ABG Management Ltd. - 03 Feb 2026 Form 4 Insider Report for ProMIS Neurosciences Inc. (PMN)

Reporting relationship: 10%+ Owner
Issuer ticker: PMN
Reported as of: 03 Feb 2026
Net transaction value: +$8,499,988
SEC form: 4
Accepted by SEC: 05 Feb 2026, 19:00:01 UTC
Prior SEC filing: 24 Oct 2025
Source filing: View source filing
Reporting owner signature: ABG Management Ltd., By: /s/ Fan Yu, Director

Key filing fact

ABG Management Ltd. filed Form 4 for ProMIS Neurosciences Inc. (PMN) on 05 Feb 2026.

Key facts

This page summarizes ABG Management Ltd.'s Form 4 filing for ProMIS Neurosciences Inc. (PMN).
2 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 05 Feb 2026, 19:00.

Change

Previous filing in this sequence was filed on 24 Oct 2025.
Current net transaction value: +$8,499,988.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (5)

CIK 0001832106 Primary reporting owner

ABG Management Ltd.

Relationship: 10%+ Owner
Address: #3902, 39/F, E TOWER, 10 HARCOURT RD CTR, HONG KONG, HONG KONG
Signature: ABG Management Ltd., By: /s/ Fan Yu, Director
Signature date: 05 Feb 2026

CIK 0001831963

Ally Bridge MedAlpha Master Fund L.P.

Relationship: 10%+ Owner
Address: C/O MAPLES CORPORATE SERVICES LIMITED,, P.O. BOX 309, UGLAND HOUSE,, GRAND CAYMAN,, CAYMAN ISLANDS
Signature: Ally Bridge MedAlpha Master Fund L.P., By: Ally Bridge Group (NY) LLC, its manager, By: ABG Management Ltd., its managing member, By: /s/ Fan Yu, Director
Signature date: 05 Feb 2026

CIK 0001822947

Ally Bridge Group (NY) LLC

Relationship: 10%+ Owner
Address: 430 PARK AVENUE, 12TH FLOOR, NEW YORK,
Signature: Ally Bridge Group (NY) LLC, By: ABG Management Ltd., its managing member, By: /s/ Fan Yu, Director
Signature date: 05 Feb 2026

CIK 0001668029

Yu Fan

Relationship: 10%+ Owner
Address: #3902, 39/F, E TOWER,, 10 HARCOURT RD CTR, HONG KONG, HONG KONG
Signature: /s/ Fan Yu
Signature date: 05 Feb 2026

CIK 0002092283

Alex Slanix Paul

Relationship: Director
Address: C/O PROMIS NEUROSCIENCES INC., SUITE 200, 1920 YONGE STREET, TORONTO,, ONTARIO, CANADA
Signature: /s/ Michael Bendetson, Attorney-in-Fact for Slanix Alex
Signature date: 05 Feb 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

PMN transaction

Common Shares

Purchase

Transaction value: $8,499,988
Shares: +700,741
Change %: +289%
Price: $12.13
Shares after: 943,090
Date: 03 Feb 2026
Ownership: See Footnote
Footnotes: F1, F2, F3, F4, F5

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

PMN transaction Derivative

Warrants

Purchase

Transaction value
Shares: +700,741
Change %
Price
Shares after: 700,741
Date: 03 Feb 2026
Ownership: See Footnote
Underlying class: Common Shares
Underlying amount: 700,741
Exercise price: $14.40
Footnotes: F1, F3, F4, F5, F6, F7

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 7 footnotes

Footnote F1

The Warrants were purchased together with the Common Shares reported herein for an aggregate purchase price of $12.13 per Common Share.

Footnote F2

The Common Shares reported herein include: (i) 407,230 Common Shares held of record by Ally Bridge MedAlpha Master Fund L.P., (ii) 329,760 Common Shares held of record by ABG V-SIV IX Limited and (iii) 206,100 Common Shares held of record by ABG V-SIV X Limited.

Footnote F3

Mr. Fan Yu is the controlling stockholder of ABG Management Ltd., which is the sole member of Ally Bridge Group (NY) LLC, which manages the investments of Ally Bridge MedAlpha Master Fund L.P. As such, each of the foregoing entities and Mr. Fan Yu may be deemed to share beneficial ownership of the securities held of record by Ally Bridge MedAlpha Master Fund L.P.

Footnote F4

Mr. Fan Yu is also the indirect controlling stockholder of ABG Global Life Science Capital Partners V GP Limited, which is the general partner of ABG Global Life Science Capital Partners V GP, L.P., which is the general partner of Ally Bridge Group Global Life Science Capital Partners V, L.P., which is the controlling shareholder of ABG V-SIV IX Limited. As such, each of the foregoing entities and Mr. Fan Yu may be deemed to share beneficial ownership of the securities held of record by ABG V-SIV IX Limited.

Footnote F5

Mr. Fan Yu is also the controlling stockholder of ABG V-SIV X Limited. As such, Mr. Fan Yu may be deemed to share beneficial ownership of the securities held of record by ABG V-SIV X Limited.

Footnote F6

The warrants to purchase Common Shares (the "Warrants") are exercisable immediately and will expire upon the earlier of (i) within 60 days of the Milestone Event or (ii) February 3, 2031. For purposes of the foregoing, the "Milestone Event" means the public announcement via press release or the filing of a Current Report on Form 8-K by the Issuer of topline data from the cohorts treated with single ascending doses of PMN310.

Footnote F7

The Warrants reported herein include: (i) Warrants to purchase 164,881 Common Shares held of record by Ally Bridge MedAlpha Master Fund L.P., (ii) Warrants to purchase 329,760 Common Shares held of record by ABG V-SIV IX Limited and (iii) Warrants to purchase 206,100 Common Shares held of record by ABG V-SIV X Limited.

SEC remarks

Each of ABG Global Life Science Capital Partners V GP Limited, ABG Global Life Science Capital Partners V GP, L.P., Ally Bridge Group Global Life Science Capital Partners V, L.P., ABG V-SIV IX Limited and ABG V-SIV X Limited will file a Form 3 in connection with the transactions reported herein and thereafter are expected to file Forms 4 jointly with the reporting persons.