Latest Period
Q1 2026
Security Snapshot
Definium Therapeutics, Inc. - Common Shares (DFTX) Institutional Ownership
CUSIP: 24477V105
13F Institutional Holders and Ownership History from Q4 2025 to Q1 2026
Institutions Reporting
244
Shares (Excl. Options)
78,036,684
Price
$18.90
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- Security type / class
- Equity / Common Shares
- Symbol
- DFTX on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 78,036,684
- Total 13F value
- $1,474,447,042
- Portfolio coverage rank
- 0.01%
- Share change
- +64,092,654
- Value change
- +$1,211,067,091
- Number of holders
- 244
- Shares outstanding
- 99,667,774
- SEC-reported price per share
- $23.52
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
2 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- DFTX - Definium Therapeutics, Inc. - Common Shares is tracked under CUSIP 24477V105.
- 244 institutions reported positions in Q1 2026.
- 4 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 8 to 244 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $150,679,840 to $1,474,447,042.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 244 institutions filings for Q1 2026.
Security key
24477V105
Latest holder period
Q1 2026
13F holders
244
13D/G owners
4
CIK / CUSIP context first
Open Q1 2026 holders
DFTX full holder history
Definium Therapeutics, Inc. SEC filings
Definium Therapeutics, Inc. company facts
Definium Therapeutics, Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 24477V105:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
4
Security
DFTX
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Commodore Capital LP | 7.2% | 7,428,775 | Commodore Capital LP | 31 Dec 2025 | ||||
| DRIEHAUS CAPITAL MANAGEMENT LLC | 6.6% | 6,537,202 | DRIEHAUS CAPITAL MANAGEMENT LLC | 31 Dec 2025 | ||||
| Avoro Capital Advisors LLC | 5.1% | 5,000,000 | Avoro Capital Advisors LLC | 31 Dec 2025 | ||||
| Deep Track Capital, LP | 3% | -42% | $66,750,000 | -$59,553,015 | 3,000,000 | -47% | Deep Track Capital, LP | 31 Mar 2026 |
As of 31 Mar 2026, 244 institutional investors reported holding 78,036,684 shares of Definium Therapeutics, Inc. - Common Shares (DFTX). This represents 78% of the company’s total 99,667,774 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
56%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 8.5% | 8,480,230 | 0% | $160,276,347 | |
| Driehaus Capital Management LLC | 5.9% | 5,911,889 | -9.6% | 0.82% | $111,734,702 |
| Avoro Capital Advisors LLC | 5% | 5,000,000 | 0.93% | $94,500,000 | |
| JANUS HENDERSON GROUP PLC | 3.6% | 3,556,041 | 0.03% | $67,226,955 | |
| Deep Track Capital, LP | 3% | 3,000,000 | 1.2% | $56,700,000 | |
| GEODE CAPITAL MANAGEMENT, LLC | 2.5% | 2,495,399 | 0% | $47,173,387 | |
| STATE STREET CORP | 2.5% | 2,471,873 | 0% | $46,718,400 | |
| Octagon Capital Advisors LP | 2.4% | 2,440,000 | 5.1% | $46,116,000 | |
| Commodore Capital LP | 2% | 2,000,000 | 2.2% | $37,800,000 | |
| FMR LLC | 1.8% | 1,809,610 | 0% | $34,201,639 | |
| Trails Edge Capital Partners, LP | 1.7% | 1,738,110 | 7.7% | $32,850,280 | |
| GOLDMAN SACHS GROUP INC | 1.7% | 1,675,411 | 0% | $31,665,268 | |
| ArrowMark Colorado Holdings LLC | 1.6% | 1,594,717 | 0.8% | $30,140,151 | |
| CITADEL ADVISORS LLC | 1.3% | 1,333,442 | 0.02% | $25,202,054 | |
| WELLINGTON MANAGEMENT GROUP LLP | 1.3% | 1,304,749 | 0% | $24,659,758 | |
| Candriam S.C.A. | 1.3% | 1,293,629 | 0.13% | $24,449,588 | |
| Balyasny Asset Management L.P. | 1.3% | 1,274,221 | 0.05% | $24,082,777 | |
| TWO SIGMA INVESTMENTS, LP | 1.2% | 1,201,610 | 0.02% | $22,710,429 | |
| MARSHALL WACE, LLP | 1.2% | 1,200,825 | -60% | 0.02% | $22,695,593 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.2% | 1,150,000 | 0.03% | $21,735,000 | |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.1% | 1,096,978 | 0% | 0% | $20,732,884 |
| Holocene Advisors, LP | 1.1% | 1,091,967 | 0.05% | $20,638,176 | |
| AWM Investment Company, Inc. | 1.1% | 1,076,893 | -23% | 2.3% | $20,353,278 |
| Catalio Capital Management, LP | 1% | 1,037,984 | 4.1% | $19,617,898 | |
| AMERIPRISE FINANCIAL INC | 0.97% | 966,608 | 0% | $18,268,891 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
2
Latest
Q1 2026
Rows shown
1-2 of 2