Security Snapshot

ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO) Institutional Ownership

CUSIP: 00166B105

13F Institutional Holders and Ownership History from Q3 2020 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

69

Shares (Excl. Options)

94,268,933

Price

$2.00

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Type / Class
Equity / Common Stock, par value $0.001 per share
Symbol
ALXO on Nasdaq
Shares outstanding
133,751,136
Price per share
$1.68
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
94,268,933
Total reported value
$189,013,299
% of total 13F portfolios
0%
Share change
+62,111,302
Value change
+$125,379,513
Number of holders
69
Price from insider filings
$1.68
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • ALXO - ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share is tracked under CUSIP 00166B105.
  • 69 institutions reported positions in Q1 2026.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 55 to 69 between Q4 2025 and Q1 2026.
  • Reported value moved from $33,447,411 to $189,013,299.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 69 institutions filings for Q1 2026.

Open SEC Evidence

Security key

00166B105

Latest holder period

Q1 2026

13F holders

69

13D/G owners

9

CIK / CUSIP context first

Significant Owners of ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
venBio Global Strategic Fund, L.P. 10% $14,547,038 13,163,549 GOODMAN COREY S 02 Feb 2026
RA CAPITAL MANAGEMENT, L.P. 9.9% $16,265,211 13,117,106 RA Capital Management, L.P. 02 Feb 2026
TCG Crossover GP II, LLC 9.9% $14,703,389 13,011,849 Chen Yu 30 Jan 2026
Redmile Group, LLC 6.8% -19% $18,474,447 +$9,168,330 9,214,188 +99% Redmile Group, LLC 31 Mar 2026
HBM Healthcare Investments (Cayman) Ltd. 6.5% -24% $17,224,337 +$8,201,837 8,590,692 +91% HBM Healthcare Investments (Cayman) Ltd. 31 Mar 2026
TANG CAPITAL PARTNERS LP 6.3% $1,681,410 3,296,883 TANG CAPITAL MANAGEMENT, LLC 31 Dec 2024
LSV Associates, LLC 2.2% $4,943,442 2,942,525 Michael A Carusi 27 May 2026
MILLENNIUM MANAGEMENT LLC 1.5% -75% $3,947,290 -$2,381,279 1,988,559 -38% Millennium Management LLC 31 Mar 2026
FMR LLC 3.4% $917,426 1,798,875 FMR LLC 29 Nov 2024

As of 31 Mar 2026, 69 institutional investors reported holding 94,268,933 shares of ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO). This represents 70% of the company’s total 133,751,136 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO) together control 69% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
RA CAPITAL MANAGEMENT, L.P. 9.7% 13,011,849 0.28% $26,088,757
TCG Crossover Management, LLC 9.7% 13,011,849 0.75% $26,088,757
venBio Partners LLC 9.6% 12,884,638 +33% 9.2% $25,833,699
Redmile Group, LLC 6% 7,964,188 +144% 1.1% $15,968,197
Blackstone Inc. 4.4% 5,826,544 0.05% $11,711,353
Driehaus Capital Management LLC 4.3% 5,734,620 +303% 0.08% $11,497,913
VANGUARD CAPITAL MANAGEMENT LLC 3.1% 4,179,736 0% 0% $8,380,371
MARSHALL WACE, LLP 2.8% 3,757,216 +14145% 0.01% $7,514,432
Vivo Capital, LLC 2.4% 3,184,713 0.53% $6,385,350
Almitas Capital LLC 2.4% 3,173,834 +25% 1.4% $6,363,537
5AM Venture Management, LLC 2.3% 3,057,325 1.7% $6,129,937
ORBIMED ADVISORS LLC 2.1% 2,866,256 0.13% $5,746,843
ADAGE CAPITAL PARTNERS GP, L.L.C. 1.5% 2,000,000 0.01% $4,010,000
MILLENNIUM MANAGEMENT LLC 1.5% 1,988,559 -38% 0% $3,987,061
TWO SIGMA INVESTMENTS, LP 1.2% 1,587,833 +148% 0% $3,183,605
Squadron Capital Management LLC 1.1% 1,460,000 1.2% $2,927,300
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.99% 1,328,907 +780% 0% $2,664,459
ACADIAN ASSET MANAGEMENT LLC 0.82% 1,101,025 -20% 0% $2,202,000
Ensign Peak Advisors, Inc 0.71% 950,550 0% $1,905,853
UBS Group AG 0.68% 914,754 +5.6% 0% $1,834,082
RENAISSANCE TECHNOLOGIES LLC 0.55% 732,599 +73% 0% $1,468,861
BANK OF AMERICA CORP /DE/ 0.43% 577,783 +8.6% 0% $1,158,455
GEODE CAPITAL MANAGEMENT, LLC 0.37% 493,437 +40% 0% $989,757
BlackRock, Inc. 0.33% 447,799 -0.58% 0% $897,836
VANGUARD FIDUCIARY TRUST CO 0.22% 294,478 0% 0% $590,428

Institutional Holders of ALX ONCOLOGY HOLDINGS INC - Common Stock, par value $0.001 per share (ALXO) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 94,268,933 $189,013,299 +$125,379,513 $2.00 69
2025 Q4 29,193,302 $33,447,411 +$624,566 $1.13 55
2025 Q3 27,785,299 $51,273,440 +$2,395,861 $1.83 60
2025 Q2 29,030,607 $12,060,366 -$2,784,536 $0.42 58
2025 Q1 34,764,459 $21,657,278 -$4,297,920 $0.62 83
2024 Q4 41,028,903 $68,515,761 -$8,509,648 $1.67 85
2024 Q3 45,458,855 $83,126,108 -$40,248,836 $1.82 90
2024 Q2 48,509,608 $292,389,850 -$2,826,841 $6.03 107
2024 Q1 45,776,694 $510,423,087 -$5,822,832 $11.15 105
2023 Q4 45,764,823 $681,456,826 +$185,269,081 $14.89 93
2023 Q3 33,283,050 $159,762,120 -$6,348,070 $4.80 75
2023 Q2 34,283,564 $257,462,824 -$6,376,897 $7.51 74
2023 Q1 35,697,467 $161,353,578 -$6,004,481 $4.52 85
2022 Q4 36,433,730 $410,607,954 -$2,049,707 $11.27 85
2022 Q3 36,439,308 $348,724,761 +$5,422,376 $9.57 96
2022 Q2 35,930,829 $290,675,201 -$16,579,357 $8.09 92
2022 Q1 36,794,716 $621,886,079 +$2,845,527 $16.90 94
2021 Q4 36,290,670 $779,906,251 -$55,903,331 $21.49 103
2021 Q3 34,508,619 $2,548,791,083 +$109,794,972 $73.86 113
2021 Q2 33,314,685 $1,821,610,718 -$28,517,807 $54.68 102
2021 Q1 33,493,682 $2,466,083,905 +$80,496,245 $73.74 90
2020 Q4 32,294,048 $2,779,048,270 +$439,356,967 $86.20 89
2020 Q3 27,250,196 $1,027,708,220 +$1,027,708,220 $37.74 56
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