Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (SYRE)

CUSIP: 00773J202

Q3 2023 13F Holders as of 30 Sep 2023

Type / Class
Equity / Common Stock, $0.0001 Par Value Per Share
Shares outstanding
86,389,920
Total 13F shares
3,257,983
Share change
+3,257,983
Total reported value
$39,909,852
Put/Call ratio
7.1%
Price per share
$12.25
Number of holders
27
Value change
+$39,909,852
Number of buys
27

Quarterly Holders Quick Answers

What is CUSIP 00773J202?
CUSIP 00773J202 identifies SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share in SEC institutional holdings data.

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Top shareholders of SYRE - Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
Anthony G. Quinn
3/4/5
President & CEO, Director
class O/S missing
816,835
$579,952 16 Mar 2022
Marcio Souza
3/4/5
Director
class O/S missing
90,000
$63,900 25 Aug 2022
Jonathan Alspaugh
3/4/5
President and CFO
class O/S missing
19,787,969
22 Jun 2023
Alison Frances Lawton
3/4/5
Director
class O/S missing
1,950,000
22 Jun 2023
Hunter C. Smith
3/4/5
Director
class O/S missing
1,950,000
22 Jun 2023
Ivana Magovcevic-Liebisch
3/4/5
Director
class O/S missing
1,950,000
22 Jun 2023
Russell J. Cox
3/4/5
Director
class O/S missing
1,950,000
22 Jun 2023
Jeff Marc Goldberg
3/4/5
President and CEO, Director
class O/S missing
1,884,838
29 Nov 2022
Linda L. Neuman
3/4/5
Chief Medical Officer
class O/S missing
550,000
23 Feb 2023
James Paul Kastenmayer
3/4/5
General Counsel
class O/S missing
500,000
23 Feb 2023
Jr. Michael Conick Hanley
3/4/5
Chief Business Officer
class O/S missing
500,000
23 Feb 2023
Leslie Sloan
3/4/5
Chief Operating Officer
class O/S missing
130,000
23 Aug 2022
Armen Shanafelt
3/4/5
Director
class O/S missing
43,000
07 Jun 2022
Bryan Lawlis V
3/4/5
Director
class O/S missing
43,000
07 Jun 2022
Sandesh Mahatme
3/4/5
Director
class O/S missing
43,000
07 Jun 2022
BAKER BROS. ADVISORS LP
3/4/5
Director
class O/S missing
40,000
08 Jun 2021
Steven Weber
3/4/5
VP, Controller&Princ Acctg Off
class O/S missing
30,000
17 Feb 2022

Institutional Holders of Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (SYRE) as of Q3 2023

As of 30 Sep 2023, Spyre Therapeutics, Inc. - Common Stock, $0.0001 Par Value Per Share (SYRE) was held by 27 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 3,257,983 shares. The largest 10 holders included Driehaus Capital Management LLC, Fairmount Funds Management LLC, Polar Capital Holdings Plc, WELLINGTON MANAGEMENT GROUP LLP, Affinity Asset Advisors, LLC, Logos Global Management LP, EcoR1 Capital, LLC, SUVRETTA CAPITAL MANAGEMENT, LLC, Rock Springs Capital Management LP, and COMMODORE CAPITAL LP. This page lists 27 institutional shareholders reporting positions in this security for the Q3 2023 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q3 2023 vs Q4 2025 Across Filers

Q4 2025 holders
152
Q3 2023 holders
27
Holder diff
-125
Investor Q4 2025 Shares Q3 2023 Shares Share Diff Share Chg % Q4 2025 Value $ Q3 2023 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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