| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| venBio Global Strategic Fund, L.P. | 10% | $14,547,038 | 13,163,549 | GOODMAN COREY S | 02 Feb 2026 | |||
| RA CAPITAL MANAGEMENT, L.P. | 9.9% | $16,265,211 | 13,117,106 | RA Capital Management, L.P. | 02 Feb 2026 | |||
| TCG Crossover GP II, LLC | 9.9% | $14,703,389 | 13,011,849 | Chen Yu | 30 Jan 2026 | |||
| Redmile Group, LLC | 8.5% | $2,042,240 | 4,641,455 | Redmile Group, LLC | 30 Jun 2025 | |||
| HBM Healthcare Investments (Cayman) Ltd. | 8.4% | +27% | $2,295,000 | +$547,266 | 4,500,000 | +31% | HBM Healthcare Investments (Cayman) Ltd. | 31 Mar 2025 |
| TANG CAPITAL PARTNERS LP | 6.3% | $1,681,410 | 3,296,883 | TANG CAPITAL MANAGEMENT, LLC | 31 Dec 2024 | |||
| MILLENNIUM MANAGEMENT LLC | 6% | +18% | $5,706,871 | +$861,071 | 3,188,196 | +18% | Millennium Management LLC | 17 Oct 2025 |
| FMR LLC | 3.4% | $917,426 | 1,798,875 | FMR LLC | 29 Nov 2024 |
As of 30 Sep 2025, 60 institutional investors reported holding 27,785,299 shares of ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO). This represents 21% of the company’s total 132,496,020 outstanding shares.
The largest institutional shareholders of ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO) together control 21% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| venBio Partners LLC | 7.3% | 9,699,925 | 0% | 10% | $17,750,863 |
| Redmile Group, LLC | 2.5% | 3,332,983 | -1.7% | 0.59% | $6,099,359 |
| MILLENNIUM MANAGEMENT LLC | 2% | 2,622,861 | +432% | 0% | $4,799,836 |
| Almitas Capital LLC | 1.9% | 2,536,891 | -0.06% | 1.1% | $4,642,511 |
| VANGUARD GROUP INC | 1.2% | 1,528,619 | -4.5% | 0% | $2,797,372 |
| ACADIAN ASSET MANAGEMENT LLC | 0.92% | 1,220,825 | -3.7% | 0% | $2,233,000 |
| Driehaus Capital Management LLC | 0.6% | 795,777 | 0.01% | $1,456,272 | |
| TWO SIGMA ADVISERS, LP | 0.54% | 719,800 | +2.3% | 0% | $1,317,234 |
| AMERIPRISE FINANCIAL INC | 0.49% | 652,897 | 0% | $1,194,802 | |
| TWO SIGMA INVESTMENTS, LP | 0.46% | 606,671 | +27% | 0% | $1,110,208 |
| BANK OF AMERICA CORP /DE/ | 0.4% | 530,828 | -49% | 0% | $971,415 |
| Privium Fund Management B.V. | 0.38% | 509,059 | 0% | 0.17% | $931,578 |
| BANK OF MONTREAL /CAN/ | 0.36% | 474,781 | -29% | 0% | $868,849 |
| BlackRock, Inc. | 0.34% | 447,692 | -37% | 0% | $819,277 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.27% | 352,335 | +12% | 0% | $645,030 |
| JANE STREET GROUP, LLC | 0.14% | 180,416 | -11% | 0% | $330,161 |
| UBS Group AG | 0.13% | 172,570 | -40% | 0% | $315,803 |
| RENAISSANCE TECHNOLOGIES LLC | 0.12% | 164,499 | +93% | 0% | $301,033 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.09% | 113,063 | -31% | 0% | $206,905 |
| STATE STREET CORP | 0.08% | 111,928 | -9.9% | 0% | $204,828 |
| BANK OF NOVA SCOTIA | 0.08% | 105,858 | 0% | 0% | $193,720 |
| NORTHERN TRUST CORP | 0.07% | 95,160 | -30% | 0% | $174,143 |
| IEQ CAPITAL, LLC | 0.07% | 92,233 | 0% | $168,786 | |
| GSA CAPITAL PARTNERS LLP | 0.07% | 88,165 | +8.4% | 0.01% | $161,000 |
| MORGAN STANLEY | 0.06% | 85,290 | -27% | 0% | $156,081 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 3,084,973 | $3,946,242 | -$26,774 | $1.13 | 12 |
| 2025 Q3 | 27,785,299 | $51,273,440 | +$2,395,861 | $1.83 | 60 |
| 2025 Q2 | 29,030,607 | $12,060,366 | -$2,784,536 | $0.42 | 58 |
| 2025 Q1 | 34,764,459 | $21,657,278 | -$4,297,920 | $0.62 | 83 |
| 2024 Q4 | 41,028,903 | $68,515,761 | -$8,509,648 | $1.67 | 85 |
| 2024 Q3 | 45,458,855 | $83,126,108 | -$40,248,836 | $1.82 | 90 |
| 2024 Q2 | 48,509,608 | $292,389,850 | -$2,826,841 | $6.03 | 107 |
| 2024 Q1 | 45,776,694 | $510,423,087 | -$5,822,832 | $11.15 | 105 |
| 2023 Q4 | 45,764,823 | $681,456,826 | +$185,269,081 | $14.89 | 93 |
| 2023 Q3 | 33,283,050 | $159,762,120 | -$6,348,070 | $4.80 | 75 |
| 2023 Q2 | 34,283,564 | $257,462,824 | -$6,376,897 | $7.51 | 74 |
| 2023 Q1 | 35,697,467 | $161,353,578 | -$6,004,481 | $4.52 | 85 |
| 2022 Q4 | 36,433,730 | $410,607,954 | -$2,049,707 | $11.27 | 85 |
| 2022 Q3 | 36,439,308 | $348,724,761 | +$5,422,376 | $9.57 | 96 |
| 2022 Q2 | 35,930,829 | $290,675,201 | -$16,579,357 | $8.09 | 92 |
| 2022 Q1 | 36,794,716 | $621,886,079 | +$2,845,527 | $16.90 | 94 |
| 2021 Q4 | 36,290,670 | $779,906,251 | -$55,903,331 | $21.49 | 103 |
| 2021 Q3 | 34,508,619 | $2,548,791,083 | +$109,794,972 | $73.86 | 113 |
| 2021 Q2 | 33,314,685 | $1,821,610,718 | -$28,517,807 | $54.68 | 102 |
| 2021 Q1 | 33,493,682 | $2,466,083,905 | +$80,496,245 | $73.74 | 90 |
| 2020 Q4 | 32,294,048 | $2,779,048,270 | +$439,356,967 | $86.20 | 89 |
| 2020 Q3 | 27,250,196 | $1,027,708,220 | +$1,027,708,220 | $37.74 | 56 |