| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 14% | -10% | $198,668,637 | +$209,610 | 4,265,106 | +0.11% | RA Capital Management, L.P. | 05 Nov 2025 |
| FMR LLC | 12% | -21% | $59,243,480 | -$9,208,416 | 3,702,718 | -13% | FMR LLC | 31 Dec 2025 |
| BlackRock, Inc. | 4.9% | -4% | $24,603,568 | +$1,517,744 | 1,537,723 | +6.6% | BlackRock, Inc. | 31 Dec 2025 |
| Point72 Asset Management, L.P. | 4.8% | $63,244,042 | 1,357,751 | Steven A. Cohen | 30 Sep 2025 | |||
| Paradigm Biocapital Advisors LP | 3.8% | -28% | $50,001,813 | -$16,133,961 | 1,073,461 | -24% | Paradigm BioCapital Advisors LP | 30 Sep 2025 |
| Versant Venture Capital VI, L.P. | 3.4% | -18% | $48,936,901 | -$6,192,532 | 1,050,599 | -11% | Versant Venture Capital VI, L.P. | 05 Nov 2025 |
As of 31 Dec 2025, 154 institutional investors reported holding 35,024,505 shares of LENZ Therapeutics, Inc. - Common Stock, par value $0.00001 per share (LENZ). This represents 112% of the company’s total 31,378,962 outstanding shares.
The largest institutional shareholders of LENZ Therapeutics, Inc. - Common Stock, par value $0.00001 per share (LENZ) together control 92% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 13% | 4,178,823 | 0% | 0.69% | $66,861,168 |
| FMR LLC | 12% | 3,702,718 | +4141% | 0% | $59,243,480 |
| Alpha Wave Global, LP | 12% | 3,612,211 | 0% | 7.1% | $57,795,376 |
| Versant Venture Management, LLC | 8.5% | 2,656,888 | 0% | 28% | $42,510,208 |
| BlackRock, Inc. | 5.4% | 1,692,006 | +15% | 0% | $27,072,096 |
| UBS Group AG | 5% | 1,571,738 | +31% | 0% | $25,147,808 |
| VANGUARD GROUP INC | 4.2% | 1,321,202 | -0.68% | 0% | $21,139,232 |
| FRANKLIN RESOURCES INC | 3.5% | 1,096,334 | +87% | 0% | $17,541,344 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | 1,023,542 | +308% | 0% | $16,378,000 |
| 72 Investment Holdings, LLC | 3.2% | 1,017,751 | 0% | 32% | $16,284,016 |
| TANG CAPITAL MANAGEMENT LLC | 2.8% | 865,169 | -3.6% | 0.68% | $13,842,704 |
| INTRINSIC EDGE CAPITAL MANAGEMENT LLC | 1.8% | 569,705 | 1.8% | $9,115,280 | |
| MILLENNIUM MANAGEMENT LLC | 1.7% | 539,348 | 0.01% | $8,629,568 | |
| STATE STREET CORP | 1.6% | 510,749 | +22% | 0% | $8,171,984 |
| C WorldWide Group Holding A/S | 1.6% | 500,000 | 0.14% | $8,000,000 | |
| Squarepoint Ops LLC | 1.6% | 491,898 | +448% | 0.02% | $7,870,368 |
| Aberdeen Group plc | 1.6% | 489,432 | +274% | 0.01% | $7,830,912 |
| Alyeska Investment Group, L.P. | 1.5% | 463,495 | +91% | 0.02% | $7,415,920 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.5% | 461,075 | +1.4% | 0% | $7,378,622 |
| Granahan Investment Management, LLC | 1.4% | 431,100 | +125% | 0.3% | $6,897,600 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 1.3% | 398,566 | 0% | 0.01% | $6,377,000 |
| Candriam S.C.A. | 1.2% | 374,932 | +64% | 0.03% | $5,999,167 |
| PRIMECAP MANAGEMENT CO/CA/ | 1.2% | 372,200 | 0% | $5,955,200 | |
| TWO SIGMA INVESTMENTS, LP | 0.94% | 293,446 | +388% | 0.01% | $4,695,136 |
| Vestal Point Capital, LP | 0.88% | 275,000 | 0.16% | $4,400,000 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 35,024,505 | $560,808,387 | -$79,567,911 | $16.00 | 154 |
| 2025 Q3 | 29,140,610 | $1,355,578,952 | +$224,910,234 | $46.58 | 166 |
| 2025 Q2 | 24,727,156 | $725,109,733 | +$107,969,187 | $29.31 | 113 |
| 2025 Q1 | 21,072,237 | $541,761,121 | +$29,092,976 | $25.71 | 105 |
| 2024 Q4 | 19,863,850 | $573,239,116 | +$35,341,897 | $28.87 | 94 |
| 2024 Q3 | 18,735,645 | $444,795,067 | -$1,423,016 | $23.74 | 78 |
| 2024 Q2 | 18,913,542 | $327,016,869 | +$45,118,057 | $17.29 | 63 |
| 2024 Q1 | 16,171,755 | $361,085,230 | +$360,723,016 | $22.33 | 54 |