Security key
501147102
Krystal Biotech, Inc. - Common Stock, $0.00001 par value ("Common Stock") (KRYS)
CUSIP: 501147102
Q3 2025 13F Holders as of 30 Sep 2025
- Type / Class
- Equity / Common Stock, $0.00001 par value ("Common Stock")
- Shares outstanding
- 29,463,330
- Total 13F shares
- 27,965,722
- Share change
- +339,223
- Total reported value
- $4,936,825,964
- Put/Call ratio
- 260%
- Price per share
- $176.53
- Number of holders
- 281
- Value change
- +$84,621,791
- Number of buys
- 147
- Number of sells
- 118
Report period
Q3 2025
Institutions
281
Top holders
10
KRYS full security history
Newer quarter: Q4 2025
Previous quarter: Q2 2025
Krystal Biotech, Inc. SEC filings
Krystal Biotech, Inc. company facts
Broader feeds
Reporting periods
Holder history for CUSIP 501147102
Recent filing periods:
Top shareholders of KRYS - Krystal Biotech, Inc. - Common Stock, $0.00001 par value ("Common Stock") (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| STATE STREET CORP |
13D/G
13F
|
STATE STREET CORPORATION · Company |
4.4%
|
1,278,975
|
$218,154,766 | $0 | 31 Dec 2024 | |
| FMR LLC |
13F
|
Company |
15%
|
4,334,761
|
$595,856,258 | — | 30 Jun 2025 | |
| BlackRock, Inc. |
13F
|
Company |
13%
|
3,845,155
|
$528,555,006 | — | 30 Jun 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
9.6%
|
2,822,888
|
$388,034,184 | — | 30 Jun 2025 | |
| Avoro Capital Advisors LLC |
13F
|
Company |
9%
|
2,660,000
|
$365,643,600 | — | 30 Jun 2025 | |
| Capital World Investors |
13F
|
Company |
3.2%
|
942,249
|
$129,521,548 | — | 30 Jun 2025 | |
| Soleus Capital Management, L.P. |
13F
|
Company |
3.1%
|
922,958
|
$126,869,807 | — | 30 Jun 2025 | |
| BRAIDWELL LP |
13F
|
Company |
2.5%
|
727,811
|
$100,044,900 | — | 30 Jun 2025 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
2.3%
|
688,460
|
$94,635,712 | — | 30 Jun 2025 | |
| Redmile Group, LLC |
13F
|
Company |
2.3%
|
663,471
|
$91,200,724 | — | 30 Jun 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
2.1%
|
619,547
|
$85,173,528 | — | 30 Jun 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
1.8%
|
533,023
|
$73,269,342 | — | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1.8%
|
530,361
|
$72,903,423 | — | 30 Jun 2025 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
1.7%
|
505,889
|
$69,541,512 | — | 30 Jun 2025 | |
| NORGES BANK |
13F
|
Company |
0.96%
|
282,706
|
$38,860,767 | — | 30 Jun 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.89%
|
261,383
|
$35,931,000 | — | 30 Jun 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.85%
|
251,408
|
$34,558,544 | — | 30 Jun 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.84%
|
246,180
|
$33,839,903 | — | 30 Jun 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.8%
|
234,421
|
$32,223,630 | — | 30 Jun 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.8%
|
234,320
|
$32,209,628 | — | 30 Jun 2025 | |
| FIRST TRUST ADVISORS LP |
13F
|
Company |
0.75%
|
222,370
|
$30,566,980 | — | 30 Jun 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.64%
|
188,019
|
$25,845,091 | — | 30 Jun 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.54%
|
160,517
|
$22,064,598 | — | 30 Jun 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.51%
|
150,616
|
$20,703,675 | — | 30 Jun 2025 | |
| SEGALL BRYANT & HAMILL, LLC |
13F
|
Company |
0.5%
|
148,614
|
$20,428,480 | — | 30 Jun 2025 | |
| READYSTATE ASSET MANAGEMENT LP |
13F
|
Company |
0.5%
|
147,980
|
$20,341,331 | — | 30 Jun 2025 | |
| PRINCIPAL FINANCIAL GROUP INC |
13F
|
Company |
0.48%
|
140,883
|
$19,365,777 | — | 30 Jun 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.44%
|
130,537
|
$17,943,616 | — | 30 Jun 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.41%
|
121,812
|
$16,744,277 | — | 30 Jun 2025 | |
| TimesSquare Capital Management, LLC |
13F
|
Company |
0.39%
|
114,204
|
$15,698,482 | — | 30 Jun 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.38%
|
112,382
|
$15,448,028 | — | 30 Jun 2025 | |
| S SQUARED TECHNOLOGY, LLC |
13F
|
Company |
0.37%
|
109,215
|
$15,012,694 | — | 30 Jun 2025 | |
| Aberdeen Group plc |
13F
|
Company |
0.37%
|
108,518
|
$14,916,884 | — | 30 Jun 2025 | |
| Logos Global Management LP |
13F
|
Company |
0.34%
|
100,000
|
$13,746,000 | — | 30 Jun 2025 | |
| UBS Group AG |
13F
|
Company |
0.33%
|
97,240
|
$13,366,610 | — | 30 Jun 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.32%
|
92,871
|
$12,766,047 | — | 30 Jun 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.31%
|
91,153
|
$12,529,891 | — | 30 Jun 2025 | |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.31%
|
91,099
|
$12,522,469 | — | 30 Jun 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.3%
|
89,800
|
$12,343,908 | — | 30 Jun 2025 | |
| PUBLIC SECTOR PENSION INVESTMENT BOARD |
13F
|
Company |
0.29%
|
86,688
|
$11,916,132 | — | 30 Jun 2025 | |
| C WorldWide Group Holding A/S |
13F
|
Company |
0.29%
|
85,809
|
$11,795,000 | — | 30 Jun 2025 | |
| VICTORY CAPITAL MANAGEMENT INC |
13F
|
Company |
0.27%
|
80,123
|
$11,013,708 | — | 30 Jun 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.24%
|
70,888
|
$9,744,265 | — | 30 Jun 2025 | |
| RHUMBLINE ADVISERS |
13F
|
Company |
0.24%
|
70,753
|
$9,725,678 | — | 30 Jun 2025 | |
| RAYMOND JAMES FINANCIAL INC |
13F
|
Company |
0.23%
|
68,735
|
$9,448,313 | — | 30 Jun 2025 | |
| Legal & General Group Plc |
13F
|
Company |
0.23%
|
68,393
|
$9,401,304 | — | 30 Jun 2025 | |
| Handelsbanken Fonder AB |
13F
|
Company |
0.23%
|
66,800
|
$9,182,000 | — | 30 Jun 2025 | |
| Decheng Capital LLC |
13F
|
Company |
0.22%
|
66,000
|
$9,072,360 | — | 30 Jun 2025 | |
| VOYA INVESTMENT MANAGEMENT LLC |
13F
|
Company |
0.22%
|
63,993
|
$8,796,478 | — | 30 Jun 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.21%
|
62,835
|
$8,637,298 | — | 30 Jun 2025 |
Institutional Holders of Krystal Biotech, Inc. - Common Stock, $0.00001 par value ("Common Stock") (KRYS) as of Q3 2025
As of 30 Sep 2025,
Krystal Biotech, Inc. - Common Stock, $0.00001 par value ("Common Stock") (KRYS) was held by
281 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
27,965,722 shares.
The largest 10 holders included
FMR LLC, BlackRock, Inc., VANGUARD GROUP INC, Avoro Capital Advisors LLC, STATE STREET CORP, Soleus Capital Management, L.P., Capital World Investors, Frazier Life Sciences Management, L.P., Redmile Group, LLC, and CITADEL ADVISORS LLC.
This page lists
282
institutional shareholders reporting positions in this security
for the Q3 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
274
Q3 2025 holders
281
Holder diff
7
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 Value $ | Q3 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.