FRACTYL HEALTH, INC. - Common Stock, $0.00001 par value per share (GUTS) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2024 to Q4 2025

Type / Class
Equity / Common Stock, $0.00001 par value per share
Symbol
GUTS on Nasdaq
Shares outstanding
153,300,724
Price per share
$2.12
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
112,417,176
Total reported value
$247,341,068
% of total 13F portfolios
0.01%
Share change
+20,935,027
Value change
+$46,907,144
Number of holders
96
Price from insider filings
$2.12
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of FRACTYL HEALTH, INC. - Common Stock, $0.00001 par value per share (GUTS) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Nantahala Capital Management, LLC 10% $21,120,969 13,283,628 Nantahala Capital Management, LLC 30 Sep 2025
SILVERARC CAPITAL MANAGEMENT, LLC 8% $16,854,000 10,600,000 SilverArc Capital Management, LLC 30 Sep 2025
Alyeska Investment Group, L.P. 5% -47% $17,142,854 -$12,708,835 7,619,046 -43% Alyeska Investment Group, L.P. 31 Dec 2025
683 Capital Management, LLC 5.3% $9,975,000 7,125,000 683 Capital Management, LLC 10 Oct 2025
Mithril LP 4.7% $14,535,230 6,460,102 Ajay Royan 31 Dec 2025
BVP VII SPECIAL OPPORTUNITY FUND LP 9.9% $5,725,081 4,770,901 Deer VII & Co. L.P. 31 Dec 2024
HCC Manager LLC 3.4% $10,279,710 4,673,870 CVF, LLC 04 Feb 2026
MAVERICK CAPITAL LTD 3.1% $6,755,102 4,248,492 Maverick Capital, Ltd. 30 Sep 2025
BlackRock, Inc. 3.7% -30% $2,148,031 -$832,331 1,790,026 -28% BlackRock, Inc. 31 Mar 2025

As of 31 Dec 2025, 96 institutional investors reported holding 112,417,176 shares of FRACTYL HEALTH, INC. - Common Stock, $0.00001 par value per share (GUTS). This represents 73% of the company’s total 153,300,724 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of FRACTYL HEALTH, INC. - Common Stock, $0.00001 par value per share (GUTS) together control 63% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Nantahala Capital Management, LLC 7.1% 10,846,440 -11% 1.4% $23,862,168
SILVERARC CAPITAL MANAGEMENT, LLC 6.4% 9,840,041 -7.2% 3.1% $21,648,090
683 Capital Management, LLC 3.9% 6,047,620 +30% 1.1% $13,304,764
VANGUARD GROUP INC 3.9% 6,028,179 +214% 0% $13,261,994
MARSHALL WACE, LLP 3.9% 5,926,745 +235% 0.01% $13,038,839
Woodline Partners LP 3.6% 5,506,771 +0% 0.05% $12,114,896
Catalio Capital Management, LP 3.6% 5,491,866 +5.3% 2.3% $12,082,105
General Catalyst Group Management, LLC 3.2% 4,884,193 0% 4.8% $10,745,225
Deer Management Co. LLC 3.1% 4,770,901 0% 1% $10,495,982
HCC Manager LLC 3% 4,673,870 -0% 100% $10,282,514
MAVERICK CAPITAL LTD 2.8% 4,248,492 0% 0.1% $9,346,682
Alyeska Investment Group, L.P. 2.5% 3,809,523 -33% 0.02% $8,380,951
GOLDMAN SACHS GROUP INC 2.2% 3,425,197 +598% 0% $7,535,434
Pale Fire Capital SE 2.1% 3,209,942 0.91% $7,061,872
BlackRock, Inc. 1.4% 2,083,318 +174% 0% $4,583,299
Atom Investors LP 1.2% 1,883,018 0.33% $4,142,640
RENAISSANCE TECHNOLOGIES LLC 1.2% 1,863,051 +140% 0.01% $4,098,712
JANE STREET GROUP, LLC 1.2% 1,862,600 0% $4,097,720
MILLENNIUM MANAGEMENT LLC 1.2% 1,861,418 +357% 0% $4,095,120
M28 Capital Management LP 1.2% 1,856,117 0% 3% $4,083,457
TWO SIGMA INVESTMENTS, LP 1.2% 1,840,136 0.01% $4,048,299
D. E. Shaw & Co., Inc. 0.94% 1,442,745 +390% 0% $3,174,039
TWO SIGMA ADVISERS, LP 0.85% 1,298,700 0.01% $2,857,140
GEODE CAPITAL MANAGEMENT, LLC 0.82% 1,263,855 +329% 0% $2,781,939
BANK OF AMERICA CORP /DE/ 0.78% 1,192,236 +1245% 0% $2,622,919

Institutional Holders of FRACTYL HEALTH, INC. - Common Stock, $0.00001 par value per share (GUTS) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 112,417,176 $247,341,068 +$46,907,144 $2.20 96
2025 Q3 91,496,818 $145,426,221 +$101,430,257 $1.59 72
2025 Q2 27,689,590 $44,866,375 +$4,734,618 $1.62 60
2025 Q1 24,943,878 $29,694,209 -$1,452,284 $1.19 65
2024 Q4 25,900,702 $53,356,352 -$1,300,474 $2.06 63
2024 Q3 25,848,760 $65,398,566 -$1,520,664 $2.53 60
2024 Q2 19,294,685 $82,271,503 -$17,164,738 $4.27 43
2024 Q1 25,158,859 $185,344,559 +$150,757,910 $7.40 41