13F reference period
Q3 2026
CUSIP: 20454B104
13F reference period
Q3 2026
Institutions Reporting
79
Shares (Excl. Options)
Price
$1.04
The headline uses the Q3 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended.
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Latest holder context comes from 79 institutions filings for Q3 2026.
Security key
20454B104
13F reference period
Q3 2026
13F holders
79
13D/G owners
11
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 20454B104:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 10% | +1.9% | $60,117,785 | +$12,881,057 | 17,176,510 | +27% | TANG CAPITAL MANAGEMENT, LLC | 30 Sep 2025 |
| ORBIMED ADVISORS LLC | 8.9% | -19% | $41,093,984 | 15,219,994 | 0% | ORBIMED ADVISORS LLC | 13 Aug 2025 | |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 8.2% | +60% | $44,559,662 | +$21,967,265 | 14,101,159 | +97% | Suvretta Capital Management, LLC | 13 Aug 2025 |
| BlackRock, Inc. | 5.2% | +12% | $49,788,728 | +$15,426,163 | 9,271,644 | +45% | BlackRock, Inc. | 31 Dec 2025 |
| Commander Aggregator, LP | 4.5% | $24,610,554 | 7,788,150 | Commander Aggregator, LP | 14 Aug 2025 | |||
| BIOTECHNOLOGY VALUE FUND L P | 4.3% | -16% | $41,076,014 | -$5,211,486 | 7,764,842 | -11% | BVF PARTNERS L P/IL | 31 Mar 2026 |
| STATE STREET CORP | 4.3% | -24% | $6,654,627 | -$1,905,515 | 7,737,938 | -22% | STATE STREET CORPORATION | 30 Sep 2026 |
| Vivo Opportunity Fund Holdings, L.P. | 4% | -22% | $15,784,585 | -$3,916,609 | 7,207,573 | -20% | Vivo Opportunity Fund Holdings, L.P. | 30 Jun 2026 |
| Blackstone Holdings II L.P. | 3.4% | $31,917,408 | 6,126,182 | Blackstone Alternative Asset Management Associates LLC | 31 Dec 2025 | |||
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 4.4% | $11,629,931 | 5,994,810 | Adage Capital Management, L.P. | 31 Dec 2024 | |||
| MPM BioImpact LLC | 4.1% | -35% | $15,180,764 | -$7,952,556 | 5,622,505 | -34% | MPM BioImpact LLC | 30 Jun 2025 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| STATE STREET CORP | 4.3% | 7,737,938 | -22% | 0% | $8,047,456 |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.3% | 5,994,782 | -2% | 0% | $6,234,573 |
| Qube Research & Technologies Ltd | 2.3% | 4,170,894 | +13% | 0% | $4,337,730 |
| GEODE CAPITAL MANAGEMENT, LLC | 2% | 3,644,115 | -4.5% | 0% | $3,790,929 |
| Vivo Capital, LLC | 1.9% | 3,423,547 | -56% | 0.39% | $3,560,489 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1.2% | 2,077,875 | -45% | 0% | $2,160,990 |
| Fisher Asset Management, LLC | 1.1% | 1,945,821 | +40% | 0% | $2,023,653 |
| MARSHALL WACE, LLP | 0.95% | 1,707,238 | +410% | 0% | $1,775,529 |
| Birchview Capital, LP | 0.88% | 1,575,000 | -6% | 0.95% | $1,638,000 |
| MORGAN STANLEY | 0.83% | 1,494,654 | +103% | 0% | $1,554,441 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 0.67% | 1,208,004 | 0% | $1,256,324 | |
| VANGUARD FIDUCIARY TRUST CO | 0.54% | 973,188 | -2.8% | 0% | $1,012,116 |
| ROYCE & ASSOCIATES LP | 0.49% | 888,393 | -34% | 0.01% | $923,929 |
| DIMENSIONAL FUND ADVISORS LP | 0.48% | 855,724 | +58% | 0% | $890,770 |
| CM Management, LLC | 0.42% | 750,000 | +36% | 0.52% | $780,000 |
| Connor, Clark & Lunn Investment Management Ltd. | 0.38% | 677,252 | +29% | 0% | $704,342 |
| Quadrature Capital Ltd | 0.35% | 638,820 | +490% | 0% | $664,373 |
| NATIXIS | 0.17% | 310,800 | +4.4% | 0% | $323,232 |
| ALPS ADVISORS INC | 0.13% | 236,892 | +30% | 0% | $246,368 |
| Rafferty Asset Management, LLC | 0.12% | 208,702 | +9.8% | 0% | $217,050 |
| PANAGORA ASSET MANAGEMENT INC | 0.11% | 202,635 | -8.8% | 0% | $210,740 |
| Creative Planning | 0.09% | 161,774 | -12% | 0% | $168,245 |
| Virtus Investment Advisers, LLC | 0.09% | 156,322 | -3% | 0.04% | $162,575 |
| DEUTSCHE BANK AG\ | 0.06% | 114,236 | -15% | 0% | $118,805 |
| GROUP ONE TRADING LLC | 0.06% | 107,068 | +31% | 0% | $111,351 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 42,554,449 | $44,259,679 | -$9,959,126 | $1.04 | 79 |
| 2026 Q2 | 165,537,068 | $362,506,628 | -$119,586,467 | $2.19 | 214 |
| 2026 Q1 | 173,194,999 | $916,047,041 | +$49,017,701 | $5.29 | 199 |
| 2025 Q4 | 164,168,134 | $881,588,986 | +$65,007,494 | $5.37 | 174 |
| 2025 Q3 | 151,052,849 | $528,694,287 | +$149,920,554 | $3.50 | 124 |
| 2025 Q2 | 108,253,035 | $281,458,749 | +$738,261 | $2.60 | 103 |
| 2025 Q1 | 108,444,414 | $206,047,938 | +$13,824,994 | $1.90 | 107 |
| 2024 Q4 | 101,374,021 | $146,996,022 | +$1,180,763 | $1.45 | 92 |
| 2024 Q3 | 92,186,861 | $169,597,729 | +$881,089 | $1.84 | 79 |
| 2024 Q2 | 92,861,661 | $93,412,908 | -$5,271,746 | $1.00 | 81 |
| 2024 Q1 | 94,552,324 | $187,180,490 | +$18,089,983 | $1.98 | 77 |
| 2023 Q4 | 86,111,898 | $134,344,397 | -$2,317,455 | $1.56 | 76 |
| 2023 Q3 | 89,720,729 | $176,712,745 | -$1,697,948 | $1.97 | 76 |
| 2023 Q2 | 90,478,972 | $287,651,504 | +$28,216,829 | $3.18 | 72 |
| 2023 Q1 | 81,516,748 | $266,518,963 | +$1,871,389 | $3.27 | 72 |
| 2022 Q4 | 79,833,267 | $401,391,571 | +$78,919,542 | $5.03 | 54 |
| 2022 Q3 | 63,858,418 | $145,631,000 | +$3,917,942 | $2.28 | 36 |
| 2022 Q2 | 61,892,616 | $163,922,000 | +$665,806 | $2.65 | 31 |
| 2022 Q1 | 62,376,106 | $85,353,000 | -$4,074,753 | $1.37 | 33 |
| 2021 Q4 | 63,567,962 | $201,611,000 | +$198,091,000 | $3.17 | 37 |