Krystal Biotech, Inc. - Common Stock, $0.00001 par value ("Common Stock") (KRYS)

CUSIP: 501147102

Q4 2024 13F Holders as of 31 Dec 2024

Holder snapshot 7 signals
Share change
-537,627
Put/Call ratio
60%
SEC-reported price per share
$156.66
Number of holders
264
Value change
-$92,533,890
Number of buys
123
Open additional details 1 more signal available
Number of sells
146
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
29,463,330

Security key

501147102

Report period

Q4 2024

Institutions

264

Top holders

10

Ownership snapshot

Top reported holders of KRYS - Krystal Biotech, Inc. - Common Stock, $0.00001 par value ("Common Stock") (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
STATE STREET CORP
Disclosed value leader
FMR LLC
Comparable rows
15/15
Latest evidence
30 Sep 2024
13F 13D/G Lead comparable stake: 4.4% 13D/G row: STATE STREET CORP Showing 1-6 of 15 holder rows.

Quick read

STATE STREET CORP leads the comparable SEC ownership view at 4.4%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens STATE STREET CORP's linked filing trail.
Comparable ownership Top 5
STATE STREET CORP 4.4%
FMR LLC 15%
BlackRock, Inc. 14%
VANGUARD GROUP INC 9.7%
Avoro Capital Advisors LLC 8.9%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
STATE STREET CORP
13F 13D/G
Company · STATE STREET CORPORATION
4.4%
from 13D/G
$264,455,186
1,452,811 shares
30 Sep 2024
FMR LLC
13F
Company
13F
15%
$781,433,128
4,292,881 shares
30 Sep 2024
BlackRock, Inc.
13F
Company
13F
14%
$726,868,180
3,993,123 shares
30 Sep 2024
VANGUARD GROUP INC
13F
Company
13F
9.7%
$518,738,900
2,849,744 shares
30 Sep 2024
Avoro Capital Advisors LLC
13F
Company
13F
8.9%
$477,323,071
2,622,222 shares
30 Sep 2024
Frazier Life Sciences Management, L.P.
13F
Company
13F
3.4%
$179,929,374
988,460 shares
30 Sep 2024
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2024

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
264
Shares
27,774,030
Rows available
264
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2024 vs Q3 2024 Across Filers

Q3 2024 holders
281
Q4 2024 holders
264
Holder diff
-17
Investor Q3 2024 Shares Q4 2024 Shares Share Diff Share Chg % Q3 2024 value Q4 2024 value Value change Value Chg %
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