LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2023 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
LIXT on Nasdaq
Shares outstanding
2,666,933
Price per share
$3.91
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
755,383
Total reported value
$2,968,653
% of total 13F portfolios
0%
Share change
+316,642
Value change
+$1,130,402
Number of holders
17
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
INTRACOASTAL CAPITAL, LLC 5% $181,780 138,763 Mitchell P. Kopin 11 Feb 2025
Orca Capital AG 4.5% -45% $157,216 -$127,568 120,012 -45% Orca Capital AG 14 Feb 2025

As of 31 Dec 2025, 17 institutional investors reported holding 755,383 shares of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT). This represents 28% of the company’s total 2,666,933 outstanding shares.

Top 21 Institutional Shareholders

The largest institutional shareholders of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) together control 28% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
SCOTIA CAPITAL INC. 9.7% 258,713 0% $1,016,742
RENAISSANCE TECHNOLOGIES LLC 4% 107,500 +47% 0% $422,475
Federation des caisses Desjardins du Quebec 3.5% 93,380 +84% 0% $366,983
VANGUARD GROUP INC 2.8% 74,944 +54% 0% $294,530
DRW Securities, LLC 2% 54,126 +12% 0.02% $212,715
GEODE CAPITAL MANAGEMENT, LLC 2% 52,163 +26% 0% $204,999
Ethos Financial Group, LLC 0.93% 24,808 0% 0.01% $97,495
STATE STREET CORP 0.65% 17,396 0% 0% $68,366
TWO SIGMA INVESTMENTS, LP 0.57% 15,174 0% $59,634
XTX Topco Ltd 0.55% 14,545 0% $57,162
CITADEL ADVISORS LLC 0.53% 14,093 0% $55,385
AXXCESS WEALTH MANAGEMENT, LLC 0.52% 13,771 0% $54,120
Atlas Legacy Advisors, LLC 0.52% 13,771 0% 0.01% $54,120
UBS Group AG 0.03% 756 -95% 0% $2,971
SBI Securities Co., Ltd. 0.01% 190 0% 0% $747
BANK OF AMERICA CORP /DE/ 0% 52 -62% 0% $205
CITIGROUP INC 0% 1 -97% 0% $4
Tower Research Capital LLC (TRC) 0% 0 -100% $0
HighTower Advisors, LLC 0% 0 -100% $0
OSAIC HOLDINGS, INC. 0% 0 -100% $0
Clear Street Group Inc. 0% 0 -100% $0

Institutional Holders of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 755,383 $2,968,653 +$1,130,402 $3.93 17
2025 Q3 438,741 $2,207,346 +$1,384,461 $5.03 16
2025 Q2 163,636 $148,054 -$163,058 $0.90 10
2025 Q1 300,011 $384,657 -$81,359 $1.21 9
2024 Q4 297,557 $607,533 +$138,617 $2.03 10
2024 Q3 215,532 $409,125 +$72,342 $1.87 7
2024 Q2 178,383 $424,174 +$88,625 $2.37 6
2024 Q1 138,296 $467,369 +$81,413 $3.38 6
2023 Q4 114,289 $267,989 +$177,089 $2.34 6
2023 Q3 37,983 $92,809 +$15,777 $2.45 6
2023 Q2 17,340 $101,452 +$101,452 $5.88 5