AERIE PHARMACEUTICALS INC - COM (AERI)

Q4 2021 13F Holders as of 12/31/2021

Type / Class: Equity / COM
Number of holders: 127
Total Shares: 47.3M
Shares change: +927K
Total reported value, excl. options: $332M
Value change: -$7.11M
Put/Call ratio: 0.21
Number of buys: 62
Number of sells: -74
Price: $7.02

Investor	Weight %	Change %	Value $	* Price $	Shares	Share Change	Activity	Report Period
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.69%	+0.25%	$33M	7.02	4.7M	+1.72M	+57.7%	12/31/2021
MORGAN STANLEY	0%	+0%	$28.3M	7.02	4.03M	+1.81M	+81.6%	12/31/2021
BlackRock Inc.	0%	0%	$23.8M	7.02	3.39M	-37.7K	-1.1%	12/31/2021
VANGUARD GROUP INC	0%	0%	$23.7M	7.02	3.38M	-995K	-22.7%	12/31/2021
Jefferies Group LLC	0.31%	+0.31%	$16.7M	7.02	2.38M	+2.38M	NEW	12/31/2021
BANK OF AMERICA CORP /DE/	0%	0%	$16.5M	7.02	2.35M	-274K	-10.4%	12/31/2021
AMERIPRISE FINANCIAL INC	0%	+0%	$14.2M	7.02	2.03M	+407K	+25.1%	12/31/2021
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.03%	-0.02%	$12.7M	7.02	1.81M	-1.07M	-37.2%	12/31/2021
SCHRODER INVESTMENT MANAGEMENT GROUP	0.01%	+0%	$9.5M	7.02	1.35M	+20K	+1.5%	12/31/2021
Granahan Investment Management, LLC	0.18%	-0.02%	$8.7M	7.02	1.24M	-155K	-11.1%	12/31/2021
RICE HALL JAMES & ASSOCIATES, LLC	0.3%	-0.01%	$8.45M	7.02	1.2M	-29K	-2.35%	12/31/2021
C WorldWide Group Holding A/S	0.08%		$8.12M	7.02	1.16M			12/31/2021
PFM Health Sciences, LP	0.27%	-0.27%	$7.64M	7.02	1.09M	-1.09M	-50.1%	12/31/2021
STATE STREET CORP	0%	+0%	$7.6M	7.02	1.08M	+122K	+12.7%	12/31/2021
CITIGROUP INC	0.01%	0%	$7.58M	7.02	1.08M	-175K	-14%	12/31/2021
MILLENNIUM MANAGEMENT LLC	0.01%	+0.01%	$7.14M	7.02	1.02M	+890K	+696.2%	12/31/2021
JACOBS LEVY EQUITY MANAGEMENT, INC	0.05%	+0.02%	$7.12M	7.02	1.01M	+410K	+67.8%	12/31/2021
GEODE CAPITAL MANAGEMENT, LLC	0%	+0%	$5.88M	7.02	838K	+185K	+28.3%	12/31/2021
LEVIN CAPITAL STRATEGIES, L.P.	0.54%	-0.37%	$5.74M	7.02	817K	-556K	-40.5%	12/31/2021
Rhenman & Partners Asset Management AB	0.36%		$5.38M	7.17	750K			12/31/2021
PINNACLE ASSOCIATES LTD	0.09%	+0.01%	$5.2M	7.02	740K	+50K	+7.24%	12/31/2021
Novo Holdings A/S	0.18%		$3.9M	7.02	555K			12/31/2021
FRED ALGER MANAGEMENT, LLC	0.01%	-0.01%	$3.69M	7.02	525K	-559K	-51.5%	12/31/2021
Granite Investment Partners, LLC	0.1%	+0.01%	$3.35M	7.02	477K	+66.7K	+16.2%	12/31/2021
NORTHERN TRUST CORP	0%	0%	$3.24M	7.02	462K	-1.05K	-0.23%	12/31/2021
Cubist Systematic Strategies, LLC	0.03%	+0.03%	$3.2M	7.02	456K	+456K	NEW	12/31/2021
RENAISSANCE TECHNOLOGIES LLC	0%	+0%	$2.7M	7.02	384K	+62.6K	+19.5%	12/31/2021
Nuveen Asset Management, LLC	0%	+0%	$2.67M	7.02	380K	+6.41K	+1.71%	12/31/2021
Walleye Capital LLC	0.1%	+0.03%	$2.64M	7.02	376K	+103K	+37.8%	12/31/2021
VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.01%	+0.01%	$2.37M	7.02	337K	+256K	+316.7%	12/31/2021
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	+0%	$2.28M	7.02	325K	+27.6K	+9.28%	12/31/2021
HIGHLAND CAPITAL MANAGEMENT FUND ADVISORS, L.P.	0.31%		$2.18M	7.02	310K			12/31/2021
DEUTSCHE BANK AG\	0%	0%	$2.15M	7.02	306K	-264K	-46.3%	12/31/2021
DAFNA Capital Management LLC	0.51%		$2.03M	7.02	289K			12/31/2021
ALTRINSIC GLOBAL ADVISORS LLC	0.06%		$1.9M	7.02	270K			12/31/2021
JACOB ASSET MANAGEMENT OF NEW YORK LLC	0.79%	+0.17%	$1.72M	7.02	245K	+51.5K	+26.7%	12/31/2021
GOLDMAN SACHS GROUP INC	0%	+0%	$1.59M	7.02	227K	+12.3K	+5.71%	12/31/2021
WELLINGTON MANAGEMENT GROUP LLP	0%	+0%	$1.46M	7.02	207K	+207K	NEW	12/31/2021
Bank of New York Mellon Corp	0%		$1.4M	7.03	200K	-337	-0.17%	12/31/2021
DCF Advisers, LLC	0.68%	+0.2%	$1.35M	7.02	192K	+55.6K	+40.7%	12/31/2021
Endurance Wealth Management, Inc.	0.12%	-0.04%	$1.11M	7.02	158K	-46.9K	-22.9%	12/31/2021
Candriam Luxembourg S.C.A.	0.01%	+0.01%	$1.06M	7.02	151K	+151K	NEW	12/31/2021
HRT FINANCIAL LP	0.01%	+0.01%	$1.05M	7.02	149K	+149K	NEW	12/31/2021
AlphaCentric Advisors LLC	0.28%	+0.18%	$962K	7.02	137K	+89.5K	+188.4%	12/31/2021
STIFEL FINANCIAL CORP	0%	+0%	$913K	7.02	130K	+28K	+27.4%	12/31/2021
NEW YORK STATE COMMON RETIREMENT FUND	0%	0%	$795K	7.02	113K	-1.11K	-0.97%	12/31/2021
SG Americas Securities, LLC	0.01%	0%	$789K	7.02	112K	-26.9K	-19.3%	12/31/2021
Allianz Asset Management GmbH	0%	0%	$764K	7.02	109K	-27.4K	-20.1%	12/31/2021
Parametric Portfolio Associates LLC	0%	0%	$704K	7.02	100K	-18.7K	-15.7%	12/31/2021
Swiss National Bank	0%		$688K	7.02	98K			12/31/2021

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* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.