13F reference period
Q2 2026
CUSIP: 423494103
13F reference period
Q2 2026
Institutions Reporting
56
Shares (Excl. Options)
Price
$36.73
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 56 institutions filings for Q2 2026.
Security key
423494103
13F reference period
Q2 2026
13F holders
56
13D/G owners
6
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 423494103:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 10% | +31% | $145,181,130 | +$34,985,587 | 4,871,850 | +32% | FMR LLC | 30 Oct 2026 |
| Novo Holdings A/S | 9% | $165,173,530 | 4,180,550 | Novo Holdings A/S | 30 Jun 2026 | |||
| Capital International Investors | 7.7% | $142,389,141 | 3,603,876 | Capital International Investors | 30 Jun 2026 | |||
| Avoro Capital Advisors LLC | 7.1% | $130,313,304 | 3,298,236 | Behzad Aghazadeh | 30 Jun 2026 | |||
| Sofinnova Crossover II S.L.P. | 5.4% | $99,217,986 | 2,511,212 | Sofinnova Crossover II SLP | 30 Jun 2026 | |||
| Invus Global Management, LLC | 5.1% | $93,489,945 | 2,366,235 | Raymond Debbane | 03 Aug 2026 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 17% | 7,808,627 | 2.5% | $286,810,870 | |
| NOVO HOLDINGS A/S | 8.9% | 4,180,550 | 9% | $153,551,602 | |
| FMR LLC | 7.9% | 3,697,837 | 0.01% | $135,821,553 | |
| Capital International Investors | 7.7% | 3,603,876 | 0.03% | $132,370,365 | |
| Deep Track Capital, LP | 7.7% | 3,602,093 | 1.9% | $132,304,876 | |
| Siren, L.L.C. | 4.5% | 2,086,834 | 1.6% | $76,649,413 | |
| Avoro Capital Advisors LLC | 4.1% | 1,925,150 | 0.63% | $70,710,760 | |
| Bain Capital Life Sciences Investors, LLC | 3.5% | 1,650,000 | 3.6% | $60,604,500 | |
| JPMORGAN CHASE & CO | 2.5% | 1,152,420 | 0% | $42,328,387 | |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.7% | 780,758 | 0% | $28,677,241 | |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.6% | 746,040 | 0% | $27,404,000 | |
| Driehaus Capital Management LLC | 1.5% | 715,791 | 0.15% | $26,291,003 | |
| Rock Springs Capital Management LP | 1.2% | 575,432 | 1% | $21,135,617 | |
| Bellevue Group AG | 1.2% | 550,000 | 0.43% | $20,201,500 | |
| CITADEL ADVISORS LLC | 1.1% | 523,450 | 0.01% | $19,226,319 | |
| BlackRock, Inc. | 0.61% | 283,833 | 0% | $10,425,186 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0.59% | 275,000 | 0.11% | $10,100,750 | |
| ExodusPoint Capital Management, LP | 0.47% | 218,287 | 0.07% | $8,017,682 | |
| GEODE CAPITAL MANAGEMENT, LLC | 0.45% | 211,798 | 0% | $7,783,580 | |
| BRAIDWELL LP | 0.34% | 160,000 | 0.22% | $5,876,800 | |
| MARSHALL WACE, LLP | 0.33% | 154,674 | 0% | $5,681,176 | |
| Woodline Partners LP | 0.32% | 150,040 | 0.02% | $5,510,969 | |
| Affinity Asset Advisors, LLC | 0.29% | 138,030 | 0.25% | $5,069,842 | |
| Ensign Peak Advisors, Inc | 0.25% | 115,394 | 0.01% | $4,238,422 | |
| VANGUARD FIDUCIARY TRUST CO | 0.24% | 112,499 | 0% | $4,132,088 |
Quarter history
Holder count, reported shares/value, and median price by quarter.