Security key
03969K108
CUSIP: 03969K108
Security key
03969K108
Report period
Q4 2025
Institutions
280
Top holders
10
Broader feeds
Reporting periods
Recent filing periods:
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Frazier Life Sciences VIII, L.P. |
13D/G
3/4/5
|
Patrick J. Heron · 10%+ Owner |
7.5%
|
8,943,712
|
$130,399,321 | $0 | 18 Aug 2025 | |
| Rubric Capital Management LP |
13D/G
13F
|
Company |
6.8%
|
8,271,577
|
$239,875,733 | $0 | 31 Dec 2025 | |
| Polar Capital Holdings Plc |
13F
13D/G
|
Company |
4.2%
from 13D/G
|
5,298,754
|
$99,881,513 | — | 30 Sep 2025 | |
| Halley E. Gilbert |
3/4/5
|
Director |
0.02%
|
22,123
|
$609,468 | -$455,442 | 20 Nov 2025 | |
| Neha Krishnamohan |
3/4/5
|
Director |
0.02%
|
22,123
|
$517,014 | -$939,494 | 13 Nov 2025 | |
| JENNISON ASSOCIATES LLC |
13F
|
Company |
9.9%
|
12,254,119
|
$230,990,144 | — | 30 Sep 2025 | |
| SUVRETTA CAPITAL MANAGEMENT, LLC |
13F
|
Company |
8.5%
|
10,478,000
|
$197,510,300 | — | 30 Sep 2025 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
8%
|
9,874,511
|
$186,134,532 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
6.9%
|
8,573,995
|
$161,619,806 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
5.8%
|
7,146,090
|
$134,703,797 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
3.8%
|
4,641,315
|
$87,488,788 | — | 30 Sep 2025 | |
| GILDER GAGNON HOWE & CO LLC |
13F
|
Company |
3.6%
|
4,429,108
|
$83,488,686 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
3.5%
|
4,276,394
|
$80,610,030 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
2.4%
|
2,948,438
|
$55,578,057 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
2.1%
|
2,606,465
|
$49,139,527 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
1.9%
|
2,398,031
|
$45,178,904 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
1.9%
|
2,311,019
|
$43,562,708 | — | 30 Sep 2025 | |
| Pivotal bioVenture Partners Investment Advisor LLC |
13F
|
Company |
1.7%
|
2,120,508
|
$39,971,576 | — | 30 Sep 2025 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
1.7%
|
2,118,713
|
$39,937,740 | — | 30 Sep 2025 | |
| Perpetual Ltd |
13F
|
Company |
1.6%
|
2,024,606
|
$38,163,823 | — | 30 Sep 2025 | |
| Ensign Peak Advisors, Inc |
13F
|
Company |
1.6%
|
1,993,055
|
$37,569,087 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1.5%
|
1,804,988
|
$34,024,024 | — | 30 Sep 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
1.3%
|
1,662,470
|
$31,337,590 | — | 30 Sep 2025 | |
| Nuveen, LLC |
13F
|
Company |
1.1%
|
1,370,356
|
$25,831,211 | — | 30 Sep 2025 | |
| GW&K Investment Management, LLC |
13F
|
Company |
0.95%
|
1,172,041
|
$22,093,000 | — | 30 Sep 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.89%
|
1,097,004
|
$20,678,525 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.81%
|
999,434
|
$18,839,331 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.76%
|
940,202
|
$17,722,808 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.72%
|
889,285
|
$16,763,022 | — | 30 Sep 2025 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.68%
|
833,490
|
$15,711,286 | — | 30 Sep 2025 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.66%
|
814,567
|
$15,354,588 | — | 30 Sep 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.63%
|
778,044
|
$14,666,129 | — | 30 Sep 2025 | |
| Cormorant Asset Management, LP |
13F
|
Company |
0.63%
|
775,000
|
$14,608,750 | — | 30 Sep 2025 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
0.62%
|
759,573
|
$14,317,951 | — | 30 Sep 2025 | |
| Aberdeen Group plc |
13F
|
Company |
0.55%
|
675,034
|
$12,724,391 | — | 30 Sep 2025 | |
| JUPITER ASSET MANAGEMENT LTD |
13F
|
Company |
0.53%
|
659,331
|
$12,428,390 | — | 30 Sep 2025 | |
| FISHMAN JAY A LTD/MI |
13F
|
Company |
0.46%
|
565,650
|
$10,662,503 | — | 30 Sep 2025 | |
| Tejara Capital Ltd |
13F
|
Company |
0.42%
|
520,503
|
$9,811,482 | — | 30 Sep 2025 | |
| MYDA Advisors LLC |
13F
|
Company |
0.38%
|
470,000
|
$8,859,500 | — | 30 Sep 2025 | |
| AQR CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.36%
|
441,315
|
$8,318,787 | — | 30 Sep 2025 | |
| STEMPOINT CAPITAL LP |
13F
|
Company |
0.33%
|
411,893
|
$7,764,183 | — | 30 Sep 2025 | |
| DEUTSCHE BANK AG\ |
13F
|
Company |
0.31%
|
377,528
|
$7,116,403 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.29%
|
360,770
|
$6,800,515 | — | 30 Sep 2025 | |
| PFM Health Sciences, LP |
13F
|
Company |
0.29%
|
360,460
|
$6,794,671 | — | 30 Sep 2025 | |
| J. Goldman & Co LP |
13F
|
Company |
0.29%
|
353,644
|
$6,666,189 | — | 30 Sep 2025 | |
| Jump Financial, LLC |
13F
|
Company |
0.28%
|
350,485
|
$6,606,642 | — | 30 Sep 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.26%
|
325,968
|
$6,144,497 | — | 30 Sep 2025 | |
| Simplify Asset Management Inc. |
13F
|
Company |
0.26%
|
317,997
|
$5,994,243 | — | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.25%
|
314,619
|
$5,930,568 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.25%
|
310,620
|
$5,855,188 | — | 30 Sep 2025 |
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).