Gregory A. Demopulos MD - 18 Feb 2026 Form 4 Insider Report for OMEROS CORP (OMER)

Reporting relationship: Chairman, CEO & President, Director
Issuer ticker: OMER
Reported as of: 18 Feb 2026
Net transaction value: -$159,099
SEC form: 4
Accepted by SEC: 20 Feb 2026, 21:40:28 UTC
Prior SEC filing: 15 Oct 2025
Next SEC filing: 24 Jul 2026
Source filing: View source filing
Reporting owner signature: /s/ Peter B. Cancelmo, Attorney-in-Fact

Key filing fact

Gregory A. Demopulos MD filed Form 4 for OMEROS CORP (OMER) on 20 Feb 2026.

Key facts

This page summarizes Gregory A. Demopulos MD's Form 4 filing for OMEROS CORP (OMER).
3 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 20 Feb 2026, 21:40.

Change

Previous filing in this sequence was filed on 15 Oct 2025.
Current net transaction value: -$159,099.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001472160 Primary reporting owner

Demopulos Gregory A MD

Relationship: Chairman, CEO & President, Director
Address: 201 ELLIOTT AVENUE WEST, SEATTLE
Signature: /s/ Peter B. Cancelmo, Attorney-in-Fact
Signature date: 20 Feb 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

OMER transaction

Common stock

Options Exercise

Transaction value: $4,108,000
Shares: +400,000
Change %: +28%
Price: $10.27
Shares after: 1,826,986
Date: 18 Feb 2026
Ownership: Direct

OMER transaction

Common stock

Tax liability

Transaction value: $4,267,099
Shares: -357,678
Change %: -20%
Price: $11.93
Shares after: 1,469,308
Date: 18 Feb 2026
Ownership: Direct
Footnotes: F1

OMER holding

Common stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 300,000
Date: 18 Feb 2026
Ownership: By trust
Footnotes: F2, F3

OMER holding

Common stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 300,000
Date: 18 Feb 2026
Ownership: By trust
Footnotes: F2, F4

OMER holding

Common stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 123,945
Date: 18 Feb 2026
Ownership: By spouse
Footnotes: F2

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

OMER transaction Derivative

Stock option (right to buy)

Options Exercise

Transaction value: $0
Shares: -400,000
Change %: -100%
Price: $0.000000
Shares after: 0
Date: 18 Feb 2026
Ownership: Direct
Underlying class: Common stock
Underlying amount: 400,000
Exercise price: $10.27
Footnotes: F5

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 5 footnotes

Footnote F1

Represents shares withheld by Omeros Corporation ("Omeros") in connection with net share settlement to satisfy the exercise price and tax liability associated with the reporting person's exercise of stock options. The number of shares withheld was determined based on the closing price of Omeros' common stock on February 17, 2026. The transaction did not involve any open-market sale of securities, and all 357,678 withheld shares remained in the Omeros treasury.

Footnote F2

The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, if any, and nothing in this report shall be deemed an admission that the reporting person is the beneficial owner of such securities under Section 16 of the Securities Exchange Act of 1934 or for any other purpose.

Footnote F3

Shares held in the [Demopulos Child #1] Gift Trust, an irrevocable trust established for the benefit of a minor child of the reporting person.

Footnote F4

Shares held in the [Demopulos Child #2] Gift Trust, an irrevocable trust established for the benefit of a minor child of the reporting person.

Footnote F5

This option vested and became exercisable over 48 equal monthly installments, with a vesting commencement date of April 1, 2015.