Krish S. Krishnan - 27 Feb 2026 Form 4 Insider Report for Krystal Biotech, Inc. (KRYS)

Source evidence Original filing metadata and source links for verification. 5 source fields
SEC form
4
Accepted by SEC
03 Mar 2026, 18:30:23 UTC
Prior SEC filing
05 Dec 2025
Next SEC filing
06 Mar 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ Krish S. Krishnan

Key filing fact

Krish S. Krishnan filed Form 4 for Krystal Biotech, Inc. (KRYS) on 03 Mar 2026.

Key facts

  • This page summarizes Krish S. Krishnan's Form 4 filing for Krystal Biotech, Inc. (KRYS).
  • 15 reported transactions and 5 derivative rows are listed below.
  • Accepted by SEC: 03 Mar 2026, 18:30.

Change

  • Previous filing in this sequence was filed on 05 Dec 2025.
  • Current net transaction value: -$8,430,174.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001298709 Primary reporting owner

Krishnan Krish S

Relationship
President and CEO, Director, 10%+ Owner
Address
C/O KRYSTAL BIOTECH, INC., 2100 WHARTON STREET, SUITE 701, PITTSBURGH
Signature
/s/ Krish S. Krishnan
Signature date
03 Mar 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

KRYS transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+8,750
Change %
+0.59%
Price
$0.000000
Shares after
1,486,806
Date
27 Feb 2026
Ownership
Direct
Footnotes
F1
KRYS transaction

Common Stock

Tax liability

Transaction value
$1,097,323
Shares
-3,981
Change %
-0.27%
Price
$275.64
Shares after
1,482,825
Date
27 Feb 2026
Ownership
Direct
Footnotes
F2, F3
KRYS transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+26,250
Change %
+1.8%
Price
$0.000000
Shares after
1,509,075
Date
27 Feb 2026
Ownership
Direct
Footnotes
F4
KRYS transaction

Common Stock

Tax liability

Transaction value
$3,291,693
Shares
-11,942
Change %
-0.79%
Price
$275.64
Shares after
1,497,133
Date
27 Feb 2026
Ownership
Direct
Footnotes
F3, F5
KRYS transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+5,725
Change %
+0.38%
Price
$0.000000
Shares after
1,502,858
Date
27 Feb 2026
Ownership
Direct
Footnotes
F6
KRYS transaction

Common Stock

Tax liability

Transaction value
$718,042
Shares
-2,605
Change %
-0.17%
Price
$275.64
Shares after
1,500,253
Date
27 Feb 2026
Ownership
Direct
Footnotes
F3, F7
KRYS transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+22,500
Change %
+1.6%
Price
$0.000000
Shares after
1,436,211
Date
27 Feb 2026
Ownership
By Spouse
Footnotes
F8, F9, F10
KRYS transaction

Common Stock

Tax liability

Transaction value
$2,821,451
Shares
-10,236
Change %
-0.71%
Price
$275.64
Shares after
1,425,975
Date
27 Feb 2026
Ownership
By Spouse
Footnotes
F3, F9, F10, F11
KRYS transaction

Common Stock

Options Exercise

Transaction value
$0
Shares
+4,000
Change %
+0.28%
Price
$0.000000
Shares after
1,429,975
Date
27 Feb 2026
Ownership
By Spouse
Footnotes
F9, F10, F12
KRYS transaction

Common Stock

Tax liability

Transaction value
$501,665
Shares
-1,820
Change %
-0.13%
Price
$275.64
Shares after
1,428,155
Date
27 Feb 2026
Ownership
By Spouse
Footnotes
F3, F9, F10, F13
KRYS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
90,000
Date
27 Feb 2026
Ownership
By Krishnan Spousal Trust
KRYS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
50,000
Date
27 Feb 2026
Ownership
By Krishnan Family Trust
Footnotes
F14

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

KRYS transaction Derivative

Restricted Stock Units

Options Exercise

Transaction value
$0
Shares
-8,750
Change %
-33%
Price
$0.000000
Shares after
17,500
Date
27 Feb 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
8,750
Exercise price
Footnotes
F1
KRYS transaction Derivative

Performance Stock Units

Options Exercise

Transaction value
$0
Shares
-26,250
Change %
-100%
Price
$0.000000
Shares after
0
Date
27 Feb 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
26,250
Exercise price
Footnotes
F4
KRYS transaction Derivative

Restricted Stock Units

Options Exercise

Transaction value
$0
Shares
-5,725
Change %
-25%
Price
$0.000000
Shares after
17,175
Date
27 Feb 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
5,725
Exercise price
Footnotes
F6
KRYS transaction Derivative

Stock Option (Right to Buy)

Award

Transaction value
$0
Shares
+45,249
Change %
Price
$0.000000
Shares after
45,249
Date
27 Feb 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
45,249
Exercise price
$275.64
Footnotes
F15
KRYS transaction Derivative

Restricted Stock Units

Award

Transaction value
$0
Shares
+18,140
Change %
Price
$0.000000
Shares after
18,140
Date
27 Feb 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
18,140
Exercise price
Footnotes
F16, F17, F18
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 18 footnotes

Footnote F1

35,000 restricted stock units ("RSUs") were granted on February 29, 2024. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period. 8,750 RSUs vested on February 27, 2026.

Footnote F2

Represents the number of shares of common stock surrendered to the Company for tax withholding upon the vesting of 8,750 RSUs on February 27, 2026.

Footnote F3

The closing price on February 27, 2026 of the Company's common stock on the Nasdaq Global Select Market.

Footnote F4

52,500 performance stock units ("PSUs") were granted on February 29, 2024. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 26,250 PSUs, vested on February 27, 2026.

Footnote F5

Represents the number of shares of common stock surrendered to the Company for tax withholding upon the vesting of 26,250 PSUs on February 27, 2026.

Footnote F6

22,900 restricted stock units ("RSUs") were granted on February 28, 2025. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 5,725 RSUs, vesting on February 27, 2026.

Footnote F7

Represents the number of shares of common stock surrendered to the Company for tax withholding upon the vesting of 5,725 RSUs on February 27, 2026.

Footnote F8

45,000 performance stock units ("PSUs") were granted on February 29, 2024, to the Reporting Person's spouse, Suma M. Krishnan. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's spouse continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 22,500 PSUs, vested on February 27, 2026.

Footnote F9

These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Suma M. Krishnan.

Footnote F10

Directly beneficially owned by Suma M. Krishnan, the spouse of the Reporting Person.

Footnote F11

Represents number of shares of common stock surrendered to the Company for tax withholding by the Reporting Person's spouse, Suma M. Krishnan, upon the vesting of 22,500 PSUs on February 27, 2026.

Footnote F12

16,000 restricted stock units ("RSUs") were granted on February 28, 2025 to the Reporting Person's spouse, Suma M. Krishnan. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's spouse continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 4,000 RSUs, vesting on February 27, 2026.

Footnote F13

Represents number of shares of common stock surrendered to the Company for tax withholding by the Reporting Person's spouse, Suma M. Krishnan, upon the vesting of 4,000 RSUs on February 27, 2026.

Footnote F14

Directly beneficially owned by the Krishnan Family Trust. The Reporting Person and his spouse are each joint beneficial owners of the trust with joint voting and investment control.

Footnote F15

The stock options vests in four equal annual installments beginning on February 27, 2027.

Footnote F16

Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date.

Footnote F17

The number of RSUs in this column represents the number of shares of common stock the Reporting Person will receive assuming the Reporting Person's continued service to the Company on all applicable vesting dates.

Footnote F18

The RSUs vest in four equal annual installments with the first installment vesting on February 27, 2027.

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