Security Snapshot

ACHIEVE LIFE SCIENCES, INC. - Common Stock, par value $0.001 per share (ACHV) Institutional Ownership

CUSIP: 004468500

13F Institutional Holders and Ownership History from Q3 2020 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

79

Shares (Excl. Options)

21,523,954

Price

$2.94

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Type / Class
Equity / Common Stock, par value $0.001 per share
Symbol
ACHV on Nasdaq
Shares outstanding
102,729,871
Price per share
$4.27
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
21,523,954
Total reported value
$63,555,449
% of total 13F portfolios
0%
Share change
-1,614,690
Value change
-$6,062,639
Number of holders
79
Price from insider filings
$4.27
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • ACHV - ACHIEVE LIFE SCIENCES, INC. - Common Stock, par value $0.001 per share is tracked under CUSIP 004468500.
  • 79 institutions reported positions in Q1 2026.
  • 10 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 77 to 79 between Q4 2025 and Q1 2026.
  • Reported value moved from $115,291,318 to $63,555,449.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 79 institutions filings for Q1 2026.

Open SEC Evidence

Security key

004468500

Latest holder period

Q1 2026

13F holders

79

13D/G owners

10

CIK / CUSIP context first

Significant Owners of ACHIEVE LIFE SCIENCES, INC. - Common Stock, par value $0.001 per share (ACHV) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
TPG GP A, LLC 13% $40,440,170 13,755,160 TPG GP A, LLC 17 Apr 2025
venBio Global Strategic Fund V, L.P. 10% $31,567,712 10,737,317 venBio Global Strategic Fund V, L.P. 15 Apr 2026
Paradigm Biocapital Advisors LP 9.2% $29,116,913 9,903,712 Paradigm BioCapital Advisors LP 17 Apr 2026
Frazier Life Sciences Public Fund, L.P. 6.5% $19,479,817 6,625,788 Frazier Life Sciences Public Fund, L.P. 17 Apr 2026
FRANKLIN RESOURCES INC 6.2% -44% $22,801,922 +$211 6,369,252 +0% Franklin Resources, Inc. 30 Apr 2026
Venrock Healthcare Capital Partners III, L.P. 5.2% $16,176,068 5,502,064 Venrock Healthcare Capital Partners III, L.P. 17 Apr 2026
Alyeska Investment Group, L.P. 5.6% -43% $9,395,574 -$6,098,715 2,982,722 -39% Alyeska Investment Group, L.P. 30 Sep 2025
Contrarian Alpha, LP 4.9% $7,964,388 2,528,377 Parker Quillen 30 Sep 2025
VANGUARD GROUP INC 5% $4,086,493 1,717,014 The Vanguard Group 31 Mar 2025
BlackRock, Inc. 0.6% $711,220 314,699 BlackRock, Inc. 30 Jun 2025

As of 31 Mar 2026, 79 institutional investors reported holding 21,523,954 shares of ACHIEVE LIFE SCIENCES, INC. - Common Stock, par value $0.001 per share (ACHV). This represents 21% of the company’s total 102,729,871 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ACHIEVE LIFE SCIENCES, INC. - Common Stock, par value $0.001 per share (ACHV) together control 20% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FRANKLIN RESOURCES INC 4.3% 4,369,193 0% 0% $12,845,427
Propel Bio Management, LLC 3.7% 3,786,425 0% 7.2% $11,368,992
VANGUARD CAPITAL MANAGEMENT LLC 2.1% 2,204,714 0% 0% $6,481,859
Simplify Asset Management Inc. 1.2% 1,184,512 0% 0.05% $3,482,465
MILLENNIUM MANAGEMENT LLC 1% 1,077,338 -21% 0% $3,167,374
MARSHALL WACE, LLP 0.99% 1,019,281 0% 0% $2,996,686
LPL Financial LLC 0.71% 728,448 +15% 0% $2,141,637
Nantahala Capital Management, LLC 0.63% 648,885 0% 0.12% $1,907,722
RAYMOND JAMES FINANCIAL INC 0.62% 641,925 +7% 0% $1,887,259
GEODE CAPITAL MANAGEMENT, LLC 0.61% 622,785 +3.9% 0% $1,831,935
TWO SIGMA INVESTMENTS, LP 0.57% 588,551 -21% 0% $1,730,340
KVP Capital Advisors, LP 0.45% 462,355 0% 1% $1,359,324
BlackRock, Inc. 0.43% 439,360 +4.8% 0% $1,291,718
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.37% 383,683 -23% 0% $1,128,028
UBS Group AG 0.32% 326,270 +14% 0% $959,234
VANGUARD FIDUCIARY TRUST CO 0.31% 316,177 0% 0% $929,560
STATE STREET CORP 0.25% 254,457 +8.6% 0% $748,104
NORTHERN TRUST CORP 0.22% 224,742 -2.2% 0% $660,741
Shay Capital LLC 0.2% 205,114 -13% 0.09% $603,035
683 Capital Management, LLC 0.19% 200,000 -6.9% 0.05% $588,000
JANE STREET GROUP, LLC 0.17% 176,600 -54% 0% $519,204
GOLDMAN SACHS GROUP INC 0.15% 152,952 -66% 0% $449,679
Lakeside Advisors, INC. 0.11% 111,101 0.22% $326,637
WELLS FARGO & COMPANY/MN 0.1% 101,971 +46% 0% $299,795
Blue Trust, Inc. 0.08% 85,888 0% 0% $252,511

Institutional Holders of ACHIEVE LIFE SCIENCES, INC. - Common Stock, par value $0.001 per share (ACHV) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 21,523,954 $63,555,449 -$6,062,639 $2.94 79
2025 Q4 23,239,545 $115,291,318 +$36,552,641 $4.97 77
2025 Q3 15,541,415 $48,917,159 -$26,338,868 $3.15 65
2025 Q2 26,238,674 $59,299,106 +$26,395,211 $2.26 64
2025 Q1 14,388,656 $38,412,610 -$6,420,566 $2.67 72
2024 Q4 16,340,748 $57,510,675 -$2,280,524 $3.52 70
2024 Q3 16,929,998 $81,217,159 +$2,394,591 $4.74 64
2024 Q2 12,513,128 $58,811,518 +$9,414,756 $4.70 54
2024 Q1 10,495,260 $47,701,835 +$35,368,247 $4.54 39
2023 Q4 2,727,493 $11,236,940 -$1,729,113 $4.12 29
2023 Q3 3,117,219 $13,403,691 -$2,279,792 $4.30 35
2023 Q2 3,562,232 $18,487,663 +$5,645,131 $5.19 38
2023 Q1 2,470,554 $16,600,668 +$3,392,110 $6.80 31
2022 Q4 1,999,698 $4,902,826 -$458,841 $2.45 27
2022 Q3 2,121,733 $7,001,230 +$176,107 $3.30 28
2022 Q2 2,043,015 $9,968,000 -$109,417 $4.88 31
2022 Q1 1,932,821 $14,633,000 -$2,149 $7.57 33
2021 Q4 1,918,795 $14,925,000 +$535,636 $7.78 26
2021 Q3 1,782,658 $15,149,000 -$1,185,059 $8.50 30
2021 Q2 1,948,272 $17,498,000 +$7,592,533 $8.98 28
2021 Q1 1,007,113 $11,662,000 +$6,322,912 $11.58 16
2020 Q4 493,003 $3,994,000 +$307,274 $8.10 14
2020 Q3 452,590 $3,789,000 +$3,789,000 $8.37 12
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