INOVIO PHARMACEUTICALS, INC. - Common Stock, $0.001 par value (INO) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2023 to Q4 2025

Type / Class
Equity / Common Stock, $0.001 par value
Symbol
INO on Nasdaq
Shares outstanding
66,777,963
Price per share
$1.61
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
32,998,133
Total reported value
$57,410,644
% of total 13F portfolios
0%
Share change
+12,296,909
Value change
+$21,093,974
Number of holders
97
Price from insider filings
$1.61
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of INOVIO PHARMACEUTICALS, INC. - Common Stock, $0.001 par value (INO) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FMR LLC 15% $19,200,995 9,846,664 FMR LLC 28 Nov 2025
JANUS HENDERSON GROUP PLC 10% +63% $12,999,275 +$6,630,068 6,666,295 +104% JANUS HENDERSON GROUP PLC 28 Nov 2025
Adage Capital Management, L.P. 10% $12,911,301 5,517,650 Adage Capital Management, L.P. 30 Sep 2025
Alyeska Investment Group, L.P. 6% -19% $6,400,000 4,000,000 0% Alyeska Investment Group, L.P. 31 Dec 2025
HIGHBRIDGE CAPITAL MANAGEMENT LLC 9.2% $6,794,333 3,633,333 Highbridge Capital Management, LLC 31 Dec 2024
VANGUARD GROUP INC 5% -9.5% $5,769,107 +$2,238,719 3,315,579 +63% The Vanguard Group 31 Dec 2025
Stonepine Capital Management, LLC 3.8% -28% $2,683,444 -$900,721 1,434,997 -25% Stonepine Capital Management, LLC 31 Mar 2025
Deep Track Capital, LP 2.4% $3,076,623 1,314,796 Deep Track Capital, LP 30 Sep 2025
BlackRock, Inc. 1.5% -80% $1,099,608 -$3,642,379 537,627 -77% BlackRock, Inc. 30 Jun 2025

As of 31 Dec 2025, 97 institutional investors reported holding 32,998,133 shares of INOVIO PHARMACEUTICALS, INC. - Common Stock, $0.001 par value (INO). This represents 49% of the company’s total 66,777,963 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of INOVIO PHARMACEUTICALS, INC. - Common Stock, $0.001 par value (INO) together control 48% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FMR LLC 15% 9,846,664 +756753% 0% $17,133,195
VANGUARD GROUP INC 5% 3,315,580 +22% 0% $5,769,110
JANUS HENDERSON GROUP PLC 5% 3,308,406 +1.3% 0% $5,773,168
ADAGE CAPITAL PARTNERS GP, L.L.C. 3.8% 2,553,571 -26% 0.01% $4,443,214
Boxer Capital Management, LLC 3.6% 2,420,122 +5.2% 0.92% $4,211,012
D. E. Shaw & Co., Inc. 3.3% 2,231,811 +177% 0% $3,883,351
ADAR1 Capital Management, LLC 2.2% 1,485,008 0.19% $2,583,914
MILLENNIUM MANAGEMENT LLC 2.1% 1,403,379 -29% 0% $2,441,879
GEODE CAPITAL MANAGEMENT, LLC 1.2% 769,356 +41% 0% $1,339,699
BlackRock, Inc. 0.93% 617,869 +24% 0% $1,075,092
RENAISSANCE TECHNOLOGIES LLC 0.83% 553,164 -32% 0% $962,505
DIADEMA PARTNERS LP 0.8% 533,682 0.55% $928,607
GSA CAPITAL PARTNERS LLP 0.69% 459,828 +3.8% 0.07% $800,000
TWO SIGMA INVESTMENTS, LP 0.48% 322,739 +11% 0% $561,566
NORTHERN TRUST CORP 0.45% 299,984 +26% 0% $521,973
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.38% 250,950 +390% 0% $436,653
683 Capital Management, LLC 0.37% 248,790 0.04% $432,895
STATE STREET CORP 0.37% 247,410 +33% 0% $430,493
OMERS ADMINISTRATION Corp 0.33% 223,000 0% $388,020
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.26% 173,000 0.01% $301,020
UBS Group AG 0.26% 170,579 -42% 0% $296,808
XTX Topco Ltd 0.25% 167,037 -21% 0.01% $290,644
Persistent Asset Partners Ltd 0.21% 142,164 0.12% $247,365
JACOBS LEVY EQUITY MANAGEMENT, INC 0.2% 130,792 +640% 0% $227,578
Qube Research & Technologies Ltd 0.17% 115,470 +245% 0% $200,918

Institutional Holders of INOVIO PHARMACEUTICALS, INC. - Common Stock, $0.001 par value (INO) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 32,998,133 $57,410,644 +$21,093,974 $1.74 97
2025 Q3 20,711,886 $48,449,935 +$25,433,676 $2.34 98
2025 Q2 10,168,502 $20,694,831 -$6,577,397 $2.04 101
2025 Q1 13,600,161 $22,159,691 +$51,992 $1.63 105
2024 Q4 13,346,624 $24,424,740 +$7,463,553 $1.83 100
2024 Q3 8,566,045 $49,511,575 +$2,096,827 $5.78 95
2024 Q2 8,056,972 $65,100,837 +$29,640,224 $8.08 92
2024 Q1 4,044,287 $56,123,192 +$53,680,856 $13.88 83
2023 Q4 298,900 $152,940 +$152,930 $0.51 7