George D. Yancopoulos - 09 Dec 2025 Form 4 Insider Report for REGENERON PHARMACEUTICALS, INC. (REGN)

Reporting relationship: Bd. Co-Chair, President & CSO, Director
Issuer ticker: REGN
Reported as of: 09 Dec 2025
Net transaction value: -$10,930,239
SEC form: 4
Accepted by SEC: 11 Dec 2025, 16:27:23 UTC
Prior SEC filing: 12 Jun 2024
Next SEC filing: 05 Jan 2026
Source filing: View source filing
Reporting owner signature: /s/ George D. Yancopoulos

Key filing fact

George D. Yancopoulos filed Form 4 for REGENERON PHARMACEUTICALS, INC. (REGN) on 11 Dec 2025.

Key facts

This page summarizes George D. Yancopoulos's Form 4 filing for REGENERON PHARMACEUTICALS, INC. (REGN).
3 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 11 Dec 2025, 16:27.

Change

Previous filing in this sequence was filed on 12 Jun 2024.
Current net transaction value: -$10,930,239.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001226690 Primary reporting owner

YANCOPOULOS GEORGE

Relationship: Bd. Co-Chair, President & CSO, Director
Address: 777 OLD SAW MILL RIVER ROAD, TARRYTOWN
Signature: /s/ George D. Yancopoulos
Signature date: 11 Dec 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

REGN transaction

Common Stock

Options Exercise

Transaction value: $81,580,691
Shares: +146,815
Change %: +50%
Price: $555.67
Shares after: 442,334
Date: 09 Dec 2025
Ownership: Direct

REGN transaction

Common Stock

Tax liability

Transaction value: $92,510,930
Shares: -131,874
Change %: -30%
Price: $701.51
Shares after: 310,460
Date: 09 Dec 2025
Ownership: Direct

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 71,487
Date: 09 Dec 2025
Ownership: By 2024 GRAT

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 200,000
Date: 09 Dec 2025
Ownership: By 2025 GRAT

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 200,000
Date: 09 Dec 2025
Ownership: By 2025 GRAT II

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 5,962
Date: 09 Dec 2025
Ownership: By 401(k) Plan

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 180,000
Date: 09 Dec 2025
Ownership: By Trust for Chldn.
Footnotes: F1

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 101,988
Date: 09 Dec 2025
Ownership: by 2024 GRAT II

REGN holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 56,048
Date: 09 Dec 2025
Ownership: by Children

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

REGN transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value: $0
Shares: -146,815
Change %: -100%
Price: $0.000000
Shares after: 0
Date: 09 Dec 2025
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 146,815
Exercise price: $555.67
Footnotes: F2

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 2 footnotes

Footnote F1

As investment trustee of trusts for the benefit of the reporting person's children.

Footnote F2

The stock option award vested in four equal annual installments, commencing one year after the date of grant.

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