13F reference period
Q2 2026
CUSIP: 008064206
13F reference period
Q2 2026
Institutions Reporting
150
Shares (Excl. Options)
Price
$22.22
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 150 institutions filings for Q2 2026.
Security key
008064206
13F reference period
Q2 2026
13F holders
150
13D/G owners
14
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 008064206:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Fairmount Funds Management LLC | 20% | 0% | $354,973,334 | +$93,745,067 | 14,069,494 | +36% | Fairmount Funds Management LLC | 05 Jun 2026 |
| Janus Henderson Group Ltd. | 11% | +72% | $139,393,136 | +$70,384,550 | 6,273,262 | +102% | JANUS HENDERSON GROUP Ltd. | 30 Jun 2026 |
| Venrock Healthcare Capital Partners III, L.P. | 8.3% | -16% | $107,794,664 | +$617,355 | 5,145,330 | +0.58% | Venrock Healthcare Capital Partners III, L.P. | 30 Jun 2026 |
| FMR LLC | 15% | $40,965,976 | 4,735,951 | FMR LLC | 30 May 2025 | |||
| FRANKLIN TEMPLETON INC | 6% | $53,491,285 | 3,807,236 | Franklin Templeton, Inc. | 30 Sep 2026 | |||
| BlackRock, Inc. | 5.2% | +10% | $46,692,047 | +$14,435,935 | 3,323,301 | +45% | BlackRock, Inc. | 30 Sep 2026 |
| RA CAPITAL MANAGEMENT, L.P. | 7% | +72% | $27,758,364 | +$16,318,579 | 3,214,969 | +143% | RA Capital Management, L.P. | 08 Oct 2025 |
| Paradigm Biocapital Advisors LP | 5.1% | $69,032,630 | 3,106,793 | Paradigm BioCapital Advisors LP | 10 Jul 2026 | |||
| Bellevue Group AG | 5% | -26% | $64,065,016 | -$5,931,092 | 3,057,996 | -8.5% | Bellevue Group AG | 30 Jun 2026 |
| VANGUARD GROUP INC | 4.2% | -23% | $32,337,685 | +$4,446,695 | 2,095,767 | +16% | The Vanguard Group | 31 Dec 2025 |
| Frazier Life Sciences Public Fund, L.P. | 4.2% | 0% | $11,949,495 | +$379,228 | 1,384,646 | +3.3% | Frazier Life Sciences Public Fund, L.P. | 30 Sep 2025 |
| Sofinnova Venture Partners X, L.P. | 0.3% | $1,617,308 | 107,391 | Sofinnova Venture Partners X, L.P. ("SVP X") | 28 Apr 2025 | |||
| TCG Crossover GP I, LLC | 0.2% | $649,193 | 64,023 | TCG Crossover GP I, LLC | 28 Apr 2025 | |||
| Atlas Venture Fund XII, L.P. | 0.2% | $521,257 | 51,406 | Atlas Venture Associates XII, L.P. | 28 Apr 2025 |
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 14% | 9,126,877 | +29% | 0.01% | $202,799,207 |
| Jupiter Topco LLC | 9.9% | 6,273,262 | 0% | 0.06% | $139,369,006 |
| Fairmount Funds Management LLC | 7.2% | 4,553,494 | 0% | 6.7% | $101,178,637 |
| RA CAPITAL MANAGEMENT, L.P. | 5.8% | 3,671,083 | 0% | 0.71% | $81,571,464 |
| Venrock Adviser, LLC | 5.1% | 3,220,364 | 0% | 2.2% | $71,556,488 |
| Bellevue Group AG | 4.8% | 3,057,996 | -13% | 1.4% | $67,948,671 |
| Paradigm Biocapital Advisors LP | 4.5% | 2,857,405 | 1.2% | $63,491,539 | |
| BlackRock, Inc. | 4.4% | 2,801,451 | +21% | 0% | $62,248,241 |
| FRANKLIN RESOURCES INC | 4.4% | 2,792,080 | 0.01% | $62,040,028 | |
| STATE STREET CORP | 3.7% | 2,335,285 | +256% | 0% | $51,890,033 |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.5% | 2,244,773 | +25% | 0% | $49,878,856 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3% | 1,910,812 | 0.06% | $42,458,243 | |
| Polar Capital Holdings Plc | 2.9% | 1,846,982 | 0.12% | $41,039,940 | |
| Avidity Partners Management LP | 2.7% | 1,700,708 | +21% | 6.1% | $37,789,732 |
| Remedium Capital Partners, LLC | 2.5% | 1,577,750 | 0% | 7.8% | $35,057,605 |
| Soleus Capital Management, L.P. | 2.4% | 1,550,690 | +95% | 1.2% | $34,456,332 |
| JPMORGAN CHASE & CO | 2.3% | 1,475,079 | +9199% | 0% | $32,613,997 |
| BAKER BROS. ADVISORS LP | 1.9% | 1,230,426 | -25% | 0.14% | $27,340,066 |
| Logos Global Management LP | 1.8% | 1,125,000 | +181% | 1.1% | $24,997,500 |
| Versant Venture Management, LLC | 1.6% | 991,783 | -35% | 14% | $22,037,418 |
| ACORN CAPITAL ADVISORS, LLC | 1.6% | 986,760 | +25% | 6% | $21,925,807 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 985,178 | +20% | 0% | $21,896,658 |
| CITADEL ADVISORS LLC | 1.5% | 929,407 | +577% | 0.01% | $20,651,423 |
| Foresite Capital Management VI LLC | 1.4% | 886,667 | +177% | 3.1% | $19,701,741 |
| Balyasny Asset Management L.P. | 1.4% | 878,726 | +118% | 0.04% | $19,525,292 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 31,972 | $449,208 | -$196,331 | $14.05 | 17 |
| 2026 Q2 | 72,902,699 | $1,619,316,966 | +$459,525,093 | $22.22 | 150 |
| 2026 Q1 | 49,846,615 | $700,290,229 | +$35,560,462 | $14.05 | 118 |
| 2025 Q4 | 47,075,378 | $726,260,386 | +$242,240,917 | $15.43 | 102 |
| 2025 Q3 | 31,617,300 | $272,859,518 | +$407,366 | $8.63 | 74 |
| 2025 Q2 | 31,531,484 | $315,000,764 | +$314,968,047 | $9.99 | 70 |