| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Public Fund, L.P. | 8.7% | 1.95M | 0 | 1.95M | /s/ Steve R. Bailey | By Steve R. Bailey, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P., GP of Frazier Life Sciences Public Fund, L.P. | |
| FHMLSP, L.P. | 8.7% | 1.95M | 0 | 1.95M | /s/ Steve R. Bailey | By Steve R. Bailey, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P. | |
| FHMLSP, L.L.C. | 8.7% | 1.95M | 0 | 1.95M | /s/ Steve R. Bailey | By Steve R. Bailey, CFO of FHMLSP, L.L.C. |