ALPS ETF TR - MED BREAKTHGH (SBIO) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2014 to Q4 2025

Type / Class: Equity / MED BREAKTHGH
Symbol: SBIO
Price per share: $51.22
All holders as of 30 Sep 2025: Q3 2025
Total 13F shares: 2,465,502
Total reported value: $74,444,181
% of total 13F portfolios: 0%
Share change: -299,354
Value change: -$11,326,387
Number of holders: 38

Reported Shares, Excluding Options vs Price

Reported Value, Excluding Options

Total Investors

As of 30 Sep 2025, 38 institutional investors reported holding 2,465,502 shares of ALPS ETF TR - MED BREAKTHGH (SBIO).

Institutional Holders of ALPS ETF TR - MED BREAKTHGH (SBIO) across Reporting Periods

Period	Reported Shares, Excl. Options	Value, Excl. Options	Value Change	Puts Notional Value	Calls Notional Value	Price (Median)	Investors
2025 Q4	51,011	$2,607,048	-$23,257,825			$51.22	5
2025 Q3	2,465,502	$74,444,181	-$11,326,387			$38.86	38
2025 Q2	2,764,856	$74,301,622	-$3,456,421	$0	$0	$30.07	35
2025 Q1	2,884,515	$72,984,477	+$30,442,868	$5,704	$34,222	$28.52	33
2024 Q4	1,485,462	$49,097,003	+$1,990,552	$6,606	$33,030	$33.03	35
2024 Q3	1,434,930	$52,950,164	-$250,446		$0	$37.33	36
2024 Q2	1,418,814	$47,816,949	-$668,734	$0	$13,433	$33.58	37
2024 Q1	1,438,262	$51,309,167	+$5,137,206	$71,500	$475,475	$35.75	37
2023 Q4	1,295,478	$42,712,132	-$1,463,633	$131,765	$250,345	$32.94	34
2023 Q3	1,344,986	$36,611,445	-$2,061,644	$108,884	$321,197	$27.22	35
2023 Q2	1,406,121	$44,270,591	-$128,381	$37,860	$873,935	$31.55	40
2023 Q1	1,408,132	$38,280,082	-$1,363,931	$54,369	$201,166	$27.18	37
2022 Q4	1,459,524	$44,254,889	+$14,757,407	$72,912	$258,230	$30.38	45
2022 Q3	963,215	$29,018,762	-$2,264,410		$280,000	$30.11	40
2022 Q2	1,054,443	$29,216,470	-$6,634,393		$498,000	$27.69	48
2022 Q1	1,289,137	$43,377,551	-$11,112,049		$1,197,000	$33.64	54
2021 Q4	1,618,337	$67,537,782	+$2,754,720	$0	$1,538,000	$42.24	62
2021 Q3	1,463,462	$66,604,390	-$332,962	$218,000	$1,388,000	$45.51	59
2021 Q2	1,467,528	$71,788,731	-$1,972,757	$519,000	$1,571,000	$48.91	63
2021 Q1	1,505,223	$75,661,850	+$3,024,487	$573,000	$2,609,000	$50.27	67
2020 Q4	1,444,766	$74,056,022	-$1,670,344	$323,000	$1,967,000	$51.22	65
2020 Q3	1,478,637	$60,818,238	-$1,490,077	$0	$1,361,000	$41.13	51
2020 Q2	1,500,395	$62,744,601	+$2,563,590	$213,000	$1,791,000	$41.83	51
2020 Q1	1,465,422	$46,457,127	+$4,232,484	$241,000	$831,000	$31.70	44
2019 Q4	1,306,707	$55,225,451	-$2,996,716		$3,767,000	$42.28	51
2019 Q3	1,379,578	$44,001,929	+$751,133	$0	$2,338,000	$31.56	45
2019 Q2	1,346,627	$48,640,787	+$2,080,334	$213,000	$2,395,000	$36.12	45
2019 Q1	1,297,189	$46,924,684	-$8,654,500	$785,000	$1,914,000	$36.18	45
2018 Q4	1,596,572	$44,998,968	-$17,931,866	$0	$839,000	$28.14	47
2018 Q3	2,142,561	$84,351,772	+$15,619,448	$882,000	$901,000	$39.37	54
2018 Q2	1,755,840	$65,417,636	+$16,203,717	$373,000	$917,000	$37.27	45
2018 Q1	1,317,259	$45,080,673	+$20,163,506	$644,000	$1,356,000	$34.22	42
2017 Q4	727,746	$23,871,263	+$3,261,647	$603,000	$597,000	$32.78	34
2017 Q3	617,099	$19,236,387	+$714,608	$530,000	$703,000	$31.17	28
2017 Q2	596,596	$16,615,003	-$3,744,751	$554,000	$379,000	$27.85	25
2017 Q1	739,994	$19,042,496	+$1,173,999	$286,000	$592,000	$25.76	27
2016 Q4	701,962	$16,118,143	-$1,261,233	$0	$316,000	$22.92	26
2016 Q3	750,229	$19,572,000	+$4,481,033	$475,000	$463,000	$26.10	28
2016 Q2	579,496	$13,155,068	-$998,792	$668,000	$849,000	$22.63	27
2016 Q1	618,604	$13,648,875	-$9,403,109	$0		$21.91	22
2015 Q4	997,368	$31,080,512	+$12,923,911	$747,000		$31.73	31
2015 Q3	575,209	$16,104,325	+$5,730,602	$589,000		$27.88	29
2015 Q2	361,555	$12,842,975	+$8,982,779			$35.52	18
2015 Q1	109,334	$3,273,487	+$1,860,487			$29.91	13
2014 Q4	56,793	$1,411,000	+$1,411,000			$24.92	2