Latest Period
Q4 2025
Security Snapshot
Innoviva, Inc. - Common Stock (INVA) Institutional Ownership
CUSIP: 45781M101
13F Institutional Holders and Ownership History from Q4 2015 to Q1 2026
Institutions Reporting
277
Shares (Excl. Options)
75,268,716
Price
$19.99
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- Type / Class
- Equity / Common Stock
- Symbol
- INVA on Nasdaq
- Shares outstanding
- 74,059,810
- Price per share
- $23.97
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 75,268,716
- Total reported value
- $1,504,054,000
- % of total 13F portfolios
- 0%
- Share change
- -295,450
- Value change
- -$3,854,061
- Number of holders
- 277
- Price from insider filings
- $23.97
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- INVA - Innoviva, Inc. - Common Stock is tracked under CUSIP 45781M101.
- 277 institutions reported positions in Q4 2025.
- 7 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 277 to 82 between Q4 2025 and Q1 2026.
- Reported value moved from $1,504,054,000 to $102,194,136.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 277 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 45781M101?
CUSIP 45781M101 identifies INVA - Innoviva, Inc. - Common Stock in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 45781M101:
Significant Owners of Innoviva, Inc. - Common Stock (INVA) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 14% | $161,561,009 | 8,790,044 | BlackRock, Inc. | 31 Mar 2025 | |||
| DIMENSIONAL FUND ADVISORS LP | 5.8% | $87,164,416 | 4,360,401 | Dimensional Fund Advisors LP | 31 Dec 2025 | |||
| VANGUARD PORTFOLIO MANAGEMENT LLC | 5.8% | $99,911,868 | 4,288,063 | Vanguard Portfolio Management | 31 Mar 2026 | |||
| RENAISSANCE TECHNOLOGIES LLC | 5.6% | -24% | $84,161,338 | -$11,007,693 | 4,210,172 | -12% | Renaissance Technologies LLC | 31 Dec 2025 |
| Sarissa Capital Management LP | 4.7% | -46% | $54,515,484 | -$41,743,535 | 2,966,022 | -43% | Sarissa Capital Management LP | 13 Mar 2025 |
| FRANKLIN RESOURCES INC | 4.5% | -37% | $56,812,873 | -$32,232,054 | 2,827,918 | -36% | Franklin Resources, Inc. | 30 Jun 2025 |
| BANK OF NOVA SCOTIA | 3.4% | -36% | $39,766,841 | -$25,674,556 | 2,179,005 | -39% | BANK OF NOVA SCOTIA | 30 Sep 2025 |
As of 31 Dec 2025, 277 institutional investors reported holding 75,268,716 shares of Innoviva, Inc. - Common Stock (INVA). This represents 102% of the company’s total 74,059,810 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of Innoviva, Inc. - Common Stock (INVA) together control 79% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 14% | 10,676,775 | +13% | 0% | $213,428,735 |
| VANGUARD GROUP INC | 11% | 7,917,103 | +12% | 0% | $158,262,890 |
| DIMENSIONAL FUND ADVISORS LP | 5.9% | 4,360,401 | +0.69% | 0.02% | $87,163,721 |
| RENAISSANCE TECHNOLOGIES LLC | 5.7% | 4,210,172 | -8.2% | 0.13% | $84,161,338 |
| Sarissa Capital Management LP | 3.8% | 2,816,022 | 0% | 25% | $56,292,280 |
| STATE STREET CORP | 3.8% | 2,796,820 | +9.4% | 0% | $55,908,432 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 3.2% | 2,357,735 | -0.04% | 0.03% | $47,131,123 |
| AMERICAN CENTURY COMPANIES INC | 3% | 2,239,742 | -4.7% | 0.02% | $44,772,443 |
| SYSTEMATIC FINANCIAL MANAGEMENT LP | 2.9% | 2,114,529 | -0.09% | 1% | $42,269,447 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 1,752,438 | +11% | 0% | $35,037,822 |
| MILLENNIUM MANAGEMENT LLC | 2.2% | 1,610,305 | -1.9% | 0.02% | $32,189,997 |
| Boston Partners | 2.1% | 1,548,378 | +8.2% | 0.03% | $30,950,851 |
| BANK OF AMERICA CORP /DE/ | 2.1% | 1,519,203 | +2.9% | 0% | $30,368,868 |
| MORGAN STANLEY | 1.9% | 1,418,739 | -0.48% | 0% | $28,360,612 |
| FRANKLIN RESOURCES INC | 1.9% | 1,392,341 | -44% | 0.01% | $27,832,897 |
| MARSHALL WACE, LLP | 1.9% | 1,391,313 | -16% | 0.03% | $27,812,348 |
| Qube Research & Technologies Ltd | 1.6% | 1,215,485 | +19% | 0.03% | $24,297,545 |
| GOLDMAN SACHS GROUP INC | 1.5% | 1,121,971 | -6.8% | 0% | $22,428,200 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.4% | 1,021,146 | +17% | 0% | $20,412,709 |
| ROYCE & ASSOCIATES LP | 1.2% | 920,317 | +82% | 0.19% | $18,397,137 |
| Man Group plc | 1.1% | 850,744 | +1.5% | 0.03% | $17,006,373 |
| DEUTSCHE BANK AG\ | 1.1% | 849,868 | -13% | 0.01% | $16,988,861 |
| TWO SIGMA INVESTMENTS, LP | 1.1% | 839,865 | +61% | 0.03% | $16,788,901 |
| Invesco Ltd. | 1.1% | 832,635 | +8.8% | 0% | $16,644,373 |
| NORTHERN TRUST CORP | 0.94% | 698,075 | -0.81% | 0% | $13,954,520 |
Institutional Holders of Innoviva, Inc. - Common Stock (INVA) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 4,388,376 | $102,194,136 | +$6,174,471 | $23.30 | 82 |
| 2025 Q4 | 75,268,716 | $1,504,054,000 | -$3,854,061 | $19.99 | 277 |
| 2025 Q3 | 75,643,785 | $1,380,602,840 | +$38,742,270 | $18.25 | 258 |
| 2025 Q2 | 73,417,387 | $1,474,711,295 | +$116,321,442 | $20.09 | 262 |
| 2025 Q1 | 67,633,455 | $1,226,352,727 | -$65,481,448 | $18.13 | 242 |
| 2024 Q4 | 71,206,628 | $1,235,729,006 | -$33,745,075 | $17.35 | 232 |
| 2024 Q3 | 72,724,658 | $1,408,399,207 | -$6,610,982 | $19.31 | 218 |
| 2024 Q2 | 73,015,739 | $1,197,761,490 | +$10,463,125 | $16.40 | 211 |
| 2024 Q1 | 72,694,460 | $1,107,843,660 | +$99,075,247 | $15.24 | 212 |
| 2023 Q4 | 72,573,080 | $1,164,203,770 | +$63,189,944 | $16.04 | 196 |
| 2023 Q3 | 68,693,599 | $892,392,778 | -$22,727,129 | $12.99 | 190 |
| 2023 Q2 | 70,560,931 | $897,697,524 | +$5,686,644 | $12.73 | 195 |
| 2023 Q1 | 70,133,864 | $788,914,212 | -$68,444,416 | $11.25 | 190 |
| 2022 Q4 | 76,159,713 | $1,009,107,733 | -$15,174,194 | $13.25 | 207 |
| 2022 Q3 | 77,664,187 | $901,816,839 | -$29,481,242 | $11.61 | 205 |
| 2022 Q2 | 79,110,636 | $1,167,851,153 | +$39,101,463 | $14.76 | 210 |
| 2022 Q1 | 76,829,353 | $1,486,418,139 | +$109,661,115 | $19.35 | 229 |
| 2021 Q4 | 71,053,972 | $1,225,707,895 | -$1,592,577 | $17.25 | 214 |
| 2021 Q3 | 70,672,928 | $1,180,620,752 | +$11,972,161 | $16.71 | 201 |
| 2021 Q2 | 70,026,546 | $939,538,747 | -$4,685,915 | $13.41 | 178 |
| 2021 Q1 | 70,471,430 | $842,135,790 | -$7,853,594 | $11.95 | 172 |
| 2020 Q4 | 71,430,338 | $884,974,564 | -$21,967,754 | $12.39 | 186 |
| 2020 Q3 | 73,482,176 | $767,828,808 | -$31,660,968 | $10.45 | 198 |
| 2020 Q2 | 75,517,998 | $1,055,743,951 | +$13,098,913 | $13.98 | 196 |
| 2020 Q1 | 75,121,400 | $883,887,357 | -$1,323,036 | $11.76 | 186 |
| 2019 Q4 | 74,877,048 | $1,060,091,363 | +$22,044,768 | $14.16 | 187 |
| 2019 Q3 | 73,826,539 | $777,854,497 | -$47,938,215 | $10.54 | 196 |
| 2019 Q2 | 77,798,281 | $1,132,492,436 | -$30,802,433 | $14.56 | 209 |
| 2019 Q1 | 80,563,499 | $1,130,282,265 | +$3,340,155 | $14.03 | 225 |
| 2018 Q4 | 79,657,490 | $1,389,190,626 | +$80,546,811 | $17.45 | 228 |
| 2018 Q3 | 74,961,548 | $1,142,723,664 | +$1,604,798 | $15.24 | 206 |
| 2018 Q2 | 75,086,543 | $1,036,283,572 | -$2,296,796 | $13.80 | 213 |
| 2018 Q1 | 74,853,392 | $1,247,816,407 | -$35,818,114 | $16.67 | 219 |
| 2017 Q4 | 76,681,490 | $1,088,142,875 | -$60,644,329 | $14.19 | 192 |
| 2017 Q3 | 80,940,917 | $1,142,428,501 | +$70,034,700 | $14.12 | 197 |
| 2017 Q2 | 76,090,264 | $974,133,268 | -$89,459,991 | $12.80 | 157 |
| 2017 Q1 | 82,090,102 | $1,135,196,429 | +$95,398,109 | $13.83 | 157 |
| 2016 Q4 | 88,475,513 | $946,752,523 | +$19,379,566 | $10.70 | 142 |
| 2016 Q3 | 86,562,029 | $950,952,385 | -$29,465,363 | $10.99 | 134 |
| 2016 Q2 | 90,196,094 | $949,874,500 | -$52,526,872 | $10.53 | 133 |
| 2016 Q1 | 95,034,776 | $1,196,492,670 | +$1,128,720,098 | $12.59 | 115 |
| 2015 Q4 | 5,373,518 | $56,634,000 | +$56,634,000 | $10.54 | 4 |