Insider Trading & Ownership of Darwin Global Management, Ltd.

Location: St. Helier, Jersey
Summary: The estimated value of insider holdings of Darwin Global Management, Ltd. is at least $306M dollars as of 28 Jun 2023. Darwin Global Management, Ltd. is the 10%+ Owner of Ambrx Biopharma Inc. and owns shares of Ambrx Biopharma Cayman, Inc. stock worth about $306M.
Signature: Darwin Global Management, Ltd. By: /s/ John Legge, Director and Chief Financial Officer
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Ownership of Darwin Global Management, Ltd.

Symbol	Company	Relationship	Holdings Value	Past Year Net Change	Change %	Report Period
AMAM	Ambrx Biopharma Cayman, Inc.	10%+ Owner	$306M			27 Jun 2023

Sym	Company	Class	Transaction	%	Value $	* Price $	Shares	Shares After	Date	Ownership

* An asterisk sign (*) next to the price indicates that the price is likely invalid.