LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX)

Q: What does CUSIP 528872302 represent in this 13F holders report?

CUSIP 528872302 is the security identifier for LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share used to aggregate holder disclosures.

Q: How many institutions held LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share in Q4 2021?

108 institutional investors reported LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share for Q4 2021. Use the holders table for investor-level position and value details.

CUSIP: 528872302

Q4 2021 13F Holders as of 31 Dec 2021

Type / Class: Equity / Common Stock, par value $0.001 per share
Shares outstanding: 427,442,892
Total 13F shares: 121,559,642
Share change: -321,051
Total reported value: $478,894,149
Put/Call ratio: 133%
Price per share: $3.94
Number of holders: 108
Value change: -$1,466,109
Number of buys: 58
Number of sells: 39

Quarterly Holders Quick Answers

What is CUSIP 528872302?
CUSIP 528872302 identifies LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2022
Previous quarter: Q3 2021

Recent filing periods for CUSIP 528872302:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Artal Group S.A.	13F	Company	17%	71,178,364	$342,368,000	—	30 Sep 2021	13F
BVF INC/IL	13F	Company	3.4%	14,360,000	$69,072,000	—	30 Sep 2021	13F
FMR LLC	13F	Company	1.5%	6,461,356	$31,079,000	—	30 Sep 2021	13F
BlackRock Finance, Inc.	13F	Company	1.1%	4,650,670	$22,369,000	—	30 Sep 2021	13F
VANGUARD GROUP INC	13F	Company	0.93%	3,985,180	$19,168,000	—	30 Sep 2021	13F
D. E. Shaw & Co., Inc.	13F	Company	0.75%	3,216,048	$15,470,000	—	30 Sep 2021	13F
NEA Management Company, LLC	13F	Company	0.56%	2,382,286	$11,459,000	—	30 Sep 2021	13F
PINNACLE ASSOCIATES LTD	13F	Company	0.49%	2,097,647	$10,090,000	—	30 Sep 2021	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.28%	1,193,922	$5,742,000	—	30 Sep 2021	13F
JPMORGAN CHASE & CO	13F	Company	0.27%	1,157,610	$5,568,000	—	30 Sep 2021	13F
STATE STREET CORP	13F	Company	0.26%	1,101,753	$5,299,000	—	30 Sep 2021	13F
Eversept Partners, LP	13F	Company	0.2%	872,694	$4,197,658	—	30 Sep 2021	13F
NORTHERN TRUST CORP	13F	Company	0.16%	688,078	$3,309,000	—	30 Sep 2021	13F
NOMURA HOLDINGS INC	13F	Company	0.16%	665,746	$3,213,000	—	30 Sep 2021	13F
Nuveen Asset Management, LLC	13F	Company	0.14%	583,300	$2,834,000	—	30 Sep 2021	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.13%	552,963	$2,660,000	—	30 Sep 2021	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.12%	495,438	$2,383,000	—	30 Sep 2021	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.11%	475,794	$2,289,000	—	30 Sep 2021	13F
BRIDGEWAY CAPITAL MANAGEMENT, LLC	13F	Company	0.09%	380,092	$1,828,000	—	30 Sep 2021	13F
Integral Health Asset Management, LLC	13F	Company	0.08%	350,000	$1,684,000	—	30 Sep 2021	13F
PANAGORA ASSET MANAGEMENT INC	13F	Company	0.07%	289,154	$1,391,000	—	30 Sep 2021	13F
Bank of New York Mellon Corp	13F	Company	0.06%	260,990	$1,255,000	—	30 Sep 2021	13F
Russell Investments Group, Ltd.	13F	Company	0.06%	242,187	$1,164,000	—	30 Sep 2021	13F
AQR CAPITAL MANAGEMENT LLC	13F	Company	0.05%	203,359	$978,000	—	30 Sep 2021	13F
PRINCIPAL FINANCIAL GROUP INC	13F	Company	0.05%	193,412	$930,000	—	30 Sep 2021	13F
STATE OF WISCONSIN INVESTMENT BOARD	13F	Company	0.04%	159,200	$766,000	—	30 Sep 2021	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.03%	131,349	$632,000	—	30 Sep 2021	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	0.03%	129,568	$623,000	—	30 Sep 2021	13F
Swiss National Bank	13F	Company	0.03%	127,300	$612,000	—	30 Sep 2021	13F
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	13F	Company	0.03%	126,917	$610,000	—	30 Sep 2021	13F
LOS ANGELES CAPITAL MANAGEMENT LLC	13F	Company	0.03%	119,199	$573,000	—	30 Sep 2021	13F
STIFEL FINANCIAL CORP	13F	Company	0.03%	115,914	$558,000	—	30 Sep 2021	13F
WINTON GROUP Ltd	13F	Company	0.03%	112,120	$539,000	—	30 Sep 2021	13F
TUDOR INVESTMENT CORP ET AL	13F	Company	0.03%	108,541	$522,000	—	30 Sep 2021	13F
MORGAN STANLEY	13F	Company	0.02%	99,508	$479,000	—	30 Sep 2021	13F
NATIXIS ADVISORS, LLC	13F	Company	0.02%	94,537	$455,000	—	30 Sep 2021	13F
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	13F	Company	0.02%	94,222	$453,000	—	30 Sep 2021	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.02%	89,913	$432,000	—	30 Sep 2021	13F
RHUMBLINE ADVISERS	13F	Company	0.02%	83,991	$404,000	—	30 Sep 2021	13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	13F	Company	0.02%	83,888	$404,000	—	30 Sep 2021	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	0.02%	83,874	$403,435	—	30 Sep 2021	13F
Vontobel Holding Ltd.	13F	Company	0.02%	80,000	$385,000	—	30 Sep 2021	13F
PARAMETRIC PORTFOLIO ASSOCIATES LLC	13F	Company	0.02%	78,798	$379,000	—	30 Sep 2021	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.02%	78,037	$375,000	—	30 Sep 2021	13F
SALEM INVESTMENT COUNSELORS INC	13F	Company	0.02%	73,000	$351,000	—	30 Sep 2021	13F
SG Americas Securities, LLC	13F	Company	0.01%	59,992	$289,000	—	30 Sep 2021	13F
SIMPLEX TRADING, LLC	13F	Company	0.01%	59,274	$258,000	—	30 Sep 2021	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	0.01%	50,111	$241,000	—	30 Sep 2021	13F
CITADEL ADVISORS LLC	13F	Company	0.01%	46,856	$225,000	—	30 Sep 2021	13F
Ergoteles LLC	13F	Company	0.01%	46,300	$223,000	—	30 Sep 2021	13F

Institutional Holders of LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX) as of Q4 2021

As of 31 Dec 2021, LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX) was held by 108 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 121,559,642 shares. The largest 10 holders included Artal Group S.A., BVF INC/IL, FMR LLC, BlackRock Inc., VANGUARD GROUP INC, D. E. Shaw & Co., Inc., NEA Management Company, LLC, PINNACLE ASSOCIATES LTD, STATE STREET CORP, and GEODE CAPITAL MANAGEMENT, LLC. This page lists 108 institutional shareholders reporting positions in this security for the Q4 2021 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

Q4 2021 holders

108

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 Value $	Q4 2021 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.