Security key
55287L101
- Type / Class
- Equity / COMMON STOCK
- Shares outstanding
- 47,365,871
- Total 13F shares
- 48,428,720
- Share change
- -32,951
- Total reported value
- $1,527,258,385
- Put/Call ratio
- 365%
- Price per share
- $31.54
- Number of holders
- 138
- Value change
- +$34,720,034
- Number of buys
- 91
- Number of sells
- 50
Report period
Q4 2025
Institutions
138
Top holders
10
MBX full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
MBX Biosciences, Inc. SEC filings
MBX Biosciences, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 55287L101
Recent filing periods:
Top shareholders of MBX - MBX Biosciences, Inc. - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Public Fund, L.P. |
13D/G
|
Patrick J. Heron |
12%
|
5,224,095
|
$72,562,680 | +$9,264,602 | 26 Sep 2025 | |
| New Enterprise Associates 17, L.P. |
13D/G
3/4/5
|
Edward T. Mathers · 10%+ Owner |
8.1%
|
3,619,474
|
$63,340,795 | $0 | 06 Nov 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
13F
|
Company |
7.5%
|
3,349,961
|
$109,041,231 | -$47,958,356 | 31 Dec 2025 | |
| Deep Track Capital, LP |
13F
13D/G
|
Company |
6.6%
from 13D/G
|
3,150,000
|
$55,125,000 | — | 30 Sep 2025 | |
| Norwest Venture Partners XVI, LP |
13D/G
|
Tiba Aynechi |
4.8%
|
2,140,989
|
$29,738,337 | $0 | 26 Sep 2025 | |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. |
13D/G
3/4/5
|
10%+ Owner |
4.5%
|
2,017,394
|
$35,304,395 | $0 | 30 Sep 2025 | |
| P. Kent Hawryluk |
13D/G
|
— |
4.3%
|
1,995,759
|
$34,925,782 | $0 | 30 Sep 2025 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
14%
|
6,652,013
|
$116,410,228 | — | 30 Sep 2025 | |
| ORBIMED ADVISORS LLC |
13F
3/4/5
|
Company · Director, 10%+ Owner |
8.5%
|
4,002,887
|
$70,050,523 | — | 30 Sep 2025 | |
| NEA Management Company, LLC |
13F
|
Company |
7.6%
|
3,614,486
|
$63,253,505 | — | 30 Sep 2025 | |
| NVP Associates, LLC |
13F
|
Company |
4.5%
|
2,136,335
|
$37,385,863 | — | 30 Sep 2025 | |
| EcoR1 Capital, LLC |
13F
|
Company |
4.5%
|
2,123,604
|
$37,163,070 | — | 30 Sep 2025 | |
| Kynam Capital Management, LP |
13F
|
Company |
4.2%
|
2,000,000
|
$35,000,000 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
4.1%
|
1,957,461
|
$34,255,569 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
3.5%
|
1,677,362
|
$29,353,836 | — | 30 Sep 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
3.3%
|
1,539,639
|
$26,943,683 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
2.8%
|
1,307,288
|
$22,877,540 | — | 30 Sep 2025 | |
| Cormorant Asset Management, LP |
13F
|
Company |
2.6%
|
1,225,000
|
$21,437,500 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
2.5%
|
1,201,150
|
$21,020,125 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
2.1%
|
996,083
|
$17,431,453 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2%
|
954,726
|
$16,709,000 | — | 30 Sep 2025 | |
| Parkman Healthcare Partners LLC |
13F
|
Company |
1.6%
|
773,304
|
$13,532,820 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
1.4%
|
655,416
|
$11,469,780 | — | 30 Sep 2025 | |
| TCG Crossover Management, LLC |
13F
|
Company |
1.4%
|
650,000
|
$11,375,000 | — | 30 Sep 2025 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
1.3%
|
627,667
|
$10,984,173 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1%
|
473,932
|
$8,295,948 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.76%
|
358,121
|
$6,267,118 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
0.67%
|
319,274
|
$5,587,295 | — | 30 Sep 2025 | |
| Schonfeld Strategic Advisors LLC |
13F
|
Company |
0.6%
|
282,677
|
$4,946,847 | — | 30 Sep 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
0.6%
|
282,624
|
$4,945,920 | — | 30 Sep 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
0.59%
|
277,777
|
$4,861,098 | — | 30 Sep 2025 | |
| Soleus Capital Management, L.P. |
13F
|
Company |
0.58%
|
275,000
|
$4,812,500 | — | 30 Sep 2025 | |
| Opaleye Management Inc. |
13F
|
Company |
0.53%
|
253,000
|
$4,427,500 | — | 30 Sep 2025 | |
| Longaeva Partners L.P. |
13F
|
Company |
0.47%
|
224,433
|
$3,927,578 | — | 30 Sep 2025 | |
| PFM Health Sciences, LP |
13F
|
Company |
0.47%
|
221,505
|
$3,876,338 | — | 30 Sep 2025 | |
| SECTORAL ASSET MANAGEMENT INC |
13F
|
Company |
0.41%
|
194,898
|
$3,410,715 | — | 30 Sep 2025 | |
| Tetragon Partners GP Ltd |
13F
|
Company |
0.38%
|
177,840
|
$3,112,200 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.36%
|
170,006
|
$2,975,105 | — | 30 Sep 2025 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.35%
|
165,000
|
$2,887,500 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.28%
|
133,265
|
$2,332,138 | — | 30 Sep 2025 | |
| TD ASSET MANAGEMENT INC |
13F
|
Company |
0.25%
|
118,792
|
$2,078,860 | — | 30 Sep 2025 | |
| Burkehill Global Management, LP |
13F
|
Company |
0.21%
|
100,000
|
$1,750,000 | — | 30 Sep 2025 | |
| ExodusPoint Capital Management, LP |
13F
|
Company |
0.21%
|
100,000
|
$1,750,000 | — | 30 Sep 2025 | |
| DAFNA Capital Management LLC |
13F
|
Company |
0.18%
|
85,000
|
$1,487,500 | — | 30 Sep 2025 | |
| Hudson Bay Capital Management LP |
13F
|
Company |
0.18%
|
85,000
|
$1,487,500 | — | 30 Sep 2025 | |
| SCHRODER INVESTMENT MANAGEMENT GROUP |
13F
|
Company |
0.18%
|
83,766
|
$1,502,762 | — | 30 Sep 2025 | |
| Murchinson Ltd. |
13F
|
Company |
0.17%
|
80,000
|
$1,400,000 | — | 30 Sep 2025 | |
| STEMPOINT CAPITAL LP |
13F
|
Company |
0.16%
|
75,000
|
$1,312,500 | — | 30 Sep 2025 | |
| PLATINUM INVESTMENT MANAGEMENT LTD |
13F
|
Company |
0.15%
|
69,428
|
$1,214,990 | — | 30 Sep 2025 | |
| FMR LLC |
13F
|
Company |
0.15%
|
68,976
|
$1,207,080 | — | 30 Sep 2025 |
Institutional Holders of MBX Biosciences, Inc. - COMMON STOCK (MBX) as of Q4 2025
As of 31 Dec 2025,
MBX Biosciences, Inc. - COMMON STOCK (MBX) was held by
138 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
48,428,720 shares.
The largest 10 holders included
Frazier Life Sciences Management, L.P., ORBIMED ADVISORS LLC, NEA Management Company, LLC, WELLINGTON MANAGEMENT GROUP LLP, Deep Track Capital, LP, BlackRock, Inc., NVP ASSOCIATES, LLC, EcoR1 Capital, LLC, VANGUARD GROUP INC, and Driehaus Capital Management LLC.
This page lists
138
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
117
Q4 2025 holders
138
Holder diff
21
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.