Third Rock Ventures IV, L.P. - 04 Nov 2025 Form 4 Insider Report for Maze Therapeutics, Inc. (MAZE)

Reporting relationship: 10%+ Owner
Issuer ticker: MAZE
Reported as of: 04 Nov 2025
Net transaction value: $0
SEC form: 4
Accepted by SEC: 05 Nov 2025, 16:15:08 UTC
Prior SEC filing: 27 Oct 2025
Source filing: View source filing
Reporting owner signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC, general partner of Third Rock Ventures GP IV, L.P., general partner of Third Rock Ventures IV, L.P.

Key filing fact

Third Rock Ventures IV, L.P. filed Form 4 for Maze Therapeutics, Inc. (MAZE) on 05 Nov 2025.

Key facts

This page summarizes Third Rock Ventures IV, L.P.'s Form 4 filing for Maze Therapeutics, Inc. (MAZE).
1 reported transaction and 0 derivative rows are listed below.
Accepted by SEC: 05 Nov 2025, 16:15.

Change

Previous filing in this sequence was filed on 27 Oct 2025.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (6)

CIK 0001688327 Primary reporting owner

Third Rock Ventures IV, L.P.

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC, general partner of Third Rock Ventures GP IV, L.P., general partner of Third Rock Ventures IV, L.P.
Signature date: 05 Nov 2025

CIK 0001688326

Third Rock Ventures GP IV, L.P.

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC, general partner of Third Rock Ventures GP IV, L.P.
Signature date: 05 Nov 2025

CIK 0001688325

TRV GP IV, LLC

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC
Signature date: 05 Nov 2025

CIK 0001778071

Third Rock Ventures V, L.P.

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP V, LLC, general partner of Third Rock Ventures GP V, L.P., general partner of Third Rock Ventures V, L.P.
Signature date: 05 Nov 2025

CIK 0001977498

Third Rock Ventures GP V, LP

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP V, LLC, general partner of Third Rock Ventures GP V, L.P.
Signature date: 05 Nov 2025

CIK 0001990717

TRV GP V, LLC

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP V, LLC
Signature date: 05 Nov 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

MAZE transaction

Common Stock

Other

Transaction value
Shares: -1,600,000
Change %: -26%
Price
Shares after: 4,473,958
Date: 04 Nov 2025
Ownership: Direct
Footnotes: F1, F2, F4

MAZE holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 950,800
Date: 04 Nov 2025
Ownership: See Footnotes
Footnotes: F3, F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 4 footnotes

Footnote F1

On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended.

Footnote F2

The shares are held directly by TRV IV. The general partner of TRV IV is TRV GP IV. The general partner of TRV GP IV is TRV GP IV LLC. Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

Footnote F3

The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

Footnote F4

Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.