James B. Tananbaum - 01 Apr 2026 Form 4 Insider Report for ALUMIS INC. (ALMS)

Reporting relationship: Director, 10%+ Owner
Issuer ticker: ALMS
Reported as of: 01 Apr 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 03 Apr 2026, 15:53:34 UTC
Prior SEC filing: 12 Jan 2026
Source filing: View source filing
Reporting owner signature: /s/ James B. Tananbaum

Key filing fact

James B. Tananbaum filed Form 4 for ALUMIS INC. (ALMS) on 03 Apr 2026.

Key facts

This page summarizes James B. Tananbaum's Form 4 filing for ALUMIS INC. (ALMS).
4 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 03 Apr 2026, 15:53.

Change

Previous filing in this sequence was filed on 12 Jan 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001581754 Primary reporting owner

Tananbaum James B.

Relationship: Director, 10%+ Owner
Address: 900 LARKSPUR LANDING CIRCLE, SUITE 150, LARKSPUR
Signature: /s/ James B. Tananbaum
Signature date: 03 Apr 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ALMS transaction

Common Stock

Other

Transaction value
Shares: -1,176,470
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F1, F2

ALMS transaction

Common Stock

Other

Transaction value
Shares: +1,123,337
Change %
Price: $0.000000^*
Shares after: 1,123,337
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F3, F4

ALMS transaction

Common Stock

Other

Transaction value
Shares: -1,123,337
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F4, F5

ALMS transaction

Common Stock

Other

Transaction value
Shares: +680,486
Change %
Price: $0.000000^*
Shares after: 680,486
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F6, F7

ALMS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 5,702,536
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F8

ALMS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 2,908,332
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F9

ALMS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 4,247,670
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F10

ALMS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 194,459
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F11

ALMS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 1,960,337
Date: 01 Apr 2026
Ownership: See Footnote
Footnotes: F12

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 12 footnotes

Footnote F1

Represents a pro rata, in-kind distribution, and not a purchase or sale, without additional consideration by Foresite Labs Affiliates 2021, LLC ("Labs Affiliates") to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Securities Exchange Act of 1934, as amended (the "Exchange Act").

Footnote F2

The shares are held of record by Labs Affiliates. Foresite Labs, LLC ("Labs") is the managing member of Labs Affiliates and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), a manager of Labs, may be deemed to share voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs Affiliates, except to the extent of his pecuniary interest in such securities.

Footnote F3

Represents shares received by Labs pursuant to pro rata distributions by Labs Affiliates, for no consideration, to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Exchange Act.

Footnote F4

The shares are held of record by Labs. Tananbaum, a manager of Labs, may be deemed to share voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs, except to the extent of his pecuniary interest in such securities.

Footnote F5

Represents a pro rata, in-kind distribution, and not a purchase or sale, without additional consideration by Labs to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Exchange Act.

Footnote F6

Represents shares received by TFL Investment Holdings, LLC ("TFL") pursuant to pro rata distributions by Labs, for no consideration, to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Exchange Act.

Footnote F7

The shares are held of record by TFL. Tananbaum is the manager of TFL, and James B. Tananbaum and Dana Shonfeld Tananbaum Family Trust, of which Tananbaum is a trustee, is the sole member of TFL.

Footnote F8

The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Fund V, except to the extent of his pecuniary interest in such securities.

Footnote F9

The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of his pecuniary interest in such securities.

Footnote F10

The shares are held of record by Foresite Capital Fund VI, L.P. ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCM VI, may be deemed to have sole voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Fund VI, except to the extent of his pecuniary interest in such securities.

Footnote F11

The shares are held of record by Labs Co-Invest V, LLC ("Labs Co-Invest"). FCM V is the managing member of Labs Co-Invest and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs Co-Invest, except to the extent of his pecuniary interest in such securities.

Footnote F12

The shares are held of record by Foresite Labs Fund I, L.P. ("Labs Fund I"). Foresite Labs Management I, LLC ("FLM I") is the general partner of Labs Fund I and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FLM I, may be deemed to have sole voting and dispositive power over such shares. Tananbaum disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs Fund I, except to the extent of his pecuniary interest in such securities.

SEC remarks

This Form 4 is one of three Form 4s filed on the date hereof in respect of these transactions. The Reporting Persons for the other Form 4s are Fund V, Opportunity Fund V, Labs Co-Invest, Fund VI, Labs Fund I, Labs Affiliates, FCM V, FCOM V, FCM VI, FLM I and Labs.

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