Biomea Fusion, Inc. - Common Stock, $0.0001 par value per share (BMEA) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2021 to Q4 2025

Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
BMEA on Nasdaq
Shares outstanding
79,264,970
Price per share
$1.18
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
23,229,454
Total reported value
$28,804,496
% of total 13F portfolios
0%
Share change
-2,430,758
Value change
-$7,131,468
Number of holders
59
Price from insider filings
$1.18
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Biomea Fusion, Inc. - Common Stock, $0.0001 par value per share (BMEA) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
CVI Investments, Inc. 9.9% 0% $11,927,793 +$2,131,163 7,847,232 +22% CVI Investments, Inc. 31 Dec 2025
Blue Owl Capital Holdings LP 5.9% +83% $6,765,853 +$2,965,853 4,451,219 +78% Blue Owl Capital Holdings LP 31 Dec 2025
JANUS HENDERSON GROUP PLC 5% $4,725,000 3,750,000 JANUS HENDERSON GROUP PLC 28 Nov 2025
Erdtmann Rainer M 3.9% -26% $3,450,557 -$238,721 2,782,707 -6.5% Rainer M. Erdtmann 31 Dec 2025
BAKER BROS. ADVISORS LP 4% $3,194,378 1,451,990 Baker Bros. Advisors LP 31 Dec 2024
Cormorant Asset Management, LP 1.5% -76% $2,143,436 -$5,295,734 1,060,792 -71% Chen Bihua 22 Oct 2025
BlackRock, Inc. 1.3% $1,356,467 753,551 BlackRock, Inc. 30 Jun 2025

As of 31 Dec 2025, 59 institutional investors reported holding 23,229,454 shares of Biomea Fusion, Inc. - Common Stock, $0.0001 par value per share (BMEA). This represents 29% of the company’s total 79,264,970 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Biomea Fusion, Inc. - Common Stock, $0.0001 par value per share (BMEA) together control 29% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FMR LLC 11% 8,813,359 +16% 0% $10,928,565
VANGUARD GROUP INC 3.7% 2,968,041 +37% 0% $3,680,371
Aisling Capital Management LP 2.6% 2,048,757 0% 0.53% $2,540,459
Woodline Partners LP 1.6% 1,300,834 0% 0.01% $1,613,034
MARSHALL WACE, LLP 1.5% 1,160,351 +294% 0% $1,438,835
BlackRock, Inc. 0.8% 632,065 -30% 0% $783,760
FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. 0.8% 631,465 0% 0.03% $783,018
Mariner, LLC 0.74% 585,632 +145% 0% $726,184
GEODE CAPITAL MANAGEMENT, LLC 0.71% 562,898 +26% 0% $698,126
RENAISSANCE TECHNOLOGIES LLC 0.6% 478,619 -20% 0% $593,488
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.6% 478,025 +41% 0% $592,751
TWO SIGMA INVESTMENTS, LP 0.53% 423,469 -25% 0% $525,102
UBS Group AG 0.48% 379,464 +301% 0% $470,535
MORGAN STANLEY 0.47% 372,629 -16% 0% $462,059
FEDERATED HERMES, INC. 0.39% 311,099 -46% 0% $385,763
XTX Topco Ltd 0.33% 261,072 -1.6% 0.01% $323,729
SUPERSTRING CAPITAL MANAGEMENT LP 0.32% 250,000 0% 0.17% $310,000
NORTHERN TRUST CORP 0.26% 208,965 +11% 0% $259,117
STATE STREET CORP 0.21% 165,115 +18% 0% $204,743
LMR Partners LLP 0.19% 150,000 0% $186,000
TWO SIGMA ADVISERS, LP 0.13% 105,800 -60% 0% $131,192
Marex Group plc 0.13% 100,000 0% 0% $124,000
Sculptor Capital LP 0.11% 84,800 0% 0% $105,152
Quadrature Capital Ltd 0.09% 69,932 -21% 0% $86,716
JANE STREET GROUP, LLC 0.09% 69,479 -14% 0% $86,154

Institutional Holders of Biomea Fusion, Inc. - Common Stock, $0.0001 par value per share (BMEA) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 23,229,454 $28,804,496 -$7,131,468 $1.24 59
2025 Q3 26,499,624 $53,525,349 -$11,520,176 $2.02 73
2025 Q2 28,737,423 $51,727,041 +$13,133,320 $1.80 85
2025 Q1 21,112,990 $44,967,556 -$8,154,409 $2.13 93
2024 Q4 22,924,691 $88,955,044 -$2,717,339 $3.88 106
2024 Q3 23,289,692 $235,224,566 +$5,561,482 $10.10 87
2024 Q2 23,418,825 $105,385,983 -$56,287,309 $4.50 103
2024 Q1 31,168,968 $465,919,123 +$48,952,081 $14.95 103
2023 Q4 27,900,855 $405,127,492 -$31,393,382 $14.52 99
2023 Q3 30,123,888 $414,484,591 +$4,624,066 $13.76 84
2023 Q2 29,585,977 $649,379,655 +$128,540,713 $21.95 90
2023 Q1 23,442,495 $726,954,686 +$288,071,001 $31.01 73
2022 Q4 14,476,587 $122,000,494 -$3,139,979 $8.43 54
2022 Q3 14,777,774 $144,518,000 -$26,137,812 $9.78 48
2022 Q2 17,028,866 $203,999,000 -$9,210,835 $11.98 39
2022 Q1 18,165,319 $81,000,820 +$998,154 $4.46 47
2021 Q4 17,122,645 $127,260,000 -$1,050,091 $7.45 49
2021 Q3 17,136,537 $204,513,000 +$6,120,520 $11.97 39
2021 Q2 16,466,918 $253,907,000 +$253,906,995 $15.61 44