Stock (MAZE) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 51,677,471 $1,543,189,088 +$68,963,225 $29.85 164
2025 Q4 48,370,369 $2,003,833,642 +$199,439,391 $41.43 144
2025 Q3 42,970,633 $1,114,223,528 +$108,250,260 $25.93 93
2025 Q2 38,836,437 $476,719,891 -$14,337,293 $12.27 74
2025 Q1 40,038,674 $441,393,439 +$441,263,796 $11.01 68
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