CYTOKINETICS INC - COMMON STOCK (CYTK) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2014 to Q4 2025

Type / Class
Equity / COMMON STOCK
Symbol
CYTK on Nasdaq
Shares outstanding
122,181,876
Price per share
$65.04
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
138,449,647
Total reported value
$8,797,192,732
% of total 13F portfolios
0.01%
Share change
-3,235,045
Value change
-$178,256,905
Number of holders
424
Price from insider filings
$65.04
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of CYTOKINETICS INC - COMMON STOCK (CYTK) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
T. Rowe Price Investment Management, Inc. 14% -9.4% $1,145,186,286 -$89,267,905 17,716,372 -7.2% T. Rowe Price Investment Management, Inc. 31 Dec 2025
FMR LLC 11% +17% $479,911,470 +$71,598,573 13,101,596 +18% FMR LLC 31 Jul 2025
VANGUARD GROUP INC 10% $480,565,061 11,915,821 The Vanguard Group 31 Dec 2024
STATE STREET CORP 4.7% $308,728,677 5,617,334 STATE STREET CORPORATION 30 Sep 2025

As of 31 Dec 2025, 424 institutional investors reported holding 138,449,647 shares of CYTOKINETICS INC - COMMON STOCK (CYTK). This represents 113% of the company’s total 122,181,876 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of CYTOKINETICS INC - COMMON STOCK (CYTK) together control 87% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
T. Rowe Price Investment Management, Inc. 14% 17,716,372 -7.1% 0.71% $1,125,699,000
BlackRock, Inc. 13% 16,395,123 +5.6% 0.02% $1,041,746,107
FMR LLC 10% 12,807,752 -2.2% 0.04% $813,804,582
VANGUARD GROUP INC 9.9% 12,048,131 +1.6% 0.01% $765,538,243
WELLINGTON MANAGEMENT GROUP LLP 6.5% 7,937,063 +7.1% 0.09% $504,320,984
STATE STREET CORP 4.8% 5,825,295 +3.7% 0.01% $370,139,244
Deep Track Capital, LP 2.7% 3,336,998 -22% 4.8% $212,032,853
GEODE CAPITAL MANAGEMENT, LLC 2.5% 3,056,017 +0.52% 0.01% $194,213,741
BANK OF AMERICA CORP /DE/ 2.4% 2,941,152 -3.9% 0.01% $186,880,798
RTW INVESTMENTS, LP 2.2% 2,721,158 0% 1.7% $172,902,379
Polar Capital Holdings Plc 2% 2,422,612 -13% 0.7% $153,932,766
GOLDMAN SACHS GROUP INC 1.9% 2,371,647 +45% 0.02% $150,694,451
PRICE T ROWE ASSOCIATES INC /MD/ 1.6% 1,930,119 -18% 0.01% $122,641,000
Woodline Partners LP 1.3% 1,648,428 +0.04% 0.41% $104,741,115
JPMORGAN CHASE & CO 1.2% 1,412,797 -8.4% 0.01% $89,769,121
Integral Health Asset Management, LLC 1.1% 1,400,000 0% 4.5% $88,956,000
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1.1% 1,383,437 +0.7% 0.01% $87,903,587
NORTHERN TRUST CORP 1.1% 1,380,787 -1.9% 0.01% $87,735,208
MORGAN STANLEY 1% 1,265,301 -17% 0% $80,397,317
Capital International Investors 0.96% 1,178,780 0% 0.01% $74,899,681
CITADEL ADVISORS LLC 0.95% 1,162,937 -16% 0.05% $73,893,017
UBS Group AG 0.93% 1,131,456 -37% 0.01% $71,892,714
ARMISTICE CAPITAL, LLC 0.81% 992,766 -17% 1.5% $63,080,352
PRINCIPAL FINANCIAL GROUP INC 0.8% 976,892 -17% 0.03% $62,071,717
Frazier Life Sciences Management, L.P. 0.76% 934,642 +5% 1.6% $59,387,153

Institutional Holders of CYTOKINETICS INC - COMMON STOCK (CYTK) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 138,449,647 $8,797,192,732 -$178,256,905 $63.54 424
2025 Q3 140,922,556 $7,744,502,973 +$248,285,010 $54.96 379
2025 Q2 137,672,960 $4,548,776,123 +$22,757,186 $33.04 308
2025 Q1 134,841,578 $5,424,137,644 +$124,956,259 $40.19 352
2024 Q4 131,310,237 $6,182,701,180 -$305,419,938 $47.04 342
2024 Q3 135,965,538 $7,179,495,863 -$22,095,980 $52.80 343
2024 Q2 135,538,659 $7,341,546,249 +$905,298,022 $54.18 341
2024 Q1 117,698,153 $8,252,737,252 +$191,436,420 $70.11 385
2023 Q4 114,281,648 $9,541,763,681 +$330,415,688 $83.49 344
2023 Q3 109,279,375 $3,219,564,491 +$24,845,219 $29.46 248
2023 Q2 108,724,328 $3,548,383,679 -$11,513,808 $32.62 252
2023 Q1 108,867,212 $3,829,923,005 +$81,444,143 $35.19 259
2022 Q4 106,503,991 $4,877,881,469 +$56,105,064 $45.82 271
2022 Q3 104,802,748 $5,076,619,614 -$48,250,542 $48.45 271
2022 Q2 105,856,945 $4,159,716,153 +$425,134,262 $39.29 255
2022 Q1 95,536,900 $3,516,647,768 +$153,742,395 $36.81 233
2021 Q4 91,314,688 $4,159,253,639 +$41,291,377 $45.58 244
2021 Q3 90,207,271 $3,220,707,699 +$496,552,275 $35.74 208
2021 Q2 75,530,208 $1,494,840,686 +$7,258,934 $19.79 184
2021 Q1 74,824,822 $1,739,406,944 +$58,909,832 $23.26 185
2020 Q4 72,927,397 $1,515,101,565 +$2,994,280 $20.78 174
2020 Q3 68,793,341 $1,486,919,340 +$223,796,678 $21.65 176
2020 Q2 57,902,469 $1,364,739,639 +$106,180,554 $23.57 155
2020 Q1 55,577,469 $655,114,415 +$7,494,589 $11.79 140
2019 Q4 54,967,200 $583,186,084 +$110,961,493 $10.61 138
2019 Q3 44,469,174 $506,043,282 +$8,118,835 $11.38 142
2019 Q2 43,758,616 $492,255,849 +$60,765,739 $11.25 131
2019 Q1 39,149,048 $316,789,384 +$2,575,674 $8.09 128
2018 Q4 39,751,282 $251,199,067 +$585,312 $6.32 125
2018 Q3 38,573,613 $379,945,234 +$12,021,170 $9.85 115
2018 Q2 37,497,804 $311,245,360 +$6,016,664 $8.30 122
2018 Q1 36,846,990 $265,290,511 -$12,323,363 $7.20 120
2017 Q4 38,427,550 $313,274,680 -$31,796,309 $8.15 127
2017 Q3 39,538,270 $573,258,785 +$22,292,833 $14.50 128
2017 Q2 38,242,269 $462,840,533 +$119,794,762 $12.10 135
2017 Q1 28,322,853 $363,941,426 +$63,505,651 $12.85 105
2016 Q4 26,441,374 $321,178,146 -$2,239,851 $12.15 99
2016 Q3 26,660,084 $244,743,898 +$491,452 $9.18 88
2016 Q2 26,539,822 $251,857,889 +$5,257,399 $9.49 93
2016 Q1 26,628,683 $187,563,987 -$4,719,516 $7.05 105
2015 Q4 26,471,070 $276,904,125 +$56,009,005 $10.46 124
2015 Q3 21,585,148 $144,504,660 +$5,042,983 $6.69 102
2015 Q2 20,750,403 $139,436,627 +$7,715,400 $6.72 96
2015 Q1 19,599,208 $133,005,626 +$956,806 $6.78 92
2014 Q4 19,305,123 $154,537,250 +$202,262 $8.01 84
2014 Q3 19,810,554 $69,719,049 -$7,580,787 $3.52 82
2014 Q2 21,028,918 $100,514,515 -$36,406,249 $4.78 84
2014 Q1 22,477,638 $213,590,026 +$39,204,449 $9.50 104