| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 10% | +1.9% | $60,117,785 | +$12,881,057 | 17,176,510 | +27% | TANG CAPITAL MANAGEMENT, LLC | 30 Sep 2025 |
| ORBIMED ADVISORS LLC | 8.9% | -19% | $41,093,984 | 15,219,994 | 0% | ORBIMED ADVISORS LLC | 13 Aug 2025 | |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 8.2% | +60% | $44,559,662 | +$21,967,265 | 14,101,159 | +97% | Suvretta Capital Management, LLC | 13 Aug 2025 |
| BlackRock, Inc. | 5.2% | +12% | $49,788,728 | +$15,426,163 | 9,271,644 | +45% | BlackRock, Inc. | 31 Dec 2025 |
| Vivo Opportunity Fund Holdings, L.P. | 5.1% | $31,485,926 | 8,995,979 | Vivo Opportunity Fund Holdings, L.P. | 30 Sep 2025 | |||
| BIOTECHNOLOGY VALUE FUND L P | 5.1% | $30,625,000 | 8,750,000 | BVF PARTNERS L P/IL | 22 Oct 2025 | |||
| Commander Aggregator, LP | 4.5% | $24,610,554 | 7,788,150 | Commander Aggregator, LP | 14 Aug 2025 | |||
| Blackstone Holdings II L.P. | 3.4% | $31,917,408 | 6,126,182 | Blackstone Alternative Asset Management Associates LLC | 31 Dec 2025 | |||
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4.4% | $11,629,931 | 5,994,810 | Adage Capital Management, L.P. | 31 Dec 2024 | |||
| MPM BioImpact LLC | 4.1% | -35% | $15,180,764 | -$7,952,556 | 5,622,505 | -34% | MPM BioImpact LLC | 30 Jun 2025 |
As of 31 Dec 2025, 168 institutional investors reported holding 163,523,220 shares of Compass Therapeutics, Inc. - Common Stock, $0.0001 par value per share (CMPX). This represents 91% of the company’s total 180,181,824 outstanding shares.
The largest institutional shareholders of Compass Therapeutics, Inc. - Common Stock, $0.0001 par value per share (CMPX) together control 79% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 9.3% | 16,790,809 | -0.13% | 4.5% | $90,166,644 |
| ORBIMED ADVISORS LLC | 8.4% | 15,219,994 | 0% | 1.7% | $81,731,368 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 7.9% | 14,182,379 | +0.58% | 1.9% | $76,159,375 |
| Vivo Capital, LLC | 5.3% | 9,545,466 | 0% | 3.3% | $51,259,152 |
| BlackRock, Inc. | 5.2% | 9,388,624 | +27% | 0% | $50,416,912 |
| VANGUARD GROUP INC | 4.5% | 8,048,374 | +14% | 0% | $43,219,768 |
| ENAVATE SCIENCES GP, LLC | 4.3% | 7,788,150 | 0% | 8.3% | $41,822,366 |
| BVF INC/IL | 4.3% | 7,764,842 | +63% | 1.4% | $41,697,202 |
| Blackstone Inc. | 3.4% | 6,126,182 | -38% | 0.14% | $32,897,597 |
| STATE STREET CORP | 2.7% | 4,890,525 | +57% | 0% | $26,262,119 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2.5% | 4,436,500 | -14% | 0.04% | $23,824,005 |
| Rock Springs Capital Management LP | 2.2% | 3,927,202 | -12% | 1.1% | $21,089,075 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 2% | 3,606,000 | 0.25% | $19,364,220 | |
| GEODE CAPITAL MANAGEMENT, LLC | 1.9% | 3,502,526 | +19% | 0% | $18,813,341 |
| Blue Owl Capital Holdings LP | 1.9% | 3,466,525 | +34% | 5.8% | $18,615,239 |
| Sofinnova Investments, Inc. | 1.9% | 3,365,446 | +66% | 0.78% | $18,072,445 |
| MILLENNIUM MANAGEMENT LLC | 1.7% | 3,109,286 | -4% | 0.01% | $16,696,866 |
| BRAIDWELL LP | 1.5% | 2,786,778 | 0.48% | $14,964,998 | |
| FMR LLC | 1.4% | 2,579,711 | -38% | 0% | $13,853,048 |
| Palo Alto Investors LP | 1.4% | 2,532,419 | 1.9% | $13,599,090 | |
| RTW INVESTMENTS, LP | 1.4% | 2,500,000 | 0% | 0.13% | $13,425,000 |
| Balyasny Asset Management L.P. | 0.88% | 1,593,275 | -44% | 0.02% | $8,555,887 |
| Birchview Capital, LP | 0.88% | 1,592,938 | +82% | 5% | $8,554,077 |
| GOLDMAN SACHS GROUP INC | 0.84% | 1,517,415 | +46% | 0% | $8,148,519 |
| Trails Edge Capital Partners, LP | 0.79% | 1,415,273 | 0% | 1.9% | $7,600,016 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 163,523,220 | $878,125,499 | +$64,761,256 | $5.37 | 168 |
| 2025 Q3 | 151,052,849 | $528,694,287 | +$149,920,554 | $3.50 | 124 |
| 2025 Q2 | 108,253,035 | $281,458,749 | +$738,261 | $2.60 | 103 |
| 2025 Q1 | 108,444,414 | $206,047,938 | +$13,824,994 | $1.90 | 107 |
| 2024 Q4 | 101,374,021 | $146,996,022 | +$1,180,763 | $1.45 | 92 |
| 2024 Q3 | 92,186,861 | $169,597,729 | +$881,089 | $1.84 | 79 |
| 2024 Q2 | 92,861,661 | $93,412,908 | -$5,271,746 | $1.00 | 81 |
| 2024 Q1 | 94,552,324 | $187,180,490 | +$18,089,983 | $1.98 | 77 |
| 2023 Q4 | 86,111,898 | $134,344,397 | -$2,317,455 | $1.56 | 76 |
| 2023 Q3 | 89,720,729 | $176,712,745 | -$1,697,948 | $1.97 | 76 |
| 2023 Q2 | 90,478,972 | $287,651,504 | +$28,216,829 | $3.18 | 72 |
| 2023 Q1 | 81,516,748 | $266,518,963 | +$1,871,389 | $3.27 | 72 |
| 2022 Q4 | 79,833,267 | $401,391,571 | +$78,919,542 | $5.03 | 54 |
| 2022 Q3 | 63,858,418 | $145,631,000 | +$3,917,942 | $2.28 | 36 |
| 2022 Q2 | 61,892,616 | $163,922,000 | +$665,806 | $2.65 | 31 |
| 2022 Q1 | 62,376,106 | $85,353,000 | -$4,074,753 | $1.37 | 33 |
| 2021 Q4 | 63,567,962 | $201,611,000 | +$198,091,000 | $3.17 | 37 |