| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 20% | $383,922,060 | 11,971,377 | RA Capital Management, L.P. | 06 Mar 2025 | |||
| JANUS HENDERSON GROUP PLC | 10% | +31% | $147,469,714 | +$38,459,199 | 6,033,949 | +35% | JANUS HENDERSON GROUP PLC | 31 Oct 2025 |
| FMR LLC | 5.8% | $48,484,949 | 3,512,384 | FMR LLC | 31 Dec 2025 | |||
| BlackRock, Inc. | 5.7% | $77,284,838 | 3,345,664 | BlackRock, Inc. | 30 Jun 2025 | |||
| Paradigm Biocapital Advisors LP | 4.9% | -18% | $73,444,489 | -$14,982,559 | 2,920,258 | -17% | Paradigm BioCapital Advisors LP | 30 Jun 2025 |
| Adage Capital Management, L.P. | 4.3% | -21% | $63,503,750 | -$13,499,262 | 2,525,000 | -18% | Adage Capital Management, L.P. | 30 Jun 2025 |
As of 30 Sep 2025, 168 institutional investors reported holding 65,054,632 shares of Janux Therapeutics, Inc. - COMMON STOCK (JANX). This represents 107% of the company’s total 60,558,345 outstanding shares.
The largest institutional shareholders of Janux Therapeutics, Inc. - COMMON STOCK (JANX) together control 91% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 18% | 11,189,693 | 0% | 3.4% | $273,476,097 |
| FMR LLC | 15% | 9,056,062 | +1.9% | 0.01% | $221,330,155 |
| JANUS HENDERSON GROUP PLC | 7.8% | 4,701,112 | +5.4% | 0.05% | $114,988,241 |
| BlackRock, Inc. | 6.2% | 3,730,994 | +9.6% | 0% | $91,185,492 |
| Paradigm Biocapital Advisors LP | 4.8% | 2,920,258 | 0% | 2.1% | $71,371,106 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4.6% | 2,775,000 | +9.9% | 0.11% | $67,821,000 |
| VANGUARD GROUP INC | 4% | 2,417,104 | +10% | 0% | $59,074,022 |
| STATE STREET CORP | 3.1% | 1,891,465 | +36% | 0% | $46,227,405 |
| ORBIMED ADVISORS LLC | 2.9% | 1,766,100 | +46% | 1% | $43,163,484 |
| Point72 Asset Management, L.P. | 2.8% | 1,710,200 | -20% | 0.09% | $41,797,288 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.1% | 1,265,556 | -29% | 0% | $30,931,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.8% | 1,083,864 | +20% | 0% | $26,494,551 |
| Woodline Partners LP | 1.7% | 1,026,938 | -17% | 0.12% | $25,098,365 |
| T. Rowe Price Investment Management, Inc. | 1.6% | 972,691 | 0.01% | $23,773,000 | |
| READYSTATE ASSET MANAGEMENT LP | 1.6% | 960,379 | +38% | 1.1% | $23,471,663 |
| Logos Global Management LP | 1.5% | 935,000 | -6.5% | 2.3% | $22,851,400 |
| FRANKLIN RESOURCES INC | 1.5% | 887,755 | -17% | 0.01% | $21,696,730 |
| Prosight Management, LP | 1.4% | 865,350 | +1.3% | 5.1% | $21,149,154 |
| Cormorant Asset Management, LP | 1.4% | 850,000 | -43% | 1.4% | $20,774,000 |
| CITADEL ADVISORS LLC | 1.3% | 802,784 | -35% | 0.02% | $19,620,041 |
| WELLINGTON MANAGEMENT GROUP LLP | 1.2% | 701,604 | +42% | 0% | $17,147,203 |
| TANG CAPITAL MANAGEMENT LLC | 1.2% | 700,000 | +250% | 0.66% | $17,108,000 |
| GOLDMAN SACHS GROUP INC | 1.1% | 655,108 | +88% | 0% | $16,010,840 |
| First Turn Management, LLC | 1.1% | 639,699 | +43% | 2.3% | $15,634,244 |
| MPM BIOIMPACT LLC | 1% | 614,282 | 0% | 2.5% | $15,013,052 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 137,263 | $1,893,755 | +$650,187 | $13.80 | 4 |
| 2025 Q3 | 65,054,632 | $1,589,759,767 | -$4,062,568 | $24.44 | 168 |
| 2025 Q2 | 65,389,958 | $1,510,522,459 | -$28,053,981 | $23.10 | 169 |
| 2025 Q1 | 66,482,175 | $1,805,570,973 | -$17,647,630 | $27.00 | 179 |
| 2024 Q4 | 64,089,510 | $3,430,809,553 | +$1,001,839,547 | $53.54 | 213 |
| 2024 Q3 | 45,621,730 | $2,072,353,785 | +$42,332,014 | $45.43 | 158 |
| 2024 Q2 | 44,723,442 | $1,873,142,325 | +$107,659,314 | $41.89 | 153 |
| 2024 Q1 | 42,327,541 | $1,593,608,078 | +$334,250,630 | $37.65 | 118 |
| 2023 Q4 | 33,501,695 | $359,539,970 | -$17,204,195 | $10.73 | 64 |
| 2023 Q3 | 35,112,124 | $353,984,587 | +$45,518,472 | $10.08 | 57 |
| 2023 Q2 | 30,508,831 | $362,117,070 | -$408,523 | $11.87 | 54 |
| 2023 Q1 | 30,541,873 | $369,527,936 | +$18,629,245 | $12.10 | 48 |
| 2022 Q4 | 28,954,042 | $381,308,644 | -$7,758,264 | $13.17 | 49 |
| 2022 Q3 | 29,548,436 | $400,093,845 | +$8,918,649 | $13.54 | 45 |
| 2022 Q2 | 28,911,820 | $352,963,471 | +$6,297,905 | $12.21 | 43 |
| 2022 Q1 | 28,388,419 | $407,113,023 | +$11,406,319 | $14.34 | 46 |
| 2021 Q4 | 27,496,946 | $541,627,745 | +$19,103,067 | $19.73 | 46 |
| 2021 Q3 | 26,499,088 | $571,208,440 | +$35,499,490 | $21.63 | 44 |
| 2021 Q2 | 24,743,225 | $614,460,000 | +$614,460,000 | $24.95 | 29 |