| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| ABG Management Ltd. | 12% | 6,058,738 | 0 | 6,058,738 | By: /s/ Fan Yu | Fan Yu, Director | |
| Ally Bridge Group (NY) LLC | 12% | 6,058,738 | 0 | 6,058,738 | By: ABG Management Ltd., its managing member, By: /s/ Fan Yu | Fan Yu, Director | |
| Ally Bridge MedAlpha Master Fund L.P. | 12% | 6,058,738 | 0 | 6,058,738 | By: Ally Bridge Group (NY) LLC, its manager, By: ABG Management Ltd., its managing member, By: /s/ Fan Yu | Fan Yu, Director | |
| Fan Yu | 12% | 6,058,738 | 0 | 6,058,738 | /s/ Fan Yu | Fan Yu |