| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Casdin Capital, LLC | 12.4% | -11% | $151,967,279 | -$19,132,500 | 5,957,165 | -11% | Casdin Capital, LLC | 15 Oct 2025 |
| T. Rowe Price Investment Management, Inc. | 8.9% | $96,485,160 | 4,246,706 | T. Rowe Price Investment Management, Inc. | 30 Jun 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 48,107,711 | $1,227,205,552 | -$40,341,783 | $25.51 | 188 |
| 2025 Q2 | 49,891,551 | $1,074,666,783 | +$46,085,035 | $21.54 | 193 |
| 2025 Q1 | 47,668,681 | $1,088,709,499 | +$20,128,588 | $22.84 | 188 |
| 2024 Q4 | 46,805,050 | $1,214,970,700 | +$32,660,204 | $25.96 | 179 |
| 2024 Q3 | 45,256,383 | $1,133,546,998 | -$37,704,401 | $25.04 | 193 |
| 2024 Q2 | 46,759,086 | $1,001,701,609 | +$52,199,509 | $21.43 | 164 |
| 2024 Q1 | 44,406,426 | $823,506,297 | -$18,755,552 | $18.55 | 148 |
| 2023 Q4 | 45,388,256 | $737,705,671 | +$37,803,026 | $16.25 | 138 |
| 2023 Q3 | 43,572,418 | $601,804,361 | +$31,718,369 | $13.81 | 152 |
| 2023 Q2 | 40,574,468 | $896,734,819 | +$40,556,636 | $22.1 | 155 |
| 2023 Q1 | 38,757,969 | $842,823,822 | +$17,191,226 | $21.75 | 165 |
| 2022 Q4 | 38,161,776 | $694,539,798 | -$10,679,652 | $18.2 | 160 |
| 2022 Q3 | 38,421,067 | $874,137,954 | +$38,798,900 | $22.75 | 169 |
| 2022 Q2 | 36,797,091 | $508,323,451 | +$12,324,863 | $13.81 | 146 |
| 2022 Q1 | 35,131,386 | $798,491,817 | -$7,596,956 | $22.73 | 155 |
| 2021 Q4 | 34,958,126 | $1,302,914,183 | +$115,722,970 | $37.27 | 165 |
| 2021 Q3 | 31,670,115 | $1,340,574,104 | +$157,430,709 | $42.32 | 159 |
| 2021 Q2 | 27,974,612 | $1,245,139,856 | +$121,193,958 | $44.51 | 130 |
| 2021 Q1 | 25,413,123 | $914,855,472 | +$45,084,655 | $36 | 130 |
| 2020 Q4 | 24,231,900 | $966,664,009 | +$97,438,296 | $39.89 | 125 |
| 2020 Q3 | 22,145,073 | $640,866,936 | +$216,554,424 | $28.94 | 104 |
| 2020 Q2 | 14,927,170 | $244,144,153 | +$49,280,131 | $16.35 | 82 |
| 2020 Q1 | 12,125,864 | $115,194,176 | +$10,152,917 | $9.5 | 73 |
| 2019 Q4 | 10,352,922 | $167,504,873 | -$1,157,792 | $16.18 | 79 |
| 2019 Q3 | 10,248,020 | $170,376,845 | +$21,192,749 | $16.63 | 78 |
| 2019 Q2 | 8,980,039 | $150,448,121 | +$6,076,613 | $16.95 | 71 |
| 2019 Q1 | 8,599,553 | $153,847,483 | +$19,590,648 | $17.89 | 65 |
| 2018 Q4 | 7,525,099 | $90,520,000 | -$6,348,673 | $12.03 | 52 |
| 2018 Q3 | 7,614,985 | $133,259,000 | +$55,383,982 | $17.5 | 51 |
| 2018 Q2 | 4,545,796 | $51,865,700 | +$32,049,888 | $11.41 | 45 |
| 2018 Q1 | 1,683,075 | $8,619,000 | -$151,371 | $5.12 | 23 |
| 2017 Q4 | 1,709,367 | $10,256,000 | +$2,569,633 | $6 | 26 |
| 2017 Q3 | 1,282,103 | $7,324,000 | +$5,380,776 | $5.71 | 19 |
| 2017 Q2 | 339,958 | $813,000 | +$183,536 | $2.4 | 8 |
| 2017 Q1 | 266,914 | $557,000 | +$91,186 | $2.09 | 8 |
| 2016 Q4 | 266,829 | $431,000 | -$33,995 | $1.6 | 11 |
| 2016 Q3 | 282,237 | $518,000 | -$124,588 | $1.84 | 10 |
| 2016 Q2 | 381,436 | $609,000 | +$39,267 | $1.6 | 9 |
| 2016 Q1 | 356,480 | $653,000 | +$28,574 | $1.83 | 9 |
| 2015 Q4 | 338,498 | $736,000 | +$10,054 | $2.2 | 7 |
| 2015 Q3 | 333,970 | $707,000 | +$93,511 | $2.12 | 6 |
| 2015 Q2 | 290,217 | $566,010 | -$196,456 | $1.95 | 5 |
| 2015 Q1 | 422,277 | $681,008 | -$329,999 | $1.61 | 9 |
| 2014 Q4 | 623,246 | $1,023,008 | -$91,795 | $1.64 | 7 |
| 2014 Q3 | 579,026 | $1,216,311 | +$668 | $2.1 | 7 |
| 2014 Q2 | 577,808 | $1,318,011 | +$1,318,011 | $2.28 | 8 |