ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2024 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.001 per shares (the "Shares")
Symbol
ASMB on Nasdaq
Shares outstanding
15,738,333
Price per share
$31.74
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
6,388,221
Total reported value
$217,142,264
% of total 13F portfolios
0%
Share change
-271,240
Value change
-$5,177,941
Number of holders
36
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Commodore Capital LP 9.9% $29,281,576 1,615,981 Commodore Capital LP 08 Aug 2025
RA CAPITAL MANAGEMENT, L.P. 9.5% $28,392,908 1,530,615 RA Capital Management, L.P. 11 Aug 2025
JANUS HENDERSON GROUP PLC 8.2% $44,444,160 1,341,508 JANUS HENDERSON GROUP PLC 28 Nov 2025
Farallon Capital Partners, L.P. 7.8% +7.1% $38,963,707 +$2,763,919 1,227,590 +7.6% Dapice Joshua J. 31 Dec 2025
Schornstein Alexander 3.5% -65% $10,082,352 -$3,424,144 543,523 -25% Alexander Schornstein 11 Aug 2025
ARMISTICE CAPITAL, LLC 10% $5,252,553 289,876 Armistice Capital, LLC 30 Jun 2025

As of 31 Dec 2025, 36 institutional investors reported holding 6,388,221 shares of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB). This represents 41% of the company’s total 15,738,333 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) together control 40% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
GILEAD SCIENCES, INC. 29% 4,505,391 0% 7.9% $153,228,348
VANGUARD GROUP INC 3.6% 572,898 +14% 0% $19,484,260
FRANKLIN RESOURCES INC 1.3% 210,528 0% 0% $7,160,057
BlackRock, Inc. 1.2% 192,296 +13% 0% $6,539,986
GEODE CAPITAL MANAGEMENT, LLC 0.83% 131,307 +0.93% 0% $4,467,714
MARSHALL WACE, LLP 0.82% 129,075 +51% 0% $4,389,840
Patient Square Capital LP 0.81% 127,000 -6.1% 0.92% $4,319,270
JANE STREET GROUP, LLC 0.34% 53,702 +59% 0% $1,826,405
STATE STREET CORP 0.34% 52,989 +18% 0% $1,802,156
JPMORGAN CHASE & CO 0.31% 48,159 +687886% 0% $1,637,888
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.24% 37,812 0% $1,285,986
Palumbo Wealth Management LLC 0.24% 37,305 +7.2% 0.31% $1,268,744
GOLDMAN SACHS GROUP INC 0.22% 34,794 +97% 0% $1,183,344
Ellsworth Advisors, LLC 0.19% 29,735 -0.72% 0.18% $889,374
Informed Momentum Co LLC 0.19% 29,523 +1.6% 0.11% $1,004,077
FEDERATED HERMES, INC. 0.16% 25,394 0% 0% $863,650
BARCLAYS PLC 0.16% 24,741 +525% 0% $841,442
MORGAN STANLEY 0.14% 22,534 +539% 0% $766,381
Connor, Clark & Lunn Investment Management Ltd. 0.13% 20,802 +86% 0% $707,476
SEI INVESTMENTS CO 0.11% 17,745 0% $603,507
OMERS ADMINISTRATION Corp 0.1% 15,598 0% $530,488
Hudson Bay Capital Management LP 0.1% 15,050 0% $511,851
GSA CAPITAL PARTNERS LLP 0.08% 12,699 +2.2% 0.04% $432,000
ACADIAN ASSET MANAGEMENT LLC 0.08% 12,446 -47% 0% $422,000
UBS Group AG 0.06% 9,779 -38% 0% $332,583

Institutional Holders of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 6,388,221 $217,142,264 -$5,177,941 $34.01 36
2025 Q3 12,244,439 $313,500,808 +$233,088,276 $25.60 56
2025 Q2 3,148,479 $57,049,319 +$415,033 $18.12 33
2025 Q1 3,175,639 $30,358,304 -$551,384 $9.56 36
2024 Q4 3,185,761 $50,270,587 -$3,179,725 $15.78 35
2024 Q3 1,026,987 $15,540,749 -$2,242,995 $15.14 30
2024 Q2 1,175,256 $16,110,171 +$7,242,756 $13.72 27
2024 Q1 647,283 $8,609,474 +$8,609,474 $13.30 24