LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2023 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
LIXT on Nasdaq
Shares outstanding
2,666,933
Price per share
$3.93
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
438,741
Total reported value
$2,207,346
% of total 13F portfolios
0%
Share change
+275,105
Value change
+$1,384,461
Number of holders
16
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
INTRACOASTAL CAPITAL, LLC 5% $181,780 138,763 Mitchell P. Kopin 11 Feb 2025
Orca Capital AG 4.5% -45% $157,216 -$127,568 120,012 -45% Orca Capital AG 14 Feb 2025

As of 30 Sep 2025, 16 institutional investors reported holding 438,741 shares of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT). This represents 16% of the company’s total 2,666,933 outstanding shares.

Top 17 Institutional Shareholders

The largest institutional shareholders of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) together control 16% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
HighTower Advisors, LLC 3.7% 99,432 0% 0% $500,143
RENAISSANCE TECHNOLOGIES LLC 2.7% 73,150 0% $367,945
Federation des caisses Desjardins du Quebec 1.9% 50,850 0% $255,776
VANGUARD GROUP INC 1.8% 48,533 0% $244,121
DRW Securities, LLC 1.8% 48,481 0.01% $243,859
GEODE CAPITAL MANAGEMENT, LLC 1.6% 41,441 +100% 0% $208,447
Ethos Financial Group, LLC 0.93% 24,808 0% 0.01% $124,784
STATE STREET CORP 0.65% 17,396 0% $87,502
UBS Group AG 0.63% 16,747 +1406% 0% $84,237
Atlas Legacy Advisors, LLC 0.52% 13,771 0% 0.01% $69,268
OSAIC HOLDINGS, INC. 0.12% 3,215 0% $16,651
Tower Research Capital LLC (TRC) 0.02% 452 -86% 0% $2,274
SBI Securities Co., Ltd. 0.01% 190 -7.3% 0% $956
BANK OF AMERICA CORP /DE/ 0.01% 138 +13% 0% $694
Clear Street Group Inc. 0% 100 0% 0% $503
CITIGROUP INC 0% 37 0% $186
RAYMOND JAMES FINANCIAL INC 0% 0 -100% $0

Institutional Holders of LIXTE BIOTECHNOLOGY HOLDINGS, INC. - Common Stock, par value $0.0001 per share (LIXT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 24,808 $97,495 $3.93 1
2025 Q3 438,741 $2,207,346 +$1,384,461 $5.03 16
2025 Q2 163,636 $148,054 -$163,058 $0.90 10
2025 Q1 300,011 $384,657 -$81,359 $1.21 9
2024 Q4 297,557 $607,533 +$138,617 $2.03 10
2024 Q3 215,532 $409,125 +$72,342 $1.87 7
2024 Q2 178,383 $424,174 +$88,625 $2.37 6
2024 Q1 138,296 $467,369 +$81,413 $3.38 6
2023 Q4 114,289 $267,989 +$177,089 $2.34 6
2023 Q3 37,983 $92,809 +$15,777 $2.45 6
2023 Q2 17,340 $101,452 +$101,452 $5.88 5