Latest Period
Q4 2025
Security Snapshot
ARGENX SE - ADR (ARGX) Institutional Ownership
CUSIP: 04016X101
13F Institutional Holders and Ownership History from Q2 2017 to Q1 2026
Institutions Reporting
505
Shares (Excl. Options)
29,738,049
Price
$840.95
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- Type / Class
- Equity / ADR
- Symbol
- ARGX on Nasdaq
- Shares outstanding
- 60,783,333
- Price per share
- $730.25
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 29,738,049
- Total reported value
- $24,998,247,774
- % of total 13F portfolios
- 0.02%
- Share change
- -808,317
- Value change
- -$642,173,091
- Number of holders
- 505
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- ARGX - ARGENX SE - ADR is tracked under CUSIP 04016X101.
- 505 institutions reported positions in Q4 2025.
- 2 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 505 to 191 between Q4 2025 and Q1 2026.
- Reported value moved from $24,998,247,774 to $1,255,702,703.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 505 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 04016X101?
CUSIP 04016X101 identifies ARGX - ARGENX SE - ADR in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 04016X101:
Significant Owners of ARGENX SE - ADR (ARGX) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD/ | 6% | -28% | $2,689,881,320 | -$985,796,144 | 3,647,000 | -27% | T. Rowe Price Associates, Inc. | 30 Sep 2025 |
| Artisan Partners Limited Partnership | 3.8% | $1,316,438,506 | 2,349,776 | Artisan Partners Asset Management Inc. | 30 Jun 2025 |
As of 31 Dec 2025, 505 institutional investors reported holding 29,738,049 shares of ARGENX SE - ADR (ARGX). This represents 49% of the company’s total 60,783,333 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of ARGENX SE - ADR (ARGX) together control 39% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 9.2% | 5,592,319 | -1.8% | 0.24% | $4,702,860,205 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5.5% | 3,362,324 | -7.6% | 0.3% | $2,827,547,000 |
| JANUS HENDERSON GROUP PLC | 4% | 2,458,164 | -4.5% | 0.92% | $2,057,856,370 |
| Capital World Investors | 3.2% | 1,916,234 | -2.2% | 0.22% | $1,611,433,480 |
| Artisan Partners Limited Partnership | 2.9% | 1,756,942 | -20% | 2.3% | $1,477,500,737 |
| Avoro Capital Advisors LLC | 1.6% | 990,000 | 0% | 8.2% | $832,540,500 |
| BlackRock, Inc. | 1.2% | 735,598 | +40% | 0.01% | $618,601,356 |
| WELLINGTON MANAGEMENT GROUP LLP | 1.1% | 679,236 | -7% | 0.1% | $571,203,514 |
| RTW INVESTMENTS, LP | 1.1% | 673,497 | 0% | 5.7% | $566,377,302 |
| MORGAN STANLEY | 0.85% | 518,851 | +19% | 0.03% | $436,329,657 |
| Clearbridge Investments, LLC | 0.85% | 513,764 | -32% | 0.35% | $432,050,063 |
| Bellevue Group AG | 0.76% | 461,854 | -15% | 7.4% | $388,396,121 |
| Invesco Ltd. | 0.69% | 416,408 | +390% | 0.05% | $350,178,308 |
| ALLIANCEBERNSTEIN L.P. | 0.68% | 414,182 | +389% | 0.11% | $348,306,353 |
| BANK OF AMERICA CORP /DE/ | 0.66% | 400,776 | +17% | 0.02% | $337,032,576 |
| SANDS CAPITAL MANAGEMENT, LLC | 0.59% | 356,870 | +2047% | 0.91% | $300,109,826 |
| CITADEL ADVISORS LLC | 0.58% | 350,851 | -51% | 0.2% | $295,048,149 |
| SEI INVESTMENTS CO | 0.54% | 330,506 | +5.8% | 0.27% | $277,936,826 |
| TWO SIGMA INVESTMENTS, LP | 0.43% | 258,556 | -12% | 0.32% | $217,432,668 |
| FRANKLIN RESOURCES INC | 0.39% | 237,701 | -8% | 0.05% | $199,895,051 |
| JENNISON ASSOCIATES LLC | 0.38% | 229,761 | -4.4% | 0.12% | $193,217,916 |
| Fiera Capital Corp | 0.37% | 225,971 | +27% | 0.6% | $190,030,312 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 0.37% | 223,666 | 0.52% | $188,070,728 | |
| AMERICAN CENTURY COMPANIES INC | 0.36% | 221,048 | -3.8% | 0.09% | $185,895,645 |
| LORD, ABBETT & CO. LLC | 0.34% | 203,864 | +3.5% | 0.53% | $171,439,000 |
Institutional Holders of ARGENX SE - ADR (ARGX) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 1,716,376 | $1,255,702,703 | -$19,460,913 | $730.25 | 191 |
| 2025 Q4 | 29,738,049 | $24,998,247,774 | -$642,173,091 | $840.95 | 505 |
| 2025 Q3 | 30,517,541 | $22,513,715,603 | -$1,073,799,877 | $737.56 | 463 |
| 2025 Q2 | 32,113,379 | $17,700,251,639 | -$650,880,957 | $551.22 | 432 |
| 2025 Q1 | 33,350,566 | $19,728,647,418 | -$538,199,538 | $591.86 | 440 |
| 2024 Q4 | 34,127,043 | $20,989,465,522 | -$514,339,139 | $615.00 | 392 |
| 2024 Q3 | 35,023,889 | $18,983,773,082 | +$318,558,493 | $542.08 | 353 |
| 2024 Q2 | 34,272,091 | $14,739,068,000 | +$209,398,089 | $430.04 | 333 |
| 2024 Q1 | 33,972,829 | $13,375,733,075 | +$491,825,471 | $393.72 | 323 |
| 2023 Q4 | 32,743,580 | $12,457,326,565 | -$54,572,297 | $380.43 | 344 |
| 2023 Q3 | 32,304,467 | $15,882,569,669 | +$743,873,334 | $491.63 | 339 |
| 2023 Q2 | 30,837,175 | $12,017,706,842 | -$124,589,442 | $389.73 | 284 |
| 2023 Q1 | 31,161,539 | $11,606,411,682 | +$212,961,249 | $372.58 | 268 |
| 2022 Q4 | 30,636,859 | $11,606,887,640 | -$327,489,209 | $378.83 | 269 |
| 2022 Q3 | 31,719,850 | $11,203,694,460 | -$1,130,342,709 | $353.05 | 247 |
| 2022 Q2 | 32,849,679 | $12,441,524,780 | +$297,990,141 | $378.88 | 226 |
| 2022 Q1 | 32,214,227 | $10,157,335,912 | +$1,037,726,968 | $315.31 | 196 |
| 2021 Q4 | 28,919,142 | $10,126,721,772 | +$177,117,824 | $350.19 | 203 |
| 2021 Q3 | 28,383,120 | $8,571,126,445 | -$97,752,555 | $302.00 | 178 |
| 2021 Q2 | 28,455,441 | $8,567,827,463 | +$1,980,236 | $301.07 | 173 |
| 2021 Q1 | 28,512,399 | $7,852,287,235 | +$830,872,986 | $275.39 | 185 |
| 2020 Q4 | 25,489,136 | $7,496,328,068 | -$41,742,172 | $294.09 | 170 |
| 2020 Q3 | 25,619,531 | $6,725,637,706 | -$279,942,268 | $262.52 | 154 |
| 2020 Q2 | 26,726,537 | $6,038,628,842 | +$787,556,149 | $225.23 | 162 |
| 2020 Q1 | 23,348,647 | $3,076,234,326 | -$61,977,095 | $131.73 | 139 |
| 2019 Q4 | 23,704,346 | $3,805,799,945 | +$211,376,338 | $160.52 | 146 |
| 2019 Q3 | 22,370,016 | $2,548,680,181 | -$6,180,324 | $113.96 | 129 |
| 2019 Q2 | 22,382,688 | $3,168,153,526 | +$202,152,598 | $141.58 | 132 |
| 2019 Q1 | 21,861,856 | $2,728,838,981 | +$198,069,924 | $124.84 | 129 |
| 2018 Q4 | 20,499,548 | $1,969,933,884 | +$12,993,447 | $96.07 | 108 |
| 2018 Q3 | 20,684,670 | $1,568,631,975 | +$198,929,711 | $75.84 | 105 |
| 2018 Q2 | 18,031,387 | $1,494,404,458 | +$85,594,520 | $82.86 | 82 |
| 2018 Q1 | 16,999,982 | $1,367,312,465 | +$220,516,340 | $80.44 | 83 |
| 2017 Q4 | 14,513,752 | $916,370,452 | +$485,289,724 | $63.14 | 64 |
| 2017 Q3 | 6,945,598 | $155,726,000 | +$18,796,428 | $22.60 | 31 |
| 2017 Q2 | 6,115,317 | $129,239,000 | +$129,239,000 | $21.21 | 31 |