CYTOKINETICS INC - COMMON STOCK (CYTK) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2014 to Q4 2025

Type / Class
Equity / COMMON STOCK
Symbol
CYTK on Nasdaq
Shares outstanding
119,358,581
Price per share
$63.54
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
140,918,559
Total reported value
$7,744,283,008
% of total 13F portfolios
0.01%
Share change
+3,340,798
Value change
+$248,284,955
Number of holders
376
Price from insider filings
$63.54
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of CYTOKINETICS INC - COMMON STOCK (CYTK) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
T. Rowe Price Investment Management, Inc. 16% +8.7% $1,049,591,620 +$82,161,518 19,097,373 +8.5% T. Rowe Price Investment Management, Inc. 30 Sep 2025
FMR LLC 11% +17% $479,911,470 +$71,598,573 13,101,596 +18% FMR LLC 31 Jul 2025
VANGUARD GROUP INC 10% $480,565,061 11,915,821 The Vanguard Group 31 Dec 2024
STATE STREET CORP 4.7% $308,728,677 5,617,334 STATE STREET CORPORATION 30 Sep 2025

As of 30 Sep 2025, 376 institutional investors reported holding 140,918,559 shares of CYTOKINETICS INC - COMMON STOCK (CYTK). This represents 118% of the company’s total 119,358,581 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of CYTOKINETICS INC - COMMON STOCK (CYTK) together control 92% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
T. Rowe Price Investment Management, Inc. 16% 19,080,496 +8.4% 0.64% $1,048,665,000
BlackRock, Inc. 13% 15,525,747 -0.97% 0.02% $853,295,069
FMR LLC 11% 13,091,647 +16% 0.04% $719,516,917
VANGUARD GROUP INC 9.9% 11,856,795 -1.1% 0.01% $651,649,453
WELLINGTON MANAGEMENT GROUP LLP 6.2% 7,408,561 -5.4% 0.07% $407,174,511
STATE STREET CORP 4.7% 5,617,334 -12% 0.01% $308,728,677
Deep Track Capital, LP 3.6% 4,300,000 +18% 6.6% $236,328,000
BANK OF AMERICA CORP /DE/ 2.6% 3,061,796 +16% 0.01% $168,276,308
GEODE CAPITAL MANAGEMENT, LLC 2.5% 3,040,202 +1.5% 0.01% $167,111,997
Polar Capital Holdings Plc 2.3% 2,782,930 -0.55% 0.74% $152,949,833
RTW INVESTMENTS, LP 2.3% 2,721,158 0% 1.8% $149,554,844
PRICE T ROWE ASSOCIATES INC /MD/ 2% 2,366,848 +27% 0.01% $130,083,000
UBS Group AG 1.5% 1,803,251 -41% 0.02% $99,106,675
Woodline Partners LP 1.4% 1,647,725 +676% 0.43% $90,558,966
GOLDMAN SACHS GROUP INC 1.4% 1,634,723 +28% 0.01% $89,844,376
JPMORGAN CHASE & CO 1.3% 1,542,857 +17% 0.01% $84,795,420
MORGAN STANLEY 1.3% 1,521,186 +36% 0.01% $83,604,444
NORTHERN TRUST CORP 1.2% 1,406,832 +2% 0.01% $77,319,488
Integral Health Asset Management, LLC 1.2% 1,400,000 +40% 5.6% $76,944,000
CITADEL ADVISORS LLC 1.2% 1,386,065 +6.7% 0.06% $76,178,132
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1.2% 1,373,883 +1.2% 0.01% $75,508,610
ARMISTICE CAPITAL, LLC 1% 1,196,868 -8.8% 2.1% $65,779,865
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 1% 1,192,484 +10% 5.1% $65,538,921
Capital International Investors 0.99% 1,178,780 +0.91% 0.01% $64,785,749
PRINCIPAL FINANCIAL GROUP INC 0.98% 1,174,448 -0.87% 0.03% $64,547,663

Institutional Holders of CYTOKINETICS INC - COMMON STOCK (CYTK) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 1,353,067 $85,973,005 -$33,855,761 $63.54 27
2025 Q3 140,918,559 $7,744,283,008 +$248,284,955 $54.96 376
2025 Q2 137,672,960 $4,548,776,123 +$22,757,186 $33.04 308
2025 Q1 134,841,578 $5,424,137,644 +$124,956,259 $40.19 352
2024 Q4 131,310,237 $6,182,701,180 -$305,419,938 $47.04 342
2024 Q3 135,965,538 $7,179,495,863 -$22,095,980 $52.80 343
2024 Q2 135,538,659 $7,341,546,249 +$905,298,022 $54.18 341
2024 Q1 117,698,153 $8,252,737,252 +$191,436,420 $70.11 385
2023 Q4 114,281,648 $9,541,763,681 +$330,415,688 $83.49 344
2023 Q3 109,279,375 $3,219,564,491 +$24,845,219 $29.46 248
2023 Q2 108,724,328 $3,548,383,679 -$11,513,808 $32.62 252
2023 Q1 108,867,212 $3,829,923,005 +$81,444,143 $35.19 259
2022 Q4 106,503,991 $4,877,881,469 +$56,105,064 $45.82 271
2022 Q3 104,802,748 $5,076,619,614 -$48,250,542 $48.45 271
2022 Q2 105,856,945 $4,159,716,153 +$425,134,262 $39.29 255
2022 Q1 95,536,900 $3,516,647,768 +$153,742,395 $36.81 233
2021 Q4 91,314,688 $4,159,253,639 +$41,291,377 $45.58 244
2021 Q3 90,207,271 $3,220,707,699 +$496,552,275 $35.74 208
2021 Q2 75,530,208 $1,494,840,686 +$7,258,934 $19.79 184
2021 Q1 74,824,822 $1,739,406,944 +$58,909,832 $23.26 185
2020 Q4 72,927,397 $1,515,101,565 +$2,994,280 $20.78 174
2020 Q3 68,793,341 $1,486,919,340 +$223,796,678 $21.65 176
2020 Q2 57,902,469 $1,364,739,639 +$106,180,554 $23.57 155
2020 Q1 55,577,469 $655,114,415 +$7,494,589 $11.79 140
2019 Q4 54,967,200 $583,186,084 +$110,961,493 $10.61 138
2019 Q3 44,469,174 $506,043,282 +$8,118,835 $11.38 142
2019 Q2 43,758,616 $492,255,849 +$60,765,739 $11.25 131
2019 Q1 39,149,048 $316,789,384 +$2,575,674 $8.09 128
2018 Q4 39,751,282 $251,199,067 +$585,312 $6.32 125
2018 Q3 38,573,613 $379,945,234 +$12,021,170 $9.85 115
2018 Q2 37,497,804 $311,245,360 +$6,016,664 $8.30 122
2018 Q1 36,846,990 $265,290,511 -$12,323,363 $7.20 120
2017 Q4 38,427,550 $313,274,680 -$31,796,309 $8.15 127
2017 Q3 39,538,270 $573,258,785 +$22,292,833 $14.50 128
2017 Q2 38,242,269 $462,840,533 +$119,794,762 $12.10 135
2017 Q1 28,322,853 $363,941,426 +$63,505,651 $12.85 105
2016 Q4 26,441,374 $321,178,146 -$2,239,851 $12.15 99
2016 Q3 26,660,084 $244,743,898 +$491,452 $9.18 88
2016 Q2 26,539,822 $251,857,889 +$5,257,399 $9.49 93
2016 Q1 26,628,683 $187,563,987 -$4,719,516 $7.05 105
2015 Q4 26,471,070 $276,904,125 +$56,009,005 $10.46 124
2015 Q3 21,585,148 $144,504,660 +$5,042,983 $6.69 102
2015 Q2 20,750,403 $139,436,627 +$7,715,400 $6.72 96
2015 Q1 19,599,208 $133,005,626 +$956,806 $6.78 92
2014 Q4 19,305,123 $154,537,250 +$202,262 $8.01 84
2014 Q3 19,810,554 $69,719,049 -$7,580,787 $3.52 82
2014 Q2 21,028,918 $100,514,515 -$36,406,249 $4.78 84
2014 Q1 22,477,638 $213,590,026 +$39,204,449 $9.50 104