ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2024 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.001 per shares (the "Shares")
Symbol
ASMB on Nasdaq
Shares outstanding
15,738,333
Price per share
$26.80
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
13,650,452
Total reported value
$464,172,637
% of total 13F portfolios
0%
Share change
+1,211,715
Value change
+$45,981,788
Number of holders
68
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Commodore Capital LP 9.9% $29,281,576 1,615,981 Commodore Capital LP 08 Aug 2025
RA CAPITAL MANAGEMENT, L.P. 9.5% $28,392,908 1,530,615 RA Capital Management, L.P. 11 Aug 2025
JANUS HENDERSON GROUP PLC 8.2% $44,444,160 1,341,508 JANUS HENDERSON GROUP PLC 28 Nov 2025
Farallon Capital Partners, L.P. 7.8% +7.1% $38,963,707 +$2,763,919 1,227,590 +7.6% Dapice Joshua J. 31 Dec 2025
Schornstein Alexander 3.5% -65% $10,082,352 -$3,424,144 543,523 -25% Alexander Schornstein 11 Aug 2025
ARMISTICE CAPITAL, LLC 10% $5,252,553 289,876 Armistice Capital, LLC 30 Jun 2025

As of 31 Dec 2025, 68 institutional investors reported holding 13,650,452 shares of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB). This represents 87% of the company’s total 15,738,333 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) together control 82% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
GILEAD SCIENCES, INC. 29% 4,505,391 0% 7.9% $153,228,348
FARALLON CAPITAL MANAGEMENT LLC 7.8% 1,227,590 0% 0.24% $41,750,336
RA CAPITAL MANAGEMENT, L.P. 6.5% 1,020,410 0% 0.36% $34,704,144
Commodore Capital LP 6.4% 1,000,000 0% 2.3% $34,010,000
JANUS HENDERSON GROUP PLC 5.3% 837,925 +11% 0.01% $28,539,726
Paradigm Biocapital Advisors LP 4.2% 665,251 0.61% $22,625,187
Point72 Asset Management, L.P. 3.8% 600,609 +103% 0.03% $20,426,712
VANGUARD GROUP INC 3.6% 572,898 +14% 0% $19,484,260
Blackstone Inc. 2% 318,754 -29% 0.05% $10,840,824
Parkman Healthcare Partners LLC 1.6% 249,357 -0.65% 0.81% $8,480,632
FRANKLIN RESOURCES INC 1.3% 210,528 0% 0% $7,160,057
BlackRock, Inc. 1.2% 192,296 +13% 0% $6,539,986
B Group, Inc. 1.1% 175,706 0% 4.4% $5,975,761
ADAGE CAPITAL PARTNERS GP, L.L.C. 1% 161,000 0.01% $5,475,610
Eversept Partners, LP 1% 159,676 0.3% $5,430,581
STEMPOINT CAPITAL LP 1% 156,728 +137% 0.91% $5,330,319
GEODE CAPITAL MANAGEMENT, LLC 0.83% 131,307 +0.93% 0% $4,467,714
MARSHALL WACE, LLP 0.82% 129,075 +51% 0% $4,389,840
Patient Square Capital LP 0.81% 127,000 -6.1% 0.92% $4,319,270
Caption Management, LLC 0.68% 106,591 0.16% $3,625,160
MILLENNIUM MANAGEMENT LLC 0.62% 98,221 +355% 0% $3,340,496
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.51% 80,394 -39% 0% $2,734,200
SUPERSTRING CAPITAL MANAGEMENT LP 0.41% 65,273 1.2% $2,219,935
Schonfeld Strategic Advisors LLC 0.34% 54,235 -56% 0.01% $1,844,529
JANE STREET GROUP, LLC 0.34% 53,702 +59% 0% $1,826,405

Institutional Holders of ASSEMBLY BIOSCIENCES, INC. - Common Stock, par value $0.001 per shares (the "Shares") (ASMB) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 13,650,452 $464,172,637 +$45,981,788 $34.01 68
2025 Q3 12,244,439 $313,500,808 +$233,088,276 $25.60 56
2025 Q2 3,148,479 $57,049,319 +$415,033 $18.12 33
2025 Q1 3,175,639 $30,358,304 -$551,384 $9.56 36
2024 Q4 3,185,761 $50,270,587 -$3,179,725 $15.78 35
2024 Q3 1,026,987 $15,540,749 -$2,242,995 $15.14 30
2024 Q2 1,175,256 $16,110,171 +$7,242,756 $13.72 27
2024 Q1 647,283 $8,609,474 +$8,609,474 $13.30 24