| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 10% | 0% | $9,156,792 | +$1,392,249 | 5,620,422 | +18% | Nantahala Capital Management, LLC | 30 Sep 2025 |
| Sofinnova Partners SAS | 2.7% | -54% | $1,185,734 | -$1,188,000 | 1,197,711 | -50% | Sofinnova Capital VIII | 31 Mar 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 11,792,663 | $19,221,893 | +$6,863,060 | $1.63 | 45 |
| 2025 Q2 | 7,578,787 | $12,505,248 | +$3,952,656 | $1.65 | 40 |
| 2025 Q1 | 5,230,260 | $6,956,589 | +$1,241,119 | $1.33 | 35 |
| 2024 Q4 | 5,108,991 | $9,553,550 | +$495,078 | $1.87 | 34 |
| 2024 Q3 | 5,193,769 | $4,039,786 | -$775,970 | $0.7762 | 32 |
| 2024 Q2 | 6,247,425 | $4,679,876 | -$811,761 | $0.7500 | 41 |
| 2024 Q1 | 7,272,011 | $7,707,118 | -$189,424 | $1.06 | 44 |
| 2023 Q4 | 7,451,323 | $7,825,763 | -$54,129 | $1.05 | 41 |
| 2023 Q3 | 7,501,451 | $8,401,710 | -$2,281,471 | $1.12 | 40 |
| 2023 Q2 | 8,974,632 | $13,507,225 | +$1,945,492 | $1.50 | 38 |
| 2023 Q1 | 7,677,996 | $11,976,762 | +$3,808,602 | $1.56 | 41 |
| 2022 Q4 | 5,400,142 | $3,438,849 | -$3,310,463 | $0.6374 | 46 |
| 2022 Q3 | 9,314,202 | $12,384,077 | -$3,927,969 | $1.33 | 51 |
| 2022 Q2 | 11,700,511 | $25,971,549 | -$20,267,021 | $2.22 | 60 |
| 2022 Q1 | 14,236,792 | $88,111,251 | -$45,899,789 | $6.19 | 83 |
| 2021 Q4 | 19,237,596 | $242,781,654 | -$219,571,461 | $12.62 | 95 |
| 2021 Q3 | 19,191,414 | $1,759,087,977 | +$80,924,604 | $91.66 | 130 |
| 2021 Q2 | 18,545,330 | $982,908,976 | -$6,104,699 | $53.00 | 104 |
| 2021 Q1 | 18,693,040 | $673,491,454 | +$37,011,077 | $36.03 | 90 |
| 2020 Q4 | 17,656,872 | $490,520,403 | +$26,833,435 | $27.78 | 84 |
| 2020 Q3 | 16,543,535 | $826,995,550 | +$55,308,755 | $50.00 | 85 |
| 2020 Q2 | 15,442,796 | $714,739,484 | +$184,954,170 | $46.30 | 82 |
| 2020 Q1 | 11,450,501 | $522,757,976 | +$39,593,805 | $45.61 | 65 |
| 2019 Q4 | 10,588,023 | $594,414,680 | +$91,850,250 | $56.14 | 51 |
| 2019 Q3 | 5,847,617 | $144,973,494 | +$81,320,822 | $24.93 | 41 |
| 2019 Q2 | 2,421,805 | $102,945,360 | +$102,944,765 | $42.51 | 37 |