Security Snapshot

IO Biotech, Inc. - Common Stock, par value $0.001 per share (IOBT) Institutional Ownership

CUSIP: 449778109

13F Institutional Holders and Ownership History from Q4 2021 to Q4 2025

Latest Period

Q4 2025

Institutions Reporting

22

Shares (Excl. Options)

7,848,183

Price

$0.61

Type / Class
Equity / Common Stock, par value $0.001 per share
Symbol
IOBT on Nasdaq
Shares outstanding
73,755,848
Price per share
$0.22
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
7,848,183
Total reported value
$4,778,900
% of total 13F portfolios
0%
Share change
-2,047,692
Value change
-$1,143,305
Number of holders
22
Price from insider filings
$0.22
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

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Quick Takeaways

  • IOBT - IO Biotech, Inc. - Common Stock, par value $0.001 per share is tracked under CUSIP 449778109.
  • 22 institutions reported positions in Q4 2025.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 21 to 22 between Q3 2025 and Q4 2025.
  • Reported value moved from $3,589,663 to $4,778,900.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Official SEC Source

Backed by Form 13F

Ownership context comes from SEC Form 13F and, when available, Schedule 13D/13G filings.

See Original Filing

Investment Quick Answers

What is CUSIP 449778109?
CUSIP 449778109 identifies IOBT - IO Biotech, Inc. - Common Stock, par value $0.001 per share in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of IO Biotech, Inc. - Common Stock, par value $0.001 per share (IOBT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Chernett Jorey 6.3% +20% $2,317,201 +$543,849 4,543,532 +31% Chernett Jorey 31 Dec 2025
Point72 Asset Management, L.P. 5.6% $2,452,108 4,027,112 Point72 Asset Management, L.P. 05 Feb 2026
Samsara BioCapital, L.P. 3.8% $2,578,946 2,631,578 Samsara BioCapital, L.P. 31 Dec 2024
Novo Holdings A/S 3.3% -57% $1,827,160 -$1,859,215 2,469,135 -50% Novo Holdings A/S 21 Jan 2026
HBM Healthcare Investments (Cayman) Ltd. 3.3% -61% $535,467 -$679,689 2,433,943 -56% HBM Healthcare Investments (Cayman) Ltd. 02 Apr 2026

As of 31 Dec 2025, 22 institutional investors reported holding 7,848,183 shares of IO Biotech, Inc. - Common Stock, par value $0.001 per share (IOBT). This represents 11% of the company’s total 73,755,848 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of IO Biotech, Inc. - Common Stock, par value $0.001 per share (IOBT) together control 11% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
NOVO HOLDINGS A/S 3.4% 2,512,453 0% 0.12% $1,529,833
Ikarian Capital, LLC 1.9% 1,386,565 -9.1% 0.11% $844,279
BANK OF AMERICA CORP /DE/ 1.1% 799,953 0% 0% $486,371
MORGAN STANLEY 0.73% 539,182 -19% 0% $328,308
Beacon Pointe Advisors, LLC 0.69% 506,000 0% $308,104
BOOTHBAY FUND MANAGEMENT, LLC 0.61% 451,852 -24% 0.01% $275,133
Dauntless Investment Group, LLC 0.61% 451,641 1.1% $275,004
MARSHALL WACE, LLP 0.58% 429,338 -59% 0% $261,897
RENAISSANCE TECHNOLOGIES LLC 0.28% 207,601 -62% 0% $126,408
MILLENNIUM MANAGEMENT LLC 0.19% 138,716 -90% 0% $84,464
CITIGROUP INC 0.15% 111,447 +8526% 0% $67,860
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.1% 75,000 0% 0% $45,668
TWO SIGMA SECURITIES, LLC 0.06% 44,757 0% $27,253
UBS Group AG 0.06% 43,578 +521% 0% $26,539
GEODE CAPITAL MANAGEMENT, LLC 0.05% 33,307 0% 0% $20,280
Hilton Capital Management, LLC 0.03% 25,510 0% 0% $15,533
ADAR1 Capital Management, LLC 0.03% 24,964 0% $15,201
PKS Advisory Services, LLC 0.03% 20,000 +2.6% 0% $12,178
Virtu Financial LLC 0.03% 19,078 -51% 0% $12,000
XTX Topco Ltd 0.02% 15,864 -91% 0% $9,660
Scientech Research LLC 0.02% 11,255 0% $6,853
SBI Securities Co., Ltd. 0% 122 0% 0% $74
GOLDMAN SACHS GROUP INC 0% 0 -100% $0
Quadrature Capital Ltd 0% 0 -100% $0
Point72 Asset Management, L.P. 0% 0 -100% $0

Institutional Holders of IO Biotech, Inc. - Common Stock, par value $0.001 per share (IOBT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 7,848,183 $4,778,900 -$1,143,305 $0.61 22
2025 Q3 9,895,875 $3,589,663 -$13,417,589 $0.36 21
2025 Q2 18,182,707 $25,273,480 -$1,285,024 $1.39 26
2025 Q1 19,066,617 $20,781,978 -$660,538 $1.09 21
2024 Q4 19,692,862 $18,114,763 -$4,833,042 $0.92 26
2024 Q3 23,591,882 $24,769,965 -$2,959,503 $1.05 19
2024 Q2 26,183,049 $30,634,167 -$1,443,320 $1.17 19
2024 Q1 27,341,910 $47,354,293 -$3,558,302 $1.73 17
2023 Q4 29,400,721 $55,273,224 +$999,356 $1.88 18
2023 Q3 29,668,665 $41,702,613 +$24,426,263 $1.41 19
2023 Q2 12,246,779 $23,953,554 -$3,111,706 $1.96 15
2023 Q1 13,917,553 $26,081,803 -$1,175,062 $1.88 17
2022 Q4 14,281,285 $32,846,954 -$2,578,155 $2.30 17
2022 Q3 15,335,530 $41,559,000 -$326,875 $2.71 20
2022 Q2 15,453,557 $72,167,000 +$2,681,635 $4.67 18
2022 Q1 14,858,852 $76,863,500 -$1,060,884 $5.30 19
2021 Q4 12,982,583 $82,349,000 +$82,349,000 $6.40 19

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