| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Stonepine Capital Management, LLC | 5% | 2,833,333 | 0 | 2,833,333 | /s/ Jon M. Plexico | Managing Member | |
| Stonepine Capital, L.P. | 5% | 2,833,333 | 0 | 2,833,333 | /s/ Jon M. Plexico | Managing Member of the General Partner, Stonepine GP, LLC | |
| Stonepine GP, LLC | 5% | 2,833,333 | 0 | 2,833,333 | /s/ Jon M. Plexico | Managing Member | |
| Jon M. Plexico | 5% | 2,833,333 | 0 | 2,833,333 | /s/ Jon M. Plexico | Reporting person |