Aprea Therapeutics, Inc. - Common Stock (APRE) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2023 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
APRE on Nasdaq
Shares outstanding
6,887,242
Price per share
$0.92
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
1,618,851
Total reported value
$2,387,744
% of total 13F portfolios
0%
Share change
-198,357
Value change
-$296,033
Number of holders
23
Price from insider filings
$0.92
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Aprea Therapeutics, Inc. - Common Stock (APRE) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
LYTTON LAURENCE W 9.9% $913,662 681,837 LYTTON LAURENCE W 13 Nov 2025
Nantahala Capital Management, LLC 7.3% $720,160 411,520 Nantahala Capital Management, LLC 30 Sep 2024
Stonepine Capital Management, LLC 4.3% -16% $418,978 -$82,213 239,416 -16% Stonepine Capital Management, LLC 31 Mar 2025
Sio Capital Management, LLC 1.9% -62% $165,529 -$246,540 112,223 -60% Sio Capital Management, LLC 30 Sep 2025

As of 30 Sep 2025, 23 institutional investors reported holding 1,618,851 shares of Aprea Therapeutics, Inc. - Common Stock (APRE). This represents 24% of the company’s total 6,887,242 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Aprea Therapeutics, Inc. - Common Stock (APRE) together control 24% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
AIGH Capital Management LLC 7.8% 539,300 0% 0.28% $795,467
SPHERA FUNDS MANAGEMENT LTD. 3.9% 270,000 0% 0.09% $398,250
Nantahala Capital Management, LLC 3% 205,760 0% 0.02% $303,496
VANGUARD GROUP INC 2.3% 158,238 -9% 0% $233,401
DAFNA Capital Management LLC 2% 137,174 0% 0.05% $202,332
Sio Capital Management, LLC 1.6% 112,223 -60% 0.04% $165,529
MORGAN STANLEY 0.96% 65,808 +3.9% 0% $97,067
GEODE CAPITAL MANAGEMENT, LLC 0.65% 44,616 +3.4% 0% $65,818
BNP PARIBAS FINANCIAL MARKETS 0.25% 17,132 0% 0% $25,270
LPL Financial LLC 0.23% 16,052 -5.9% 0% $23,677
HighTower Advisors, LLC 0.2% 13,864 0% 0% $20,449
HRT FINANCIAL LP 0.18% 12,264 0% $18,000
LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 0.15% 10,496 -56% 0% $15,481
BlackRock, Inc. 0.12% 8,504 0% 0% $12,543
BANK OF AMERICA CORP /DE/ 0.07% 4,861 +0.1% 0% $7,170
MB, LEVIS & ASSOCIATES, LLC 0.01% 806 0% 0% $1,189
GROUP ONE TRADING LLC 0.01% 577 0% 0% $851
Tower Research Capital LLC (TRC) 0.01% 568 -81% 0% $838
OSAIC HOLDINGS, INC. 0.01% 400 0% 0% $609
WealthCollab, LLC 0% 158 0% 0% $234
SBI Securities Co., Ltd. 0% 42 +5% 0% $62
CITIGROUP INC 0% 5 0% $7
UBS Group AG 0% 3 -62% 0% $4
DIMENSIONAL FUND ADVISORS LP 0% 0 -100% $0
FMR LLC 0% 0 -100% $0

Institutional Holders of Aprea Therapeutics, Inc. - Common Stock (APRE) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 0 $0 -$1,189 $0.92 0
2025 Q3 1,618,851 $2,387,744 -$296,033 $1.48 23
2025 Q2 1,815,508 $3,072,270 -$77,601 $1.69 23
2025 Q1 1,847,462 $3,768,839 -$165,845 $2.04 25
2024 Q4 2,077,381 $6,829,282 +$211,103 $3.29 26
2024 Q3 2,000,189 $5,500,414 -$431,314 $2.75 21
2024 Q2 2,083,045 $8,477,419 +$1,866,030 $4.07 27
2024 Q1 1,624,394 $10,764,195 +$4,966,764 $6.69 22
2023 Q4 926,780 $4,355,977 +$26,645 $4.70 19
2023 Q3 876,935 $3,660,270 -$19,509 $4.17 19
2023 Q2 881,553 $2,776,892 +$105,033 $3.15 17
2023 Q1 848,237 $3,769,266 +$3,769,266 $4.44 15